Vaccines and neonatal immune development

[Guest guest]

Excellent (I missed this last year when it came out, as I was

traveling). Goes along well with Dr. Blaylock's video

(watch after you read the

below)

Visit 's blog for so much more..........................

Vaccines and neonatal immune development - 3 parts

http://www.beyondconformity.org.nz/BlogRetrieve.aspx?PostID=72027 & A=SearchResult & SearchID=4989767 & ObjectID=72027 & ObjectType=55

- Monday, May 23, 2011

(Series, Part 1 of 3) The Scientist recently

published an

article about

Dr Wallace who is head of a new unit called the Center for

Mitochondrial and Epigenomic Medicine, at the Children’s Hospital of

Philadelphia. Dr Wallace believes that “Every one of the diseases

we can’t solve is absolutely logical if we put energy at the

center,” ... “I believed that in 1970 and I believe it

now.” So what’s a mitochondria? If you don’t know,

this book might be one of the most important books you read in your

life. Use “Click to look inside” and the first two chapters which are

available free, will show you why mitochondria are so important.

Mitochondria, are intimately involved with your immune system, and if

your immune system isn’t working properly, neither will your

mitochondria. Dr Wallace has TWO problems in his new mitochondrial

research Center at the Children’s Hospital of Philadelphia, which I

believe will be insurmountable:

1) Dr Offit (vaccines and autism).

2) Dr Offit's echo, Arthur L Caplan, Ph. D. ( the Emmanuel and

Hart Professor of Bioethics and director of the Center for Bioethics at

the University of Pennsylvania). who says " The scientific

case for the importance of vaccines is overwhelming and beyond any

dispute (and most worries about safety rest on

fear and lies ). "

It's my bet, that Dr Wallace has already been instructed to stay away

from vaccines, or the impact of vaccines on the development of

mitochondrial dysfunction. Mitochondrial dysfunction will always be

consigned to the “cause” of vaccine reactions, never the

result of a vaccine's administration, because so many medical people

consider mitochondrial disorders to be genetic, not

" epigenetic " (affected by lifestyle).

If ... Dr Wallace believes autism has something to do with mitochondrial

disorders, then he needs to ask “why and how?” - or " what causes the

mitochondria to suddenly go wrong? "

alternatively, Dr. Wallace would have to seriously examine two issues

that have only recently received the attention they deserve:

1) The development of the neonatal immune system,

2) Epigenetic effects on vaccines on the developing neonatal immune

system.

Dr Wallace will also need to study

Dr Terry Wahl's

case, and see how when faced with a multiple sclerosis death sentence,

she set about righting

her mitochondria, and succeeded in doing so by good nutrition - a

topic that most allopathic physicians are fairly ignorant about.

Last but not least, Dr Wallace needs to compare the health of fully

vaccinated adults with never vaccinated

adults.

The research starting point, is pregnant mothers and babies. In

particular, looking at all those things which throw spanners in the

baby’s immune system programming – in utero and after birth, including

food, vaccines, mercury in teeth, and drugs.

The simple fact is that if we keep throwing monkey wrenches into a very

young immune system, we will guarantee that bad stuff will follow for the

rest of the baby's life.

Let’s look at this issue, working backwards. In 2010, A

medical article

was published which discussed the human neonatal system and how it was

similar to mice. So using mice, the author showed how, “... myosin

immunisation with complete Freund’s adjuvant and additional

lipopolysacchride (LPS is an endotoxin), induced

(autoimmune) disease. These findings clearly indicate that a potent

adjuvant effect can overcome the relative genetic resistance to

autoimmune disease. At the same time, we showed that blocking either

IL-1B or TNFa inhibits the development of disease even in highly

susceptible A/J mice”

A previous paragraph on the same page stated, “These experiments

convinced us that the administration of microbial products together with

self antigen greatly increases the probably that autoimmune disease

ensues”

Ah, but I hear you say, vaccines don’t include self-antigens. At least

two vaccines have certain peptides in the common, between the vaccines

and the human proteins in relation to surface antigen proteins:

Hepatitis B,

and Gardasil.

Bonnie Dunbar, Ph.D, a lone voice in the wilderness, has already stated

publicly that she considers the Hepatitis B vaccine " guilty " of

adverse reactions as a result of molecular mimicry between the relevant

proteins in the vaccine, and the immune system's response to them.

Other vaccines which have residual DNA from aborted fetal tissue (which

can also theoretically be treated by the body as “self” antigens, or

animal DNA from culture mediums which may cross-react, may also fulfil

the criteria of presenting “self-antigens” or “similar antigens” into the

recipient, subsequently resulting in autoimmunity. That apparently,

hasn't been considered at all.

