Guest guest Posted December 31, 2010 Report Share Posted December 31, 2010 As 2010 ends, we are encouraged by the amount of extraordinary research that has been completed for Charcot Marie Tooth neuromuscular disease this year. We saw the refreshingly positive resurrection of NT-3 as a nerve growth factor, followed by initial reports on the use of Ascorbic Acid (both for CMT 1A), the highly successful work of high thoroughput screening of potential theraputic targets for CMT treatment, the possibility of antibiotic use for CMT 2E, the enlightened work of the private, venture capital funded Phase II human trials project from the French biotech Pharnext, and the latest research from Italy on the walking bioenergetics, neuromechanics and physical activity in persons with Charcot-Marie-Tooth syndrome. CMT research in total has made stellar strides since the first CMT subtype (CMT 1A) was defined in 1991. We've come a long way in 20 years! World genetic research and two additional Italian studies, one looking at the effect of recovery time after fatigue and another looking at the correlation between levels of daily living activity and neuromuscular function fire us with hope for the New Year 2011 and the possibility of treatment and total arrestment of CMT once and for all. Quote Link to comment Share on other sites More sharing options...
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