Re: amine intolerance & gut dysbiosis--Dr Thrasher

[Guest guest]

Could be wrong, but I always thought it was the pancreas that was the main

organ adversely impacted by amine substances in some people and that's

what causes the digestive problems. Don't they prescribe pancreatic enzymes to

help with absorption of amines? I could be totally off base. Do you

know, Jack?

Sharon

In a message dated 11/13/2010 12:28:14 P.M. Pacific Standard Time,

toxicologist1@... writes:

Amy: the problem here is that the medical profession (notice no capital

letters) worldwide refuses to recognize the problem your daughters are

having. Dysbiosis can lead to intestinal problems as you suspect, which can

affect individuals systemically.

If you check the web site of Genova Diagnostics I believe the lab has

testing for dysbiosis.

If your daughters have abnormal intestinal flora and have had chronic

infections from yeast, fungi and/or bacteria, you may be battling the issue of

biofilms. We have touched upon the biofilms in this forum. Biofilms protect

sessile microorganisms that have colonized mucosa of the respiratory and

intestinal tract from environmental insults, e.g. antibiotics antifungals.

This condition sets up a chronic infectious state. If this is the case, then

you will have to search the web for solutions to breaking down the

biofilms.

Finally, one method that I read about was taking the bacteria flora from a

normal person (one that does not have intestinal symptoms) and inoculating

the flora into the ill person. There is a posting on the web of an

internist who did this procedure on a woman with chronic intestinal problems.

He

took the flora from the healthy husband. The ill woman returned to normal

intestinal functions with a few days after the transplant. You may want to

search the web for this information. Unfortunately I failed to keep the news

release on the procedure. Perhaps someone on this forum kept the

information.

----- Original Message -----

From: amybreau

_ _ (mailto: )

Sent: Saturday, November 13, 2010 5:40 AM

Subject: [] amine intolerance & gut dysbiosis--Dr Thrasher

Dr. Thrasher,

My girls both have amine intolerance which causes major sleep, stool and

behavior problems. On a low amine diet they are healthy and symptom free. I

assumed this stemmed from a genetic metabolic disorder, but recently read

that amine intolerance could be caused by gut dysbiosis, because some

bacteria or fungi that colonize the gut produce amines. This could raise amine

levels in the body to the point where dietary amines put the person over their

threshold.

My older daughter sees a biomed doc who did general testing, finding

markers of gut inflammation and organic acids suggesting yeast or other

colonization. She's on MCT oil and high dose probiotics.

I'm wondering if there is more specific testing and treatment we could do,

either of stool or the house, that might shed some light. Are there

certain microbes you know of that could produce high levels of amines?

You mentioned bulk testing for mold types and gram + or - bacteria

previously. Do we need visible microbe growth to bulk test? We don't have

visible

mold--my concern is our heating ducts. They've been thoroughly cleaned but

I could take off vent covers and swab.

Thank you for any thoughts on this,

Amy

[Guest guest]

Amy: the problem here is that the medical profession (notice no capital

letters) worldwide refuses to recognize the problem your daughters are having.

Dysbiosis can lead to intestinal problems as you suspect, which can affect

individuals systemically.

If you check the web site of Genova Diagnostics I believe the lab has testing

for dysbiosis.

If your daughters have abnormal intestinal flora and have had chronic infections

from yeast, fungi and/or bacteria, you may be battling the issue of biofilms.

We have touched upon the biofilms in this forum. Biofilms protect sessile

microorganisms that have colonized mucosa of the respiratory and intestinal

tract from environmental insults, e.g. antibiotics antifungals. This condition

sets up a chronic infectious state. If this is the case, then you will have to

search the web for solutions to breaking down the biofilms.

Finally, one method that I read about was taking the bacteria flora from a

normal person (one that does not have intestinal symptoms) and inoculating the

flora into the ill person. There is a posting on the web of an internist who

did this procedure on a woman with chronic intestinal problems. He took the

flora from the healthy husband. The ill woman returned to normal intestinal

functions with a few days after the transplant. You may want to search the web

for this information. Unfortunately I failed to keep the news release on the

procedure. Perhaps someone on this forum kept the information.

[] amine intolerance & gut dysbiosis--Dr Thrasher

Dr. Thrasher,

My girls both have amine intolerance which causes major sleep, stool and

behavior problems. On a low amine diet they are healthy and symptom free. I

assumed this stemmed from a genetic metabolic disorder, but recently read that

amine intolerance could be caused by gut dysbiosis, because some bacteria or

fungi that colonize the gut produce amines. This could raise amine levels in the

body to the point where dietary amines put the person over their threshold.

My older daughter sees a biomed doc who did general testing, finding markers

of gut inflammation and organic acids suggesting yeast or other colonization.

She's on MCT oil and high dose probiotics.

I'm wondering if there is more specific testing and treatment we could do,

either of stool or the house, that might shed some light. Are there certain

microbes you know of that could produce high levels of amines?

You mentioned bulk testing for mold types and gram + or - bacteria previously.

Do we need visible microbe growth to bulk test? We don't have visible mold--my

concern is our heating ducts. They've been thoroughly cleaned but I could take

off vent covers and swab.

Thank you for any thoughts on this,

Amy

[Guest guest]

Maybe that is why I test so low in amino acids. They are amines. I say I am

following a high protein, low carb diet but my blood test came out very low in

amino acids which couldn't be more important to everything as protein is the

building block of almost every process. This was a test done early on in my

illness and I don't know what test would look like now. I don't eat 'alot' but

I was trying to have protein at every meal so was very surprised by results.

She diagnosed me with leaky gut. Actually that is about time I tried CSM and

could not keep it down...so gut probably in very bad shape. I can take CSM

now.

>

> Could be wrong, but I always thought it was the pancreas that was the main

> organ adversely impacted by amine substances in some people and that's

> what causes the digestive problems. Don't they prescribe pancreatic enzymes

to

> help with absorption of amines? I could be totally off base. Do you

> know, Jack?

>

> Sharon

>

>