Most vaccines have potent adjuvants as well as other foreign antigens,

and when you give several vaccines together ..... you more than fulfil

the criteria in

Rose 2010..

But to understand the significant of the 2010 Rose paper, we have to have

a look at HOW a baby’s immune system develops, and why.

We can do that by looking at

Chelvarajan 2004, where at that time, the author considered a baby’s

immune system to be “defective” precisely because a baby’s

immune system persistently and defiantly refuses to produce IL-1B and

TNFa – those same things mentioned in Rose 2010. Look at how many times

almost in disgust, Chelvarajan 2004 used the word “defect” or defective.

Let me repeat that:

Babies just won’t produce IL-1B and TNFa.

Which is why all the early vaccines, for Hib, which were not joined up

with a toxin and adjuvant to whack the immune system around the ears,

wouldn’t work.

Once they conjugated them onto a diphtheria or tetanus toxin, and other

adjuvants were added, to further push the red alert buttons in the baby,

the baby’s immune system had no option but to respond. The vaccine

manufacturers crowed at this marvel of technological success, wihch

corrected the baby’s “defective” immune system.

In 2004, Chelvarajan suggested that if vaccine pushers added various

immune system kickers into vaccines, this would solve the problem and fix

this horribly deviant system. All vaccines for Strep Pneumo, Hib

and Meningococcal diseases have potent adjuvants for this purpose,

because without them, the baby's immune system acts from the blue-print,

sits there and does nothing - just as it's supposed to do.

However, by

2007, Chelvarajan was seeing things differently, and stated in the

last paragraph, that whereas in the past, they had considered this a

“defect”, they now considered it “an important

developmental program” saying,

“This anti-inflammatory phenotype may be beneficial to the neonate at a

time when tissue growth and remodelling events are taking place at a

rapid pace... thus the inability of the neonate to respond to infection

with encapsulated bacteria may be the risk the organism takes for

successful development.”

Why " protect " tissue growth and remodelling? What is being

remodelled? From what - to what? If a baby's prime directive in

NON-INFLAMMATION, what could inflammation do to tissue growth and

remodelling that would be so bad?

Everything in a baby is growing so fast. The body, the gut, the immune

system, the brain – cognitive function. Your baby learns the fundamentals

of language at an astonishing speed and can be speaking single nouns

within 7 months of you doing nothing but talk to your baby.

If it is important for successful development of a baby to allow the RISK

of infection by NOT allowing two key parts of the primary infection

defence to " fire " , what’s the OTHER risk you might take, if you

force an immune system to do something it's not supoosed to

do....by causing repeated, chronic inflammation at the end of a needle?

Peripheral inflammation and vaccine adjuvants, can cause brain

inflammation; create allergies, autoimmunity - constant inflammation all

around the body - not just at the site of the injection... and.... cause

mitochondria to stop working properly.

The brain and the immune system, are the two key fundamentals of

successful, appropriate adaptation to the environment you live in.

Your baby’s immune system needs to recognise what to react to, and what

NOT to react to. Your baby’s brain needs to accurately, mentally respond

to everything around it.

And the key to this is a non-inflammatory

phenotype. If your baby learns this correctly, that process

greatly reduces the possibility of allergy, asthma and other

“inflammatory” disorders from developing in the first place. Even

Holt, in 2005, recognised that this was the key.

So here’s the next question?

If a baby’s default position is NOT to respond to

toxin-mediated bacterial diseases, what chance does a baby have to

survive potentially serious infections?

Part 2.

How a baby fights and develops the immune system.

http://www.beyondconformity.org.nz/_blog/%27s_Desk/post/How_a_baby_fights_infection_and_develops_the_immune_system/

- Tuesday, May 24, 2011

The main and unique intermediary step between a NON-INFLAMMATORY

phenotype, which is the default setting in pregnancy and for all baby

mammals - and a more individually competent educated immune system

better able to handle the world's dangers and challenges.... is breast

milk.

The prime directives programmed into breast milk in the first two years -

apart from " food " ... ARE:

1) To reinforce and control a

good balance of gut flora which help

block out disease causing pathogens, whether bacteria like

Hib, and

Pneumococcus or virusis like

Measles and

Rotavirus..

2) To maintain,

TEACH and regulate the immune system and to MAKE SURE that the prime

directive is REDUCTION OF ALL INFLAMMATORY processes,

and

ASTHMA or

ALLERGY producing markers. The reason for this is to learn to

distinguish " self " from an " outside " pathogenic

antigen.

