Low dose naltrexone

[Guest guest]

I took one pill...1.4 mg 2 nights in a row, but I am having trouble

slleping....You suggested i get in me as much as i can

Why cant I take it during the day? Even if it is 50% less effective, ioculd

double the dose..

Any reasons not to?

From: Deidre Alejo

Reading the LDN website is beneficial.

Dosage for cancer is 4.5 mg. Most doctors don't know

about the " low dose " version of naltrexone and need

to be educated. If you have trouble with your doctor,

we have material and doctor lists which can help you.

I have now 2 doctors which are willing to prescribe

LDN for me but went through a series of emails with doctors

who didn't see the benefit. Education is the key.

http://www.low dose naltrexone.org/

Thankful I kept up the fight and found doctors who are eager to keep me

alive. Hope to see many at the LDN conference in October.

Dee

http://www.ldn4cancer.com

[Guest guest]

nataliemediumt writes:

You can just order this from the pharmacy in NYC then?

Irmat is very expensive. Skips is cheaper, even with the shipping.

[Guest guest]

Doubling the dose will do nothing. The reason it might not be as

effective taken during the day is related to the circadian rhythms of

the body. There is normally an endorphin surge around 4 am. The

earlier suppression of the LDN will produce a reactive increase in

endorphins timed to coincide with the natural pattern.

The only reason it would work at all taken during the day is that it

would still upregulate metenkephalin receptors which could produce G

arrest in cancer cells when metenkephalin attaches to those sites on

cancer cells.

Mike

VINCENT TOKATLIAN wrote:

>

> I took one pill...1.4 mg 2 nights in a row, but I am having trouble

> slleping....You suggested i get in me as much as i can

> Why cant I take it during the day? Even if it is 50% less effective,

> ioculd double the dose..

> Any reasons not to?

>

> .

>

>

[Guest guest]

I am not doubling the dose..its supposed to be 4.5 mg..but the doc had said due

to possible sleeping problems, start. with 1.5, and then gradually increase it

So what i meant was doubling the 1.5

From: Golden, D.C.

Doubling the dose will do nothing. The reason it might not be as

effective taken during the day is related to the circadian rhythms of

the body. There is normally an endorphin surge around 4 am. The

earlier suppression of the LDN will produce a reactive increase in

endorphins timed to coincide with the natural pattern.

The only reason it would work at all taken during the day is that it

would still upregulate metenkephalin receptors which could produce G

arrest in cancer cells when metenkephalin attaches to those sites on

cancer cells.

[Guest guest]

I have reported on LDN (Low Dose Naltrexone) in several past

newsletters. Suggestion: try a search at

http://www.fms-help.com/newsletters.htm

to see what other readers said about it.

Dom

>

> Has anyone tried this? I started to and then discovered because I was

> using tramadal, which has an opioid receptor I could not mix the two.

> Just haven't gotten back to it, so if anyone has some experience with

> it would like to hear about it.

>

> Manythanks and Happiest of Holidays to all. And try to take it easy!

>

[Guest guest]

Naloxone is a relative of Naltrexone, but what you need to know is LDN is a low dose of the standard supplied dose of Naltrexone. This normally has to be compounded by a reliable pharmacy that abides by specific formulas for fillers and fast acting - not extended release.

Please see the web sites for specific information. Here are a few:

http://www.ldners.org/

http://www.freewebs.com/crystalangel6267/index.htm

http://autoimmunedisease.suite101.com/article.cfm/low_dose_naltrexone_update

Following the recommended protocols yields the best results.

If LDN is unavailable in your area, it is available via the web.

You should receive many replies to your query and help.

