K, this got me to thinking

[Guest guest]

you know that article you posted about MCS, it said that you only react to what

you exposed to that you become reactive to. I just dont know how thats possable.

seems you would become reactive to anything that

has any properties of/or family of a chemical that you were exposed to.

disorders of taste and smell/olfactory

The chemical compounds that are inspired in the air will pass through the nasal

vault, but only 15% of inspired air passes by the olfactory mucosa with regular

breathing. During a sniff, however, a much higher percentage of inspired air is

exposed to the neuroepithelium. Along the ciliated ends of the ORNs are the

olfactory receptors capable of binding the odorants in the air and signaling the

brain of the odor's presence. There are over 1000 genes for the odorant

receptors, 3% of our genome, but due to chemical similarity, receptor

specificity or unspecificity, concentration, binding affinity, solubility, and

exposure time, we are able to process many more than these 1000 odors. The

odorants must traverse the mucus overlying the epithelium, and hydrophobic

compounds must bind transport proteins to carry them to the olfactory receptors.

The binding of the odorant to the olfactory receptor causes activation of the

G-protein class olfactory receptor, leading to influx of Ca2+ via c-AMP pathways

which results in depolarization of the ORN and neuronal communication. The

common chemosensory pathways are separate from those of CN I, as these are

mediated by the first and second division of CN V. Reflexes such and sneezing,

breath holding in the face of noxious odors, and reaction to ammonia are handled

by this pathway.

Toxin induced olfactory loss is due to noxious chemicals inhaled that result in

direct damage to the neuroepithelium, alterations in the mucus layer, and

ingrowth of respiratory mucosa. There are many toxins that can lead to

olfactory loss, so precautionary safety measures should be used to protect

against this problem.

http://www8.utsouthwestern.edu/utsw/cda/dept28151/files/289930.html