3) To patrol the body for cancer and nuke anything multiplying

incorrectly, with a molecule called

HAMLET.

4) To optimise

bone density, and other hormone or enzyme pathways.

5) To supply

stem cells, so that in the event of something going seriously wrong,

those stem cells help the body to self-heal.

6) To

provide the baby with ready made immediate and long term T-cells for

the baby to use, which the baby immune system isn't " primed " to

make for itself.

7) To prevent the development of future

disease chronicity.

As

this

article says, " Human milk is the richest known source of

such immunomodulation and protection. "

So it’s no surprise that Il-1B and TNFa allong with other inflammatory

cytokines are not going to be produced in a baby whose core prime

directive is to PREVENT AND

REDUCE INFLAMMATION AT ALL COSTS. Babies are not supposed TO

RESPOND to any bacterial diseases, because the baby gets protection

from

toxin mediated diseases, by

neutralizing toxins with gangliosides from the mother’s breast

milk.

The reinforcement patterning from breast milk, is ... to continue

suppressing inflammation, preventing

coeliac disease, creating

good neuronal development, which determines a child’s future - not

just in terms of babies being brighter, but also in terms of children not

having

future behavioural problems and

adolescent depression. Breast milk has a key impact on the

pituitary gland, which in turn enhances the ability to

handle stress, long term.

NOTE:

Mothers who eat junk food, negate the effect of breast milk to

prevent allergy.

The

financial costs of NOT breastfeeding to society and individuals, both

short and long term, are

staggering.

At and after birth, neonates are in a period of transition where they are

exposed to a barrage of antigens in the mouth, and lungs. Injecting

antigens at this critical time, and claiming that they, “do nothing to

the immune system compared with the numbers of natural antigens....”

makes no sense whatsoever, and is certainly not supported by their own

medical literature.

In order to adjust to the world appropriately, not only is a

“non-inflammatory phenotype” critical, but breast milk is also essential

to protect the baby from toxin-mediated and other diseases while the

immune system develops appropriately.

But here’s another key to the story.

Up until recently, the brain and the immune system were considered to be

two separate entities. While Il-1B and TNFa are part of

the active immune system process in adults, what was NOT considered in

this equation, is that they are also key components in

remodelling neuronal pathways in the brain in babies, so if you

trigger them at a crucial time when neuronal connections are being built

faster than the speed of light, you are seriously compromising the

baby.

In September 2010, a medical article in Frontiers in Synaptic

Neuroscience made some staggering admissions on the state of knowledge in

this field:

" Although much progress has been made in the past 10 years in our

appreciation that immune molecules play critical roles in the healthy

brain, the large majority of immune molecules have not yet been

studied for their presence and function in the brain.

For the immune molecules that we know are important, almost

nothing is understood about their mechanisms of

action. "

Astonishingly, the authors look everywhere, including pregnant mothers

who - when they have even silent infections, release cytokines - to

provide and explanation for the immunological insults they see in

children with autism. The authors hypothesize what might have

triggered these immune molecules about which they know almost nothing,

and point the finger at everything, except the white elephant in

the room ... which are vaccines at this most critical time in

babyhood, and now, vaccines during pregnancy.

Here is the

UNMARKED article, and

here is a copy with my notations and markings.

Just maybe, that’s why a baby is programmed to DOWN-regulate the

inflammation part of the immune system, and not react to toxin-mediated

diseases the way an adult does.

So, the " risk " you take in upregulating

inflammation provokers, just might be that a baby's brain won't work as

smoothly. And it’s no fluke that breastmilk also has in it, unique

compounds which help to programme a baby’s brain correctly.

The

breastfed baby is still an extension of the mother in terms of immune

programming and brain development. The breast fed baby is dependant on

the mother’s breastmilk to switch on, and off specific genes – which will

optimise that baby's future development programming, immune protection

and appropriate recognition of “pathogen associated molecular

patterns” (PAMPS) .

Breastmilk programming also appears to confer a degree of protection

against

Type 2 diabetes, and

obesity later in life.

Breast milk also takes

food antigens, inhaled pollens etc... from a mothers lungs and

digestive tract, partners them with macrophages in the breastmilk, and

directly presents them to a baby as a message saying, “These are safe”.

Breast milk, correctly teaches recognition of self, and definition of

what is dangerous – the right way.

Summary: Breast milk's mission for at least two years, is

to prevent as much inflammation in the body, as possible,

to reduce the possibility of serious infection, allergies and

chronic disorders throughout life.