Best of luck

Bob C

From: Antonia Sacca <alfa@...>Subject: [low dose naltrexone] Low Dose Naltrexonelow dose naltrexone Date: Tuesday, February 3, 2009, 12:20 AM

My fiance' was diagnosed with a rare/agresssive form of cancer, he has had surgeries and has had his lymph nodes removed from his groin area, there is currenty no cancer present in his body, however we are looking at all areas to ensure that he continues to remain in remission. Is this Low Dose Naltrexone that you discuss available to us in Australia? Do we have to speak to our doctors about it? Its such a coincidence because I was addicted to a codiene based pain killer for over 10 years and was taking high doses, and currently I am taking Suboxone which is Buprenorphine/ naloxone. Is that the same as naltrexone? Please advise if you have any comments or suggestionRegardsAntonia

[Guest guest]

you can get low dose naltrexone in australia.for cancer info and ldn

better join this group

LDN_4_cancer/

>

> My fiance' was diagnosed with a rare/agresssive form of cancer, he

has

> had surgeries and has had his lymph nodes removed from his groin

area,

> there is currenty no cancer present in his body, however we are

looking

> at all areas to ensure that he continues to remain in remission.

Is

> this Low Dose Naltrexone that you discuss available to us in

Australia?

> Do we have to speak to our doctors about it?

>

> Its such a coincidence because I was addicted to a codiene based

pain

> killer for over 10 years and was taking high doses, and currently

I am

> taking Suboxone which is Buprenorphine/naloxone. Is that the same

as

> naltrexone?

>

> Please advise if you have any comments or suggestion

>

> Regards

> Antonia

>

[Guest guest]

Hi ,

I am sorry to hear of your MS progressing, my partner has SPMS and was

on those awful beta interferon injections for a few years. Two days

every week (he had to inject weekly) he knew he was going to be ill.

It was awful to see. We found out about LDN in August and decided to

give that a try, coincidentally a letter arrived from his neuro saying

they couldn't do anything more for him and agreed for him to come off

the injections. However, his neuro supported him taking LDN, his GP

said if he got this letter from his neuro, he would be quite happy to

prescribe LDN. His neuro supported him taking LDN and wishes him the

best of luck but his GP changed his mind and told him he didn't have

time for him and to get out of his office. Needless to say an official

complaint has been made and he has since changed his GP! The main

reason in the UK is because it hasn't been clinically trialled, hence

proven safe, which is why it desperately needs to go to trials. Until

then, most GPs / Neuro's will not take the responsibility of

prescribing it, and as you say, a lot haven't heard of it, hence the

need to raise awareness.

However, I believe people's experiences with LDN is proof in itself and

the changes in my partner has been quite incredible. He was pretty

much wheelchair bound but now can walk on crutches. Use to have to use

a stair lift but just last week was able to climb the stairs! I don't

know how the MS effects you as everyone is different, but his balance

was way off, yet the other month he stood up and changed a light bulb!

I know these are all day to day things for your average person, but for

someone with SPMS it's such an achievement. He's regained a lot of

feeling back in his body, but will probably never get full use of his

right leg as the nerve damage is too bad. LDN will halt the

progression, and boost the immune system which is what you need. The

other medication may help but it is my belief, just for a short time.

I would seriously consider taking LDN. It's something we only wish we

knew about years ago. His neuro was aware of it but he wasn't given

the option out of all the conventional treatments. So a lot of time

was spent thinking 'if' and 'if' and 'if' followed by a bit of anger.

I am sure you will make the decision that's right for you, just thought

I'd share that with you.

Jayne

>

>

> I just had an appointment with my neuro and brought up LDN. His

> response was that he had not heard of it. I am a little reluctant

> to try under that response. He has just upgrade my MS from rrms to

> secondary ppms. His is stopping my Betaseron and putting on

> Novantrone. My first enfussion is next week. I see so many people

> using LDN and with the success that they are having. I have fax all

> the info I cound find to my neuro and see what he says. 5 days

> after my getting my first Novantrone I will see him again. Would

> like as my info that I can get to take to him.

>

[Guest guest]

While you're researching, and if you don't yet have a copy - I can email

the free LDN book 'Those who suffer much, know much', or you can obtain it

from casehealth.com.au

My name is Cris, and in 2001 I set-up a community service website to

collect and share health success stories in the hope of making the path to

health success shorter for others.

Many years ago, after receiving two patient stories about the successful

use of low doses of naltrexone in the treatment of MS, I became curious and

investigated further.

