Guest guest Posted August 18, 2010 Report Share Posted August 18, 2010 I think this subject needs to be put into sometype on context as to just how much of a role it plays with mycotoxins, possable other toxins involved in WDB exposures. from my understanding just from what I gathered through research, includeing studies that may or may not be faulty, but more so based on anatomy and other articfacts that I read that I felt were pretty well substanuated facts. in order for the HLA to play a role here, first you have to realize that it only comes into play by antigen presentation or things that are presented as antigens, so far to me, that means allergens and I do recall that some type of mycotoxin from I believe stachy and maybe that other molds produce is presented as a antigen through this route. not everything that can be involved in a WDB is presented this way. from what I gathered bacteria is not, I dont know about other toxins in the WDB. I have also read that there are other ways,cell functions involved in detoxing and other routes of detox involved. I have read things that led me to believe that overall, HLA may only have about a 20 percent role here, than fracting that down to exactly what might be involved in a WDB exposure, maybe by half or more, it leaves me wondering just how much role it actually plays here. than you have the several different bad genes possable, I only have one. now I dont really care who says what on the subject of dose, I know it cant be measured, but the overall toxicity of a WDB does mater. and of corse our body health wize and even right down to our nose and breathing matters, snot matters,ect. there really is not possable way to deturmine how each and everyone of us would suffer to the exact same exposure. now saying there is 25 persent of people that have these bad genes, one or more, and I take it that the more you have the more this might be a factor, theres still the factor of what is actually be presented in every WDB exposure and how or what may be a factor of the HLA genotypes. one of those factors would depend on your bodily functions , related to dose and your ability to clear mycotoxins and other thing from your system . dose does matter because if you get a dose that your bodily functions cant keep up with your in trouble and at this point what role would the dreaded genotypes even play, I doubt very much. now I see where a toxin is a toxin and if it's presented this route these HLA genitics role a role. but thats just really of small piece of what happens here. I think some put to much into that one factor. however, I can see were it may become more of a issue after exposure with re-exposures to even small amounts on mold and its byproducts and the fact that we may not be detoxing like we should. but at the same time our we are also dealing with other toxins in our invoronment that add to our toxic load that are not presented this way and I believe our exposures afterwards are very few inbetween if much at all mycotoxin related, or related to the type of mycotoxins that has been reported as being presented as a antigen, because I dont know that that means all mycotoxins are presented that way. haveing said that I do know that mycotoxins can be involved in some things, even in the air/dust we breath in when outside. but how much of that actually gets into our system,and what is caught and disposed of ,like by snot for example, all still plays a role. and ofcorse even this function can be altered by a damageing exposure in a WDB. SO, I guess I just answered my own question, theres just to many factors involved here to really put the blame on any one thing. and it doesn't even seem like it's possable to really give a persentage on how much of a role this really plays here. so knowing that 25 percent of the population may have these genitics really in no way possable can deturmine just how much these genitics played a role in each case of WDB exposure or the role afterwards. just my thoughts, I am more than open to listening to other points of view. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.