Question:

So what might happen when someone comes along with rafts of

needles from birth, and repeatedly, chronically, forces a baby’s body to

do something it’s NOT designed to do?

Part 3:

Can vaccines become cranial and immunological cluster bombs?

http://www.beyondconformity.org.nz/_blog/%27s_Desk/post/Can_vaccines_become_cranial_and_immunological_cluster_bombs/

- Wednesday, May 25, 2011

( Part 3 of 3 ) So what might happen when you repeatedly bombard a baby’s

immune system with vaccines?

It depends whether you believe

Dr Offit, the king pin at the Children’s Hospital at

Philadelphia and seemingly of late, the sole mouthpiece for vaccination

programs and the vaccine industry in the United States, who claims that

healthy infants can safely get up to 100,000 vaccines at once.

Yes, " Safely " !

I disagree with Dr. Offit. But then, I am only a country town hick

who never went to medical school, so what would I know?

But here’s why I disagree with him.

A baby develops “adaptive tolerance” by suppressing inflammatory

cytokines, including IL-1B and TNF-a, to make sure that T cells don’t

respond to everything naturally presented to the baby as “safe”.

IF a baby’s immune system is developing along a specific pathway which is

designed to SHUT DOWN INFLAMMATION, as an

“important developmental programme” - “beneficial to the neonate”

what might be the result of tossing vaccines into a baby immediately

after birth, and at regular intervals thereafter?

1) We know that in adults, influenza vaccines increase autoimmunity

antibodies

(

Isakov). Does this happen in infants and children? There

is no logical reason to believe that it doesn't, but we can't be sure

until such research is urgently undertaken - now that yearly influenza

vaccination is forced upon babies - and pregnant mothers.

2) We know that hepatitis B vaccines given to adolescents results in an

increase in alloreactive cellular responses

(

Roddy) and

http://www.ncbi.nlm.nih.gov/pubmed/20179666 , but that research

hasn’t extended to babies either. Neither have researchers looked

at what happens after regular booster shots. At such a crucial

non-inflammatory time, what would a neonatal immune system do with

increased allo-antibodies? The fact is no one has a clue!

3) We know that vaccination in adolescents can result in autoimmune

anti-NMDA encephalopathy

(

Hoffman), but unfortunately that research has not yet extended to

babies.

4) We know that vaccinating mice at the critical point of immune

development described by Chelvarajan, results in a skewing towards an

allergic Th2 immune system

(

Eurekalert and

Lee).

5) We also clearly know that the LONGER a parent delays

giving a DPT vaccine, the less the baby's chances of

developing

asthma.(

Mc)

A first vaccine is designed to PROVOKE inflammatory immune responses, and

booster shots are designed to enhance that inflammatory process, and to

keep it going for a long time.

The core of NEONATAL vaccine administration “theology” is

that the earlier we vaccinate babies, the better.

The alleged “objective” of regular booster vaccinations, is

that continuing to provoke the immature immune system of the baby, will

result in life-long memory T-cell immunity as a result of being

repeatedly vaccinated early in life.

The other untouchable tenet of NEONATAL vaccine “theology” is that

IPSO FACTO, all vaccines are safe, and do not affect, or

perturb the normal functioning of the immune system, and THAT anything

that happens after a vaccine is “coincidental”.

A recent study

(

Wherry) about " chronic " infection, has shown

that “pathogen persistence” in the body, results in the

body’s T-cells against that specific pathogen “giving up”.

This is called “T-cell exhaustion”. The author contrasts

the very specific immune system actions against acute infection: “After

infections that are cleared acutely, highly functional memory T-cells

develop....” with the across-the-board blunted action of the immune

system in chronic infections.

Acute infections ARE cleared from the body because they usually don’t

come through a needle with a whole array of foreign proteins and

adjuvants. The WAY the body clears an acute natural infection, is quite

different from the way a body is being forced to respond to repeated

injections of the same antigen.

What might happen IMMUNOLOGICALLY if you put in vaccines, a form of

applied " chronic " infections, into babies in the first few

weeks of life?

What are vaccines - if they aren’t a form of applied “chronic”

infections?

Might a different form of T-cell exhaustion happen later, to those

vaccinated babies?

The answer appears to be “yes”.

In a recent study

(

Posfay) adolescents were given a booster dose to check how they would

respond to the DPT vaccines they received at 6, 10 and 14 weeks of age.

Looking at tetanus antibodies, the authors found to their horror that

nearly half had no boost or increase in their tetanus antibodies. They

noted that a high proportion of teenagers who were given their primary

vaccinations on the early schedule simply had no response to boosters and

they conceded that, " early life immune immaturity may limit

the persistence of infant-induced immunity " .