My first thought was that someone stood to make some money out of it, and

my second was that it was an anomaly - perhaps these patients didn't really

have MS and had been misdiagnosed?

I was wrong on both fronts.

I was fortunate to find Dr Gluck's site, join the LDN group to hear

the experiences of the many who'd been using LDN, and of course, meet the

very lovely Elsegood of LDN Research Trust in the UK.

Not only were the stories genuine, but no-one stood to gain financially. It

was all patient-driven, in the interest of telling others what was working

for them.

To cut a very long story short, there is a book available on

casehealth.com.au which contains a selection of truly inspiring patient

stories - and in keeping with my website philosophy and the altruistic

intent of all the contributors, it is available free of charge and can be

freely shared forward.

The book 'Those who suffer much, know much' features 29 case studies

attributing low dose naltrexone (LDN) with improved health.

Book Content:

20 Multiple Sclerosis case studies

2 HIV/AIDS case studies

1 Hepatitis B case study

1 Primary Lateral Sclerosis case study

2 Cancer case studies

2 Crohn's Disease case studies

1 Multiple Benefits case study

The book includes an explanatory article, and interviews with professionals

familiar with LDN - Dr. Gluck, Dr. Tom Gilhooly, Dr. Jaquelyn

McCandless, and Dr. Skip Lenz, Pharmacist - and is in the safest readily

available format, Adobe pdf.

Some who take LDN do not benefit at all, others notice lack of progression

and improved bladder control, and others minor or major symptom benefits -

so LDN is not for everyone, but everyone should at least be aware of it as

a treatment option,

Cris

PS Further story contributions are needed.

2a. Re: Low Dose Naltrexone

Posted by: " chelsea123dog " jaynecrocker@... chelsea123dog

Date: Tue Feb 3, 2009 5:39 am ((PST))

Hi ,

I am sorry to hear of your MS progressing, my partner has SPMS and was

on those awful beta interferon injections for a few years. Two days

every week (he had to inject weekly) he knew he was going to be ill.

It was awful to see. We found out about LDN in August and decided to

give that a try, coincidentally a letter arrived from his neuro saying

they couldn't do anything more for him and agreed for him to come off

the injections. However, his neuro supported him taking LDN, his GP

said if he got this letter from his neuro, he would be quite happy to

prescribe LDN. His neuro supported him taking LDN and wishes him the

best of luck but his GP changed his mind and told him he didn't have

time for him and to get out of his office. Needless to say an official

complaint has been made and he has since changed his GP! The main

reason in the UK is because it hasn't been clinically trialled, hence

proven safe, which is why it desperately needs to go to trials. Until

then, most GPs / Neuro's will not take the responsibility of

prescribing it, and as you say, a lot haven't heard of it, hence the

need to raise awareness.

However, I believe people's experiences with LDN is proof in itself and

the changes in my partner has been quite incredible. He was pretty

much wheelchair bound but now can walk on crutches. Use to have to use

a stair lift but just last week was able to climb the stairs! I don't

know how the MS effects you as everyone is different, but his balance

was way off, yet the other month he stood up and changed a light bulb!

I know these are all day to day things for your average person, but for

someone with SPMS it's such an achievement. He's regained a lot of

feeling back in his body, but will probably never get full use of his

right leg as the nerve damage is too bad. LDN will halt the

progression, and boost the immune system which is what you need. The

other medication may help but it is my belief, just for a short time.

I would seriously consider taking LDN. It's something we only wish we

knew about years ago. His neuro was aware of it but he wasn't given

the option out of all the conventional treatments. So a lot of time

was spent thinking 'if' and 'if' and 'if' followed by a bit of anger.

I am sure you will make the decision that's right for you, just thought

I'd share that with you.

Jayne

>

>

> I just had an appointment with my neuro and brought up LDN. His

> response was that he had not heard of it. I am a little reluctant

> to try under that response. He has just upgrade my MS from rrms to

> secondary ppms. His is stopping my Betaseron and putting on

> Novantrone. My first enfussion is next week. I see so many people

> using LDN and with the success that they are having. I have fax all

> the info I cound find to my neuro and see what he says. 5 days

> after my getting my first Novantrone I will see him again. Would

> like as my info that I can get to take to him.

