Re: Inhalational mold toxicity: fact or fiction? Emil Bardana

[Guest guest]

well, if I met the bandana man face to face, I'd show him some psycho.

>

> Everyone should enjoy reading this. I don't recall seeing it before.

>

> May

> May Indoor Air Investigations LLC

> Tyngsborough, MA

> www.mayindoorair.com

> 978-649-1055

>

>

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> Inhalational mold toxicity: fact or fiction? a clinical review of 50 cases

> Barzin Khalili, MD , Emil J. Bardana Jr, MD

>

> Received 27 January 2005; accepted 28 March 2005.

>

> Background

>

> Three well-accepted mechanisms of mold-induced disease exist: allergy,

> infection, and oral toxicosis. Epidemiologic studies suggest a fourth

> category described as a transient aeroirritation effect. Toxic mold

> syndrome or inhalational toxicity continues to cause public concern

> despite a lack of scientific evidence that supports its existence.

>

> Objectives

>

> To conduct a retrospective review of 50 cases of purported

> mold-induced toxic effects and identify unrecognized conditions that

> could explain presenting symptoms; to characterize a subgroup with a

> symptom complex suggestive of an aeroirritation-mediated mechanism and

> compare this group to other diagnostic categories, such as sick

> building syndrome and idiopathic chemical intolerance; and to discuss

> the evolution of toxic mold syndrome from a clinical perspective.

>

> Methods

>

> Eighty-two consecutive medical evaluations were analyzed of which 50

> met inclusion criteria. These cases were critically reviewed and

> underwent data extraction of 23 variables, including demographic data,

> patient symptoms, laboratory, imaging, and pulmonary function test

> results, and an evaluation of medical diagnoses supported by medical

> record review, examination, and/or test results.

>

> Results

>

> Upper respiratory tract, lower respiratory tract, systemic, and

> neurocognitive symptoms were reported in 80%, 94%, 74%, and 84% of

> patients, respectively. Thirty patients had evidence of

> non?mold-related conditions that explained their presenting

> complaints. Two patients had evidence of allergy to mold allergens,

> whereas 1 patient exhibited mold-induced psychosis best described as

> toxic agoraphobia. Seventeen patients displayed a symptom complex that

> could be postulated to be caused by a transient mold-induced

> aeroirritation.

>

> Conclusion

>

> The clinical presentation of patients with perceived mold-induced

> toxic effects is characterized by a disparate constellation of

> symptoms. Close scrutiny revealed a number of preexisting diagnoses

> that could plausibly explain presenting symptoms. The pathogenesis of

> aeroirritation implies completely transient symptoms linked to

> exposures at the incriminated site. Toxic mold syndrome represents the

> furtive evolution of aeroirritation from a transient to permanent

> symptom complex in patients with a psychogenic predisposition. In this

> respect, the core symptoms of toxic mold syndrome and their gradual

> transition to chronic symptoms related to nonspecific environmental

> fragrances and irritants appear to mimic what has been observed with

> other pseudodiagnostic categories, such as sick building syndrome and

> idiopathic chemical intolerance.

>

[Guest guest]

Hi Jeff,

I believe this was posted before, being a 2005 paper. Another interesting

paper seems to argue the other way, and is available in full on the web at:

http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijto/vol5n2/mold.xml

The validity of the environmental neurotoxic effects of toxigenic molds and

mycotoxins published on The Internet Journal of Toxicology. 2008

Perhaps this article may be of help in discrediting Bardana in court.

Inhalational mold toxicity: fact or fiction? Emil Bardana

Posted by: " jeff@... " jeff@... jmhiaq

Date: Fri Apr 23, 2010 6:07 pm ((PDT))

Everyone should enjoy reading this. I don't recall seeing it before.

May

May Indoor Air Investigations LLC

Tyngsborough, MA

www.mayindoorair.com

978-649-1055

-------------------------------------------------------------------------------

Inhalational mold toxicity: fact or fiction? a clinical review of 50 cases

Barzin Khalili, MD , Emil J. Bardana Jr, MD

Received 27 January 2005; accepted 28 March 2005.

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