2002 Article / Olfactory NeuroEpithelium / Surgery?

August 9, 2010

I want to share this study I came across from Dr. Leopold in Nebraska, it caught

my attention.

Just a quick recap - I inhaled through my nose some concentrated spot cleaner

and caused, in my opinion, permanent damage to my olfactory neuroepithelium

resulting in excitotoxicity resembling what some may call Multiple Chemical

Sensitivity. I take an NMDA antagonist to get through the day. I am now

hypersensitive to one unknown particle, whether it's a volatile organic

compound, mycotoxin, solvent, I'm not sure, but it significantly impacts my

life. In its presence I have severe fatigue, neurologic impairment, and " brain

fog. " At its worst, I couldn't swallow correctly. I do however believe it is a

mycotoxin of some sort. Like many on here, I have left everything behind

(porous items, homes, cars) and I just feel it is something of that nature.

Please take a look at this if you feel your condition results from some particle

landing on your nasal olfactory epithelium resulting in hypersensitivity:

His article is related to olfaction, not necessarily some unknown chemical

landing on your olfactory epithelium resulting in some irrational response,

excitotoxicity, NMDA, etc..

But, I have never seen any doctor recommend the following... 1. using

lidocaine/cocaine to block the olfactory neuroepithelium to determine if that in

fact is the source of the problem. 2. Removing the neurons via surgery (I'm

really dumbing this down).

Has anyone ever heard of this before? Surgery to remove the olfactory

epithelium would truly scare me. But has anyone considered it or heard of

others who have? I mean, if you confirm it with blocks beforehand, it seems

reasonable that it would work.

Thanks for any input. I understand not everyone feels they have CFS/SBS/MCS

related to olfactory damage, and this perhaps is a better fit for the MCS forum,

but I wanted to get your thoughts if any.

Best Regards,

Tom

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