[Guest guest]

Sheila

My emails to TPA seem to be rejected but I'm still receiving, there was some research I wanted to send on to you, hope I haven't done anything wrong.

Jane

No virus found in this outgoing message.Checked by AVG.Version: 7.5.557 / Virus Database: 270.11.13/1999 - Release Date: 13/03/2009 05:59

[Guest guest]

Well

- your last two messages have obviously got through Jane - so how come you

believe they are being rejected - and no, as far as I know, you have been a

good girl.

luv -

Sheila

Sheila

My emails to TPA seem to be rejected but I'm

still receiving, there was some research I wanted to send on to you, hope I

haven't done anything wrong.

Jane

No virus found in this outgoing message.

Checked by AVG.

Version: 7.5.557 / Virus Database: 270.11.13/1999 - Release Date: 13/03/2009 05:59

[Guest guest]

I have been trying to do a bit of research on this subject, unfortunately have

very little time. I found one person with several

autoimmune diseases who was taking it who said it did her no good

at all, but she didnt say specifically which disease she was targeting

Another person was on it for colitis and thought it was " wonderful stuff " , but

she had problems with underactive thyroid and it didnt

seem to have helped that

It is used mainly for MS in this country

http://www.ldnresearchtrust.org/

http://www.ahsta.com/

Ginny B

>

> HYPERLINK

> " http://www.low dose naltrexone.org/ " http://www.low dose naltrexone.org/

> Low-dose naltrexone holds great promise for the millions of people worldwide

> with autoimmune diseases or central nervous system disorders or who face a

> deadly cancer. Has anybody hard of this - it sounds too good to be true.

[Guest guest]

Hi Ginny,

Was that me? I hadn't take LDN for a few months (supply problem) during that

time was when I gained weight and had my bloods done.

I've just started taking it again, here's hoping it helps because my GP thinks

my symptoms are nothing to do with thyroid but depression and colitis (which

usually makes you lose weight).

I now have a copy (I didn't ask, they just came with a choose and book letter

for my gastro) of my blood test results.

My cholesterol is a bit on the high side, and creatinine is high. Surely

combined with a TSH of 3.76 and free T4 13.5 that means something is going on

with my thyroid.

This weight gain is just unexplainable. I even had vomiting bug and tonsilitis

in one month, barely ate. I put on weight!

>

> I have been trying to do a bit of research on this subject, unfortunately have

very little time. I found one person with several

> autoimmune diseases who was taking it who said it did her no good

> at all, but she didnt say specifically which disease she was targeting

> Another person was on it for colitis and thought it was " wonderful stuff " , but

she had problems with underactive thyroid and it didnt

> seem to have helped that

>

> It is used mainly for MS in this country

>

> http://www.ldnresearchtrust.org/

> http://www.ahsta.com/

>

> Ginny B

>

>

> >

> > HYPERLINK

> > " http://www.low dose naltrexone.org/ " http://www.low dose naltrexone.org/

> > Low-dose naltrexone holds great promise for the millions of people worldwide

> > with autoimmune diseases or central nervous system disorders or who face a

> > deadly cancer. Has anybody hard of this - it sounds too good to be true.

>

[Guest guest]

I'm going to email my gp and ask again if he's sure my thyroid is normal. Are

there any good links, you know peer reviewed stuff I can send?

>

> Hi Ginny,

>

> Was that me? I hadn't take LDN for a few months (supply problem) during that

time was when I gained weight and had my bloods done.

> I've just started taking it again, here's hoping it helps because my GP thinks

my symptoms are nothing to do with thyroid but depression and colitis (which

usually makes you lose weight).

