Re: Ibuprofen and heart attacks

[Guest guest]

,

This is something you will have to discuss with your rheumatologist.

In this study a meta-analysis was done on 138 randomized trials involving

NSAIDs (both traditional and COX-2) conducted from 1966 through 2005 and a

total of 145, 373 subjects.

The authors conclude that, compared to placebo, there is increased

cardiovascular risk with COX-2s (mostly MI) and with high-dose ibuprofen

(800 mg 3 times per day) and diclofenac (75 mg two times per day) but not

with naproxen (500 mg 2 times per day).

For the actual numbers, here is the study journal article:

BMJ

2006;332:1302-1308

" Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal

anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis

of randomised trials " :

http://bmj.bmjjournals.com/cgi/content/full/332/7553/1302

Reuters Health article on the study:

http://www.medscape.com/viewarticle/533682

Given that individuals will have different baseline risk factors and that

there is also a risk in not reducing the inflammatory burden of RA, your

physician is the best one to decide which NSAID, if any, and at what dose is

safe for you.

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

[ ] Ibuprofen and heart attacks

> , I heard on the news last night that Ibuprofen is dangerous and

> causes heart attacks...News was limited...just the schock value to get

> your attention...Not much info other than what I just mentioned and

> the doctor who discovered and reported the danger suggested aspirin

> use instead...Have you heard about this and do you have any info....Mu

> rheumy has me on Ibuprofen for pain and inflammation....Didn't take it

> today and won't until I get verified info as to its

> safety......Thanks, Hugs

[Guest guest]

, Thank you for the info on Ibuprofen....I will talk to my rheumy about

this....I just don't know what is safe anymore....Hugs

<Matsumura_Clan@...> wrote: ,

This is something you will have to discuss with your rheumatologist.

In this study a meta-analysis was done on 138 randomized trials involving

NSAIDs (both traditional and COX-2) conducted from 1966 through 2005 and a

total of 145, 373 subjects.

The authors conclude that, compared to placebo, there is increased

cardiovascular risk with COX-2s (mostly MI) and with high-dose ibuprofen

(800 mg 3 times per day) and diclofenac (75 mg two times per day) but not

with naproxen (500 mg 2 times per day).

For the actual numbers, here is the study journal article:

BMJ

2006;332:1302-1308

" Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal

anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis

of randomised trials " :

http://bmj.bmjjournals.com/cgi/content/full/332/7553/1302

Reuters Health article on the study:

http://www.medscape.com/viewarticle/533682

Given that individuals will have different baseline risk factors and that

there is also a risk in not reducing the inflammatory burden of RA, your

physician is the best one to decide which NSAID, if any, and at what dose is

safe for you.

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

[ ] Ibuprofen and heart attacks

> , I heard on the news last night that Ibuprofen is dangerous and

> causes heart attacks...News was limited...just the schock value to get

> your attention...Not much info other than what I just mentioned and

> the doctor who discovered and reported the danger suggested aspirin

> use instead...Have you heard about this and do you have any info....Mu

> rheumy has me on Ibuprofen for pain and inflammation....Didn't take it

> today and won't until I get verified info as to its

> safety......Thanks, Hugs