CASE REPORTS - New onset or exacerbation of psoriatic skin lesions in patients receiving anti-TNF therapies

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Ann Rheum Dis. 2006 Mar;65(3):405-7. Epub 2005 Sep 8.

New onset or exacerbation of psoriatic skin lesions in patients with

definite rheumatoid arthritis receiving tumour necrosis factor alpha

antagonists.

Kary S, Worm M, Audring H, Huscher D, Renelt M, Sorensen H, Stander E, Maass

U, Lee H, Sterry W, Burmester GR.

Department of Rheumatology and Clinical Immunology, Charite-University

Medicine Berlin, Schumannstr 20-21, 10117 Berlin, Germany.

BACKGROUND: Blockage of tumour necrosis factor alpha (TNFalpha) is highly

effective in rheumatic diseases, especially in rheumatoid arthritis (RA),

ankylosing spondylitis, and psoriatic arthritis. Furthermore, TNFalpha

antagonists have also been shown to significantly reduce psoriatic skin

lesions. CASE REPORTS: A series of nine patients with RA who were treated

with different types of TNFalpha antagonists and who unexpectedly developed

either a new onset or an exacerbation of psoriatic skin lesions are

reported.

PMID: 16150791

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=16150791

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