[Edit Abbrev Mod]

[Guest guest]

Hello Group,

does anyone know of a doctor that prescribes LDN in Tucson, Arizona?

thank you,

________________________________

From: vinnylid <vinnylid@...>

rheumatic

Sent: Saturday, July 4, 2009 9:30:11 AM

Subject: rheumatic Low Dose Naltrexone

LDN is not considered a stand alone treatment and is not a short term pain

reliever. It is used to enhance our immune system to help fight the disease. If

we are fighting a " cell wall deficient Mycoplasma bacteria " then it is important

to have the infection under control before starting LDN. My Psoriatic Arthritis

attack started in Dec, 2007 and I started 100mg twice daily Minocycline in June,

2008. I also used 50mg of Diclofenac daily. With my pain and symtoms under

control, I started working on immune side of my disease by also adding LDN to my

treatment on Feb 24, 2009. Since that time I have been reducing the amount of

Minocycline I use to the point that I have been off it for 3 weeks and only use

Diclofenac occasionally to treat a specific pain issue. I buy 50mg Naltrexone

pills and dilute one 50mg pill in 50ml of water and take 4.5ml every night a

9pm. After some initial sleep disruption from LDN, I now sleep better than I had

previously. I also

take natural antibiotics herbs and digestive enzymes.

vinnylid

[Guest guest]

Hi enkai,

I had one of those days ~ thinking laterally...

came to the conclusion that banning morphine was a bad deal....

babies and bathwater.....

yer see, laudanum was the choice medicine for many centuries ~ when along came the British Empire and started abusing it......

now, it's citalopram instead.......very much more effective and (was) profitable ....lots of kicking and screaming that they wanted to re-patent the pure optically active isomer escitalopram......no bloody wonder, ............it's addictive, just like the racemic mixture (citalopram) >> ... bad as(s) cocaine !!!

oh, so no problem then.....only available on 'script.

ten years for 'dealing' in citalopram......twenty more like....

now tell me, what's the difference between one drug that relieves pain and is addictive ......and another drug that relieves schizophrenia, bipolar disorder, SAD, anorexia, major depression....and is addictive....but is active at the

5HTR2A locus in the genome ?

Good question

Bob

Answers in plain brown envelopes please :-)

>> Hi > > Bob, the other day I saw in one of your messages that you are researching LDN at the > moment. > > Just wondering, what do you make of it with regards to treating Hashi's? Can you see any > potential problems later down the road for people who start taking it? > > I'm quite interested in the drug as I have two autoimmune diseases, but am a bit hesitant > to try it at the moment as it is still in it's testing phases.> > Cheers> Enkai> > ps. anyone else's opinions are welcome too!>

[Guest guest]

I started LDN 10 days ago, having good results so far. I am updating my

experiences as they go on . There is info in the files section. The official

site for LDN is www.low dose naltrexone.org There is also a couple of sites

dedicated to LDN. I would encourage you to research.

I would suggest you use the word 'trial' of LDN as I get the impression that

docs are OK with a 'trial' of something, whereas they are not comfortable doing

anything that is not standard treatment.

LDN_Users/

http://tinyurl.com/ldn-side-effects

F

>

> Hi.

> Has anybody out there had any personal experience with Low Dose

> Naltrexone? I have heard many good reports about it and am considering

> asking my Crohn's specialist (I have an appt on 31st July) if I can go

> on it. Although I would be taking it for Crohn's disease, I have heard

> it is also very good for Fatigue and that people are actually using it

> Lv Renny

>

[Guest guest]

Read about it in the FILES section of this forum web site Renny.

Any questions after you have read this, just shout. (in Oz) has started a

course of this treatment and is keeping a diary, also accessible in the Low

Dose Naltrexone FOLDER.

Luv - Sheila

Has anybody out there had any personal experience with Low Dose Naltrexone? I

have heard many good reports about it and am considering asking my Crohn's

specialist (I have an appt on 31st July) if I can go on it. Although I would be

taking it for Crohn's disease, I have heard it is also very good for Fatigue

and that people are actually using it for CFS, is this true?

Just to refresh your memories, I have been on Prednisolone for Crohn's since

1995, I am down to 1.5mg now but it is suspected my adrenals are damaged (I had

a 'Syacthen' test last Fri) and, I was wondering if LDN would help.

