Guest guest Posted March 10, 2011 Report Share Posted March 10, 2011 The Use of Isolated Human Lymphocytes in Mycotoxin Cytotoxicity Testing All mycotoxin standards evaluated in this study were toxic to the human lymphocytes The variation of the individual's lymphocytes sensitivity to the tested mycotoxins in this study (DON, FB1 and OTA) was found to be negligible, as no significant difference was observed among the three donors. However, potential differences in in vivo exposures of lymphocytes to toxins must take into account individual differences such as the uptake, metabolism, combined effects of the toxins, the extent of exposure (duration or dose) and other factors such as age, gender, nutritional status, as well as the physiological state of the affected individuals. http://mdpi.org/ijms/papers/i9081515.pdf Quote Link to comment Share on other sites More sharing options...
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