Fragile X and DS share signalling pathway- MR

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"The scientists revealed that the Down syndrome critical region 1 protein (DSCR1) interacts with Fragile X mental retardation protein (FMRP) to regulate dendritic spine formation and local protein synthesis. By using specific antibodies that bind to the proteins as well as fluorescent labeling techniques they showed that DSCR1 specifically interacts with the phosphorylated form of FMRP. The overlapping molecular pathways of intellectual disability in both genetic disorders suggest that a common therapeutic approach might be feasible for both syndromes."<http://medicalxpress.com/news/2012-08-fragile-syndromes-pathway-intellectual-disability.html>Liora Pearlman , ModeratorMom Please consider calling me at 5130 3931 or texting 139 1030 6022 if it is time sensitive. Facebook: https://www.facebook.com/liorap2