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mucormycosis

Rhinocerebral mucormycosis

Rhinocerebral mucormycosis is an infection of the nose, eyes, and brain. The

fungus destroys the tissue of the nasal passages, sinuses, or hard palate,

producing a black or pus-filled discharge and visible patches of dying tissue.

The patient will typically have fever, pain, and forward bulging of the eyes

(proptosis). The fungus then invades the tissues around the eye socket and

eventually the brain. At that point the patient may have convulsions or

paralysis on one side of the body.

Causes and symptoms

Mucormycosis is caused by fungi of several different species, including Mucor,

Rhizopus, Absidia, and Rhizomucor. When these organisms gain access to the

mucous membranes of the patient's nose or lungs, they multiply rapidly and

invade the nearby blood vessels. The fungi destroy soft tissue and bone, as well

as the walls of blood vessels.

The early symptoms of rhinocerebral mucormycosis include fever, sinus pain,

headache, and cellulitis. As the fungus reaches the eye tissues, the patient

develops dilated pupils, drooping eyelids, a bulging eye, and eventually

hemorrhage of the blood vessels in the brain—causing convulsions, partial

paralysis, and death.

The symptoms of pulmonary mucormycosis include fever and difficulty breathing,

with eventual bleeding from the lungs.

The symptoms of gastrointestinal mucormycosis are not unique to the disease,

which may complicate diagnosis. Patients typically complain of pressure or pain

in the abdomen, nausea, and vomiting.

http://medical-dictionary.thefreedictionary.com/mucormycosis

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