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Methotrexate Question

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When I was on oral mtx, it made me sick to my stomach. The injections

don't bother my stomach.

Hopefully you will adjust to the mtx, but if you continue to have

stomach aches and diarrhea, please

tell your doctor. He may switch you to the injections, which are

more effective. I get fatigue too. If you take it

at night before bed, you may sleep through the side effects. I'm

usually tired the next day.

a

On Nov 14, 2005, at 9:44 PM, morg332000 wrote:

>

> Hi all,

>

> Just started drug yesterday. 2.5 x 4 once a week

>

> Stomach cramps diareeha 5 1/2 hrs later.

>

> Not too bad, just a couple of incidents. Nothing today.

> Real tired yesterday and today.

> This seem to be the case with most of you?

>

> Also on hydroxychloroquine 200 mg twice a day

> and Folic acid.

>

> Thanks

> M

>

>

>

>

>

>

>

>

>

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Hi M, Welcome to the group. I had the same problem when I first started on

10mg and after about 4 or 5 doses it ceased as my body got used to it. As long

as it is not any more than a trip or two its probably not a problem and you may

want to give it a few weeks to see if it resolves on its own. Any longer or

more severe than that and you probaply need to mention it to your Dr.. Also

fatigue for a couple of days is a very common side effect and to be expected.

It took about 4 weeks for me to notice a difference in joint pain and

stiffness. Hope it works for you.

morg332000 <lubrazzi@...> wrote:

Hi all,

Just started drug yesterday. 2.5 x 4 once a week

Stomach cramps diareeha 5 1/2 hrs later.

Not too bad, just a couple of incidents. Nothing today.

Real tired yesterday and today.

This seem to be the case with most of you?

Also on hydroxychloroquine 200 mg twice a day

and Folic acid.

Thanks

M

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I was having a problem like that with my dose- 2.5 X 8. My doc just split it

up- I now do 2.5 X 4 on Thurs and then again on Sunday. Its a lot easier on

my stomach. Give it a few does and if it still bothers your tummy- ask your

doc if you can split it to two does.

Jill

On 11/14/05, morg332000 <lubrazzi@...> wrote:

>

>

> Hi all,

>

> Just started drug yesterday. 2.5 x 4 once a week

>

> Stomach cramps diareeha 5 1/2 hrs later.

>

> Not too bad, just a couple of incidents. Nothing today.

> Real tired yesterday and today.

> This seem to be the case with most of you?

>

> Also on hydroxychloroquine 200 mg twice a day

> and Folic acid.

>

> Thanks

> M

>

>

>

>

>

>

>

>

>

Link to comment
Share on other sites

I meant to type doses- but I cant type too well due to a major flare- wrist

and hand is really swollen! Sorry.

Jill

On 11/19/05, Jill Watkins <jill.watkins@...> wrote:

>

> I was having a problem like that with my dose- 2.5 X 8. My doc just split

> it up- I now do 2.5 X 4 on Thurs and then again on Sunday. Its a lot

> easier on my stomach. Give it a few does and if it still bothers your tummy-

> ask your doc if you can split it to two does.

> Jill

>

> On 11/14/05, morg332000 <lubrazzi@...> wrote:

> >

> >

> > Hi all,

> >

> > Just started drug yesterday. 2.5 x 4 once a week

> >

> > Stomach cramps diareeha 5 1/2 hrs later.

> >

> > Not too bad, just a couple of incidents. Nothing today.

> > Real tired yesterday and today.

> > This seem to be the case with most of you?

> >

> > Also on hydroxychloroquine 200 mg twice a day

> > and Folic acid.

> >

> > Thanks

> > M

> >

> >

> >

> >

> >

> >

> >

> >

> >

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  • 2 months later...

Hello,

I was diagnosed with R.A. in 2002 and I have been giving myself

Methotrexate Injections since 2003. Just recently my liver functions

have been slightly elevated. My doctor says it is a normal reaction and

my levels are not critical in anyway.

So my 1st question is: Has anyone that has taken Methotrexate had any

liver problems and if yes what was the course of action taken

2nd Question: If you have had liver problems did you consider or try a

natual liver flush??

Thank You So Much!!

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  • 2 years later...

When I was on MTX, it only lasted about 4 - 5 days. Whether this was a true

biological effect or a placebo effect, after that time period I was more achy

until I had to take my next dose.

Shandi

maggiemac52 <maggiemac52@...> wrote:

I take my methotrexate on Sundays. It seems to me that on Saturday

(and

sometimes on Friday), I wake up achy. Is it my imagination or does

methotrexate " wear off " by the end of the week? I also am on Remicade

infusions every 8 weeks. I had to stop taking my anti-inflammatories

last year because of stomach problems - I just started noticing this

after I stopped taking Daypro.

---------------------------------

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