Guest guest Posted April 25, 2010 Report Share Posted April 25, 2010 I used Melatonin for jet lag once. It did nothing but keep me awake for days. Like some medications, it had the reverse effect for me again. My CMT wasn't affected, I just didn't sleep and walked and shopped alot since I was so awake, lol Info at http://en.wikipedia.org/wiki/Melatonin#Treatment_of_circadian_rhythm_disorders It can act as a mild hypnotic, which can cause muscle relaxation. Also see http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-melatonin.html Benzodiazepine tapering A small amount of research has examined the use of melatonin to assist with tapering or cessation of benzodiazepines such as diazepam (Valium®) or lorazepam (Ativan®). Although preliminary results are promising, further study is necessary before a firm conclusion can be reached. Side Effects and Warnings Based on available studies and clinical use, melatonin is generally regarded as safe in recommended doses for short-term use. Available trials report that overall adverse effects are not significantly more common with melatonin than placebo. However, case reports raise concerns about risks of blood clotting abnormalities (particularly in patients taking warfarin), increased risk of seizure, and disorientation with overdose. Commonly reported adverse effects include fatigue, dizziness, headache, irritability, and sleepiness, although these effects may occur due to jet-lag and not to melatonin itself. Fatigue may particularly occur with morning use or high doses, and irregular sleep-wake cycles may occur. Disorientation, confusion, sleepwalking, vivid dreams and nightmares have also been noted, with effects often resolving after cessation of melatonin. Due to risk of daytime sleepiness, those driving or operating heavy machinery should take caution. Headache has been reported. Ataxia (difficulties with walking and balance) may occur following overdose. Quote Link to comment Share on other sites More sharing options...
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