toxins may augment IgE responce

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Exposure to the Immunosuppresant, Perfluorooctanoic Acid, Enhances the Murine

IgE and Airway Hyperreactivity Response to Ovalbumin

In a murine model, PFOA was demonstrated to be immunotoxic following dermal

exposure, with an enhancement of the hypersensitivity response to OVA,

suggesting that PFOA exposure may augment the IgE response to environmental

allergens.

The persistence of PFOA in the environment in combination with these findings

suggest that exposure to PFOA, although not allergenic itself, may enhance an

individual's response to commonly encountered environmental allergens.

http://toxsci.oxfordjournals.org/content/97/2/375.abstract