Re: Mucosal Damage and Neutropenia Are Required for Candida albicans Dissemination

[Guest guest]

Our study provides new insights into the process of how a typically harmless

microorganism inhabiting the GI tract can cause severe invasive disease once

critical components of the host immune system are compromised.

Mucosal Damage and Neutropenia Are Required for Candida albicans Dissemination

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http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.0040035

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> > Curr Opin Microbiol. 2010 Aug;13(4):409-15. Epub 2010 Jun 2.

> Interaction of phagocytes with filamentous fungi.

> http://www.ncbi.nlm.nih.gov/pubmed/20627805

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> Essential Role for Neutrophils but not Alveolar Macrophages at Early Time

Points

> following Aspergillus fumigatus Infection

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745295/?report=abstract & tool=pmcent\

rez

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> Production of extracellular traps against Aspergillus fumigatus in vitro and

in

> infected lung tissue is dependent on invading neutrophils and influenced by

> hydrophobin RodA

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http://www.ncbi.nlm.nih.gov/pubmed/20442864?ordinalpos=1 & itool=PPMCLayout.PPMCAp\

pController.PPMCArticlePage.PPMCPubmedRA & linkpos=3

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