I would be interested to hear of any experiences with this drug. Cheers

Lv Renny

Checked by

AVG - www.avg.com

Version: 8.5.375 / Virus Database: 270.13.3/2217 - Release Date: 07/05/09

17:54:00

[Guest guest]

crystal has a list of prescribing doctors

>

> Hello everyone.  I'm new to this form of communication.  I would like to get a

scrip for ldn, but neither my nuerologist or family doctor will prescribe it for

me. any ideas,  I have MS, diagnosed in 2001 and on disability.  I have no idea

if medicaid would pay for it or not.  Anyone have any ideas?  thanks 

arkansasron

>

[Guest guest]

Interesting.  I only know of naltrexone as a drug that's used to reduce

cravings in people who are addicted to drugs or alcohol. 

 Joanna Hoelscher

[Guest guest]

I am using Low Dose Naltrexone(4.5mg) and minocycline antibiotic protocol to

treat psoriatic arthritis. I got immediate relief from pain using 100mg twice

daily minocycline and 50mg diclofenac. The LDN has allowed me to cut back on the

minocycline level and eliminate the diclofenac. I am back to playing golf again

and leading a normal life for a 65 year old man.

vinnylid

--- Joanna Hoelscher <joannahoelscher@...> wrote:

<<Interesting.  I only know of naltrexone as a drug that's used to reduce

cravings in people who are addicted to drugs or alcohol.>> 

[Guest guest]

Just checked my BC/BS Formulary which lists drugs by " classification " . After

reading, vinnylid, that you - too - are being prescribed naltexone - I thought

it might be in the Analgesics category, as are methadone and suboxone, both used

in the treatment of heroin addiction; but it's not, Naltrexone is listed in the

category called " Antidote, Deterrent, and Toxilogic Agents " which includes, for

the most part, drugs that are used to help smokers quit, i.e. chantal, nicotrol,

etc.

It is always of interest to me when I find drugs designed for one thing being

used - successfully - for something else. I would guess that naltrexone is not

a drug that a lot of rheumatologists would prescribe (too " unconventional " ,

perhaps); so good for you both for having doctors who think outside the box.

This kind of information is always useful.

Joanna Hoelscher

[Guest guest]

Hi vinnylid,

would you please give us more information ,how long ago you started to take

LDN, and if it has been effective for clearing the skin too - any side

effects? I am going to ask my MD to prescribe it for me. It seems like a

miracle.

wish you the very best of health,

soudi

[Guest guest]

thank your for the info.

Love, Live, and Laugh

________________________________

From: Noreen <noreenelaine@...>

cures for AIDS

Sent: Tue, September 28, 2010 8:44:02 AM

Subject: Low Dose Naltrexone

Am reading posts about cutting up 50mg LDN. Also, I believe that there is a

liquid form too. However, I would suggest that one simply order it from one of

the approved pharmacies (if one can get a prescription) because the " fillers " in

the product can make a difference to some and the time-release issue is

important too. I have used Skip's Pharmacy in Florida for years. The product

averages about $22.00/month, including shipping. Why take the chance of not

getting it right? Any approved pharmacy on the low dose naltrexone.org website

would make it correct.

If one is having trouble getting the prescription, join the LDN support group on

, Crystal keeps a list of doctors by state, who will prescribe it.

Remember, LDN is helping so many of us, but it too is not a cure-for-all, but I

believe that it is keeping the opportunistic diseases away, since my CD4's

generally remain under 100 and I don't take HAART nor antibiotics.

One quick note, I found that even in the low dosage of 4.5mg, I cannot drink

wine, etc. as it makes me sick. The higher dosage of 50mg is used for treating

drug/alcohol addiction. This may vary from person to person in the lower dosage.

[Guest guest]

It is a prescription and mine is from a compounding pharmacy. My integrative

doctor prescribed it. Also, my immunologist (Dr. Rey/Klimas) highly recommends

it. I've taken it for a year now - am on 4.5 mg (the max). It has taken my pain

from an unbearable level to a much tolerable level. I highly recommend giving it

a try.

Joy

>

> Where do you get ldn? I thought you had to get it out of the usa? joyce

>