Guest guest Posted November 18, 2010 Report Share Posted November 18, 2010 The more I try to learn about my disability, the more educated I become. As a CMT1 (and probably a 1A), I see a lot of myself in the article posted. Dick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 29, 2010 Report Share Posted December 29, 2010 Neuromuscular Disorders Volume 21, Issue 1, Pages 52-57 (January 2011) Charcot-Marie-Tooth 1A patients with low level of impairment have a higher energy cost of walking than healthy individuals Federica Menottia, Francesco Felicia, Antonello Damianib, Fortunato Mangiolab, o Vannicellib, Macalusoa Abstract The study aimed at quantifying the walking energy cost of a group of Charcot-Marie-Tooth 1A patients (CMT1A), with low severity of walking impairment, in comparison with healthy individuals. Oxygen uptake was measured in 8 patients (age-range 20–48years; Barthel >90; Tinetti >20) and 8 healthy individuals, matched for age and gender, when walking on a circuit for 5-min at their self-selected speeds ( " slow " , " comfortable " and " fast " ). Both comfortable and fast speeds were lower in patients than in the control group (0.92±0.16 vs 1.16±0.22 and 1.27±0.27 vs 1.61±0.22ms & #8722;1, respectively; P<0.05), whereas walking energy cost per unit of distance was higher in patients than in the control group (P<0.05) at both " comfortable " (2.27±0.35 vs 1.92±0.21Jkg & #8722;1m & #8722;1) and " fast " speed (3.05±0.35 vs 2.37±0.42Jkg & #8722;1m & #8722;1). CMT1A patients, therefore, choose to walk slower but with higher metabolic cost compared to healthy individuals, despite no clinically evident walking impairment, which is likely due to altered walking patterns. Quote Link to comment Share on other sites More sharing options...
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