Similar “refusal” to make booster T-cell dependant antibodies has

been documented in 14 year-old Alaskan children after Hepatitis B

boosters, as well as in 15 year-olds in Micronesia and Taiwan.

(

Lu)

In 2003,

Pihlgren showed that if mammals are vaccinated too early, memory IgG

responses to T-cell dependant antigens are suppressed. In mice it took 6

– 8 weeks for the immune system to mature enough to be able to start

making long term Ig G antibodies. Pihlgren stated that in humans,

the process is much longer, without specifying how long.

Both the mice and human studies, suggest that the core

theory that infant vaccination DOES NOT affect the immune system,

is incorrect.

That proof is staring us in the

face.Example. Paediatric EPI-PEN prescriptions are

at an all-time high.

Young and old adults, (who we are told haven’t yet co-operated with

the burgeoning adult vaccination programme and are seriously

undervaccinated), are not (yet) meaningfully represented in the huge

EPI-PEN prescription increase in young children.

Today's children, are the MOST vaccinated ever, in the

" during-the-crucial-neonatal-developmental " time

frame.

Is it some " fluke " that children today, have

the highest level of developmental disabilities in the history of

mankind?

Is this " real progress? "

In America

43% of children have chronic ill-health, and developmental disorders

affect

one in every six children.

This

study showed that 16.8% of children younger than 18 years of age

have lifelong conditions arising in early childhood as a result of

cognitive or physical impairment or a combination of the

two.

Everywhere in the developed world, parents are starting to notice the

huge numbers of children with serious chronic disorders and behavioural

issues. Older teachers readily see the difference between children

they taught years ago, and children entering school in 2011.

These figures are outrageous, but are explained away by the authors as

improved survival of children born preterm, or with birth defects or

genetic disorders - but I note - buried amongst a sack of other excuses

on page 1035 - was " new infant vaccines " . Just an

intsy ray of light there?

Also please note the preponderance of chronic conditions

" based on an emotional or behavioral

phenotype... " .

How about substituting that phrase, with my own theory, which is:

" A vaccine-enforced neonatal inflammatory phenotype triggering

inappropriate brain activity by activations of immune cytokines including

Il-1B and TNFa, which should be left well alone. "

It’s no good blaming the increased numbers on better diagnosis

as Boyle does, because that implies that these disabilities have

always been at these percentages, but that no-one noticed

before. Even the most naive parents can see through that

excuse.

It's also no good blaming older parents either, because in the days

before contraception, women continued to have children right up until

menopause.

Where are all the similarly blighted adults today, who were born to those

older mothers?

The medical profession argues that the solution is " better access to

medical care " when

it could be argued that it's the medical system throughout pregnancy

and after birth, that took the children to the very precipice on which

they now stand.

It’s my contention that vaccines, given to a baby within the

immunological window of vulnerability, described by Pihlgren, can force

some babies into an " inflammatory phenotype " resulting in the

possibility of:

1) an increase in allergy,

2) autoimmunity

3) the triggering of brain inflammation, with resultant chronic ill

health in many diverse ways...

and

4) an inability to respond to vaccine antigens previously injected during

this neonatal period.

We can't even restrict potential problems to neonatal time frames,

because

serious neurological disorders after DPT in adolescents have been

seen, where all of the current tests came back normal.

So clearly there's even more that isn't known about adolescent

neurology/immune system tie-ups as well.

For the reasons above, I believe that the current obsession to vaccinate

pregnant women, babies - earlier and earlier, and adolescents and adults

with as many vaccines as possible - will result in:

.... the most immunologically damaged population the world has ever

seen.

I believe that the writing is being written on the wall,

for those with the eyes to see the finger moving.

No doubt these same people who didn't realise that the brain and

the immune system were connected until about a year ago, will all

have their own plausible theories to protect vaccine programmes, and

explain away neonatal immune system problems rarely seen in children

decades ago. Immune systems, which, by their own admission, they

know virtually nothing about.

It's no longer acceptable to tell a parent, " The vaccine

didn't do this. We don't know what did, but WE KNOW a vaccine

didn't do this. " because they " know " nothing of

the sort. They may believe it but certainly no more!

It's also not acceptable to bully parents into giving their babies any

vaccines at all, when immunologists haven't the foggiest what those

vaccines do in a baby's body, let alone a baby's developing

brain.

It's time the medical profession took a long hard realistic look at the

huge numbers of chronically sick children they treat, and ask the same

questions that parents and those of us without medical training, have

been asking for a very long time.

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

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