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Infectious Diseases in Clinical Practice Antifungal Therapy for Invasive Mold

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These papers bug me. They never define what constitutes

" immunocompromised " . They never state WHY they are able to detect mold in

those they

arbitrarily decide are " immunocompromised " , but WHY they can't detect mold in

those they arbitrarily decide are immunocompetent.

Infectious Diseases in Clinical Practice:

January 2010 - Volume 18 - Issue 1 - pp 7-15

doi: 10.1097/IPC.0b013e3181bf62e7

Review Articles

Combination Antifungal Therapy for Invasive Mold Infections Involving

Polyenes: A Case Report and Brief Review of the Literature

Chaux, E. MD

(javascript:showHide('ej-article-box-text1', 'img1'))

Abstract

Invasive fungal infections (IFIs) are a significant cause of morbidity and

mortality in severely immunocompromised hosts. There are now several new

treatment options, including lipid forms of amphotericin B, azoles, and

echinocandins, with improved tolerability profiles and novel mechanisms of

action compared with conventional amphotericin B. Despite the expanding

antifungal armamentarium, IFIs remain a common problem in patients at risk for

invasive mycoses. The past 2 decades have seen an increase in the spectrum of

opportunistic pathogens, including difficult-to-treat mold infections. The

changing epidemiology of IFIs may be due to several factors, such as

advances in therapy (new aggressive forms of immunosuppression and increased

transplantation procedures) and emergence of resistance to antifungal drugs.

The

early diagnosis and treatment of patients with invasive infections present

a significant challenge. This review will discuss epidemiological shifts,

current therapeutic strategies to treat IFIs, and combination antifungal

therapy with polyenes for the treatment of invasive mold infections.

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For one thing, the increase in number of pharmaceutical drugs people take that

have side effects of suppressing the immune system, and then the obvious to us,

mycotoxin or endotoxin suppression, which I guess you are alluding to.

>>

> These papers bug me. They never define what constitutes

> " immunocompromised " . They never state WHY they are able to detect mold in

those they

> arbitrarily decide are " immunocompromised " , but WHY they can't detect mold in

> those they arbitrarily decide are immunocompetent.

>

>

> Infectious Diseases in Clinical Practice:

> January 2010 - Volume 18 - Issue 1 - pp 7-15

> doi: 10.1097/IPC.0b013e3181bf62e7

> Review Articles

>

> Combination Antifungal Therapy for Invasive Mold Infections Involving

> Polyenes: A Case Report and Brief Review of the Literature

> Chaux, E. MD

>

>

> (javascript:showHide('ej-article-box-text1', 'img1'))

> Abstract

>

>

> Invasive fungal infections (IFIs) are a significant cause of morbidity and

> mortality in severely immunocompromised hosts. There are now several new

> treatment options, including lipid forms of amphotericin B, azoles, and

> echinocandins, with improved tolerability profiles and novel mechanisms of

> action compared with conventional amphotericin B. Despite the expanding

> antifungal armamentarium, IFIs remain a common problem in patients at risk for

> invasive mycoses. The past 2 decades have seen an increase in the spectrum of

> opportunistic pathogens, including difficult-to-treat mold infections. The

> changing epidemiology of IFIs may be due to several factors, such as

> advances in therapy (new aggressive forms of immunosuppression and increased

> transplantation procedures) and emergence of resistance to antifungal drugs.

The

> early diagnosis and treatment of patients with invasive infections present

> a significant challenge. This review will discuss epidemiological shifts,

> current therapeutic strategies to treat IFIs, and combination antifungal

> therapy with polyenes for the treatment of invasive mold infections.

>

>

>

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One doctor told me years ago that I was borderline immunosuppressed. Told me

yeast wouldn't hurt me, and go on low carb diet and sent me on my way. No next

appointment. Now that I have no insurance can't get the care. My doctor only

charged me 25.00 at my last appointment. The older doctor retired-- and this one

seems to know more but can't afford it. Just doesn't seem right. Are there any

links for this paper?

>

>

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This shouldn't be the case in this country. Not one person deserves to

be denied medical care - and equal care. I have to wait till the 1st

of the month if I want to change doctors and my opthalmologist doesn't

take my plan. All of this political crap about health is nothing more

than that - crap! No doubt in my mind that the world is being culled.

Barth

www.presenting.net/sbs/sbs.html

SUBMIT YOUR DOCTOR: www.presenting.net/sbs/molddoctors.html

---

l> One doctor told me years ago that I was borderline immunosuppressed. Told me

yeast wouldn't hurt me, and go on low carb diet and sent me on my way. No next

appointment. Now that I have no

l> insurance can't get the care. My doctor only charged me 25.00 at my last

appointment. The older doctor retired-- and this one seems to know more but

can't afford it. Just doesn't seem right. Are

l> there any links for this paper?

l>

>>

>>

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