Guest guest Posted June 1, 2006 Report Share Posted June 1, 2006 I'll plaster this one on the fridge. My husband always wants me to sit around are rest. I can't do that. Thanks <Matsumura_Clan@...> wrote: J Rheumatol. 2005 Jun;32(6):1031-9. Can progressive resistance training reverse cachexia in patients with rheumatoid arthritis? Results of a pilot study. Marcora SM, Lemmey AB, Maddison PJ. School of Sport, Health and Exercise Sciences, University of Wales-Bangor, and Department of Rheumatology, Gwynedd Hospital, Bangor, Wales, UK. OBJECTIVE:. A Phase II trial was performed as a preliminary test of the efficacy and safety of progressive resistance training (PRT) as adjunct treatment for rheumatoid cachexia. METHODS: Ten mildly disabled patients with well-controlled rheumatoid arthritis (RA) trained, on average, 2.5 times per week for 12 weeks. Ten age and sex matched RA patients with similar disease characteristics were non-randomly assigned to a control group. Body composition, physical function, and disease activity were assessed pre and post intervention period. RESULTS: Between group comparisons at followup by ANCOVA using baseline scores as covariate showed significant increases in fat-free mass (+1253 g, p = 0.004), total body protein (+1063 g, p = 0.044), and arm (+280 g, p = 0.005) and leg (+839 g, p = 0.001) lean mass (a proxy measure of total body skeletal muscle mass) in response to PRT with no exacerbation of disease activity. There was also a trend for loss of fat mass in the trunk (-752 g, p = 0.084) and a significant reduction in percent body fat (-1.1%, p = 0.047). Changes in body composition were associated with improvements in various measures of physical function. CONCLUSION: Intense PRT with adequate volume seems to be an effective and safe intervention for stimulating muscle growth in patients with RA. Pending confirmation of these results in a larger randomized controlled trial that includes patients with more active and severe disease, a similar PRT program should be included in the management of RA as adjunct treatment for cachexia. PMID: 15940763 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\ ct & list_uids=15940763 Not an MD I'll tell you where to go! Mayo Clinic in Rochester http://www.mayoclinic.org/rochester s Hopkins Medicine http://www.hopkinsmedicine.org Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 1, 2006 Report Share Posted June 1, 2006 Many years ago, I also though I couldn't exercise or I would damage my joints. I'm so glad current research has informed me otherwise. Of course we still have to use common sense. I've learned to recognize the pain I am able to work through and the pain that says STOP!!! a On Jun 1, 2006, at 7:50 AM, C. Y. wrote: > I'll plaster this one on the fridge. My husband always wants me to > sit around are rest. I can't do that. > > Thanks > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 2, 2006 Report Share Posted June 2, 2006 To your health, ! Not an MD I'll tell you where to go! Mayo Clinic in Rochester http://www.mayoclinic.org/rochester s Hopkins Medicine http://www.hopkinsmedicine.org Re: [ ] RESEARCH - resistance training ((())) > I'll plaster this one on the fridge. My husband always wants me to sit > around are rest. I can't do that. > > Thanks > > > <Matsumura_Clan@...> wrote: > J Rheumatol. 2005 Jun;32(6):1031-9. > > > Can progressive resistance training reverse cachexia in patients with > rheumatoid arthritis? Results of a pilot study. > > > Marcora SM, Lemmey AB, Maddison PJ. > > School of Sport, Health and Exercise Sciences, University of Wales-Bangor, > and Department of Rheumatology, Gwynedd Hospital, Bangor, Wales, UK. > > OBJECTIVE:. A Phase II trial was performed as a preliminary test of the > efficacy and safety of progressive resistance training (PRT) as adjunct > treatment for rheumatoid cachexia. METHODS: Ten mildly disabled patients > with well-controlled rheumatoid arthritis (RA) trained, on average, 2.5 > times per week for 12 weeks. Ten age and sex matched RA patients with > similar disease characteristics were non-randomly assigned to a control > group. Body composition, physical function, and disease activity were > assessed pre and post intervention period. RESULTS: Between group > comparisons at followup by ANCOVA using baseline scores as covariate > showed > significant increases in fat-free mass (+1253 g, p = 0.004), total body > protein (+1063 g, p = 0.044), and arm (+280 g, p = 0.005) and leg (+839 g, > p > = 0.001) lean mass (a proxy measure of total body skeletal muscle mass) in > response to PRT with no exacerbation of disease activity. There was also a > trend for loss of fat mass in the trunk (-752 g, p = 0.084) and a > significant reduction in percent body fat (-1.1%, p = 0.047). Changes in > body composition were associated with improvements in various measures of > physical function. > > CONCLUSION: Intense PRT with adequate volume seems to be an effective and > safe intervention for stimulating muscle growth in patients with RA. > Pending > confirmation of these results in a larger randomized controlled trial that > includes patients with more active and severe disease, a similar PRT > program > should be included in the management of RA as adjunct treatment for > cachexia. > PMID: 15940763 > > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\ ct & list_uids=15940763 > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 2, 2006 Report Share Posted June 2, 2006 Thank you. It's good to know I can always count on one of our groupies to understand. It helps. <Matsumura_Clan@...> wrote: To your health, ! Not an MD I'll tell you where to go! Mayo Clinic in Rochester http://www.mayoclinic.org/rochester s Hopkins Medicine http://www.hopkinsmedicine.org Re: [ ] RESEARCH - resistance training ((())) > I'll plaster this one on the fridge. My husband always wants me to sit > around are rest. I can't do that. > > Thanks > > > wrote: > J Rheumatol. 2005 Jun;32(6):1031-9. > > > Can progressive resistance training reverse cachexia in patients with > rheumatoid arthritis? Results of a pilot study. > > > Marcora SM, Lemmey AB, Maddison PJ. > > School of Sport, Health and Exercise Sciences, University of Wales-Bangor, > and Department of Rheumatology, Gwynedd Hospital, Bangor, Wales, UK. > > OBJECTIVE:. A Phase II trial was performed as a preliminary test of the > efficacy and safety of progressive resistance training (PRT) as adjunct > treatment for rheumatoid cachexia. METHODS: Ten mildly disabled patients > with well-controlled rheumatoid arthritis (RA) trained, on average, 2.5 > times per week for 12 weeks. Ten age and sex matched RA patients with > similar disease characteristics were non-randomly assigned to a control > group. Body composition, physical function, and disease activity were > assessed pre and post intervention period. RESULTS: Between group > comparisons at followup by ANCOVA using baseline scores as covariate > showed > significant increases in fat-free mass (+1253 g, p = 0.004), total body > protein (+1063 g, p = 0.044), and arm (+280 g, p = 0.005) and leg (+839 g, > p > = 0.001) lean mass (a proxy measure of total body skeletal muscle mass) in > response to PRT with no exacerbation of disease activity. There was also a > trend for loss of fat mass in the trunk (-752 g, p = 0.084) and a > significant reduction in percent body fat (-1.1%, p = 0.047). Changes in > body composition were associated with improvements in various measures of > physical function. > > CONCLUSION: Intense PRT with adequate volume seems to be an effective and > safe intervention for stimulating muscle growth in patients with RA. > Pending > confirmation of these results in a larger randomized controlled trial that > includes patients with more active and severe disease, a similar PRT > program > should be included in the management of RA as adjunct treatment for > cachexia. > PMID: 15940763 > > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\ ct & list_uids=15940763 > > > > Quote Link to comment Share on other sites More sharing options...
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