Guest guest Posted January 15, 2010 Report Share Posted January 15, 2010 These papers bug me. They never define what constitutes " immunocompromised " . They never state WHY they are able to detect mold in those they arbitrarily decide are " immunocompromised " , but WHY they can't detect mold in those they arbitrarily decide are immunocompetent. Infectious Diseases in Clinical Practice: January 2010 - Volume 18 - Issue 1 - pp 7-15 doi: 10.1097/IPC.0b013e3181bf62e7 Review Articles Combination Antifungal Therapy for Invasive Mold Infections Involving Polyenes: A Case Report and Brief Review of the Literature Chaux, E. MD (javascript:showHide('ej-article-box-text1', 'img1')) Abstract Invasive fungal infections (IFIs) are a significant cause of morbidity and mortality in severely immunocompromised hosts. There are now several new treatment options, including lipid forms of amphotericin B, azoles, and echinocandins, with improved tolerability profiles and novel mechanisms of action compared with conventional amphotericin B. Despite the expanding antifungal armamentarium, IFIs remain a common problem in patients at risk for invasive mycoses. The past 2 decades have seen an increase in the spectrum of opportunistic pathogens, including difficult-to-treat mold infections. The changing epidemiology of IFIs may be due to several factors, such as advances in therapy (new aggressive forms of immunosuppression and increased transplantation procedures) and emergence of resistance to antifungal drugs. The early diagnosis and treatment of patients with invasive infections present a significant challenge. This review will discuss epidemiological shifts, current therapeutic strategies to treat IFIs, and combination antifungal therapy with polyenes for the treatment of invasive mold infections. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2010 Report Share Posted January 16, 2010 For one thing, the increase in number of pharmaceutical drugs people take that have side effects of suppressing the immune system, and then the obvious to us, mycotoxin or endotoxin suppression, which I guess you are alluding to. >> > These papers bug me. They never define what constitutes > " immunocompromised " . They never state WHY they are able to detect mold in those they > arbitrarily decide are " immunocompromised " , but WHY they can't detect mold in > those they arbitrarily decide are immunocompetent. > > > Infectious Diseases in Clinical Practice: > January 2010 - Volume 18 - Issue 1 - pp 7-15 > doi: 10.1097/IPC.0b013e3181bf62e7 > Review Articles > > Combination Antifungal Therapy for Invasive Mold Infections Involving > Polyenes: A Case Report and Brief Review of the Literature > Chaux, E. MD > > > (javascript:showHide('ej-article-box-text1', 'img1')) > Abstract > > > Invasive fungal infections (IFIs) are a significant cause of morbidity and > mortality in severely immunocompromised hosts. There are now several new > treatment options, including lipid forms of amphotericin B, azoles, and > echinocandins, with improved tolerability profiles and novel mechanisms of > action compared with conventional amphotericin B. Despite the expanding > antifungal armamentarium, IFIs remain a common problem in patients at risk for > invasive mycoses. The past 2 decades have seen an increase in the spectrum of > opportunistic pathogens, including difficult-to-treat mold infections. The > changing epidemiology of IFIs may be due to several factors, such as > advances in therapy (new aggressive forms of immunosuppression and increased > transplantation procedures) and emergence of resistance to antifungal drugs. The > early diagnosis and treatment of patients with invasive infections present > a significant challenge. This review will discuss epidemiological shifts, > current therapeutic strategies to treat IFIs, and combination antifungal > therapy with polyenes for the treatment of invasive mold infections. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2010 Report Share Posted January 16, 2010 One doctor told me years ago that I was borderline immunosuppressed. Told me yeast wouldn't hurt me, and go on low carb diet and sent me on my way. No next appointment. Now that I have no insurance can't get the care. My doctor only charged me 25.00 at my last appointment. The older doctor retired-- and this one seems to know more but can't afford it. Just doesn't seem right. Are there any links for this paper? > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2010 Report Share Posted January 16, 2010 This shouldn't be the case in this country. Not one person deserves to be denied medical care - and equal care. I have to wait till the 1st of the month if I want to change doctors and my opthalmologist doesn't take my plan. All of this political crap about health is nothing more than that - crap! No doubt in my mind that the world is being culled. Barth www.presenting.net/sbs/sbs.html SUBMIT YOUR DOCTOR: www.presenting.net/sbs/molddoctors.html --- l> One doctor told me years ago that I was borderline immunosuppressed. Told me yeast wouldn't hurt me, and go on low carb diet and sent me on my way. No next appointment. Now that I have no l> insurance can't get the care. My doctor only charged me 25.00 at my last appointment. The older doctor retired-- and this one seems to know more but can't afford it. Just doesn't seem right. Are l> there any links for this paper? l> >> >> Quote Link to comment Share on other sites More sharing options...
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