Guest guest Posted September 18, 2006 Report Share Posted September 18, 2006 In the middle of May, my 78-year-old Mother added Enbrel to her regimen of MTX and Medrol to treat her RA. Until about 3 weeks ago, it was working wonderfully. She was mercifully free of pain. About a month ago, she was able to begin a water exercise program and had, most importantly, been able to lower her dose of Medrol to 2 mg/day. She has been on Medrol for a year at varying doses. Sadly, within the past 3 weeks, she has begun to have joint pain - two days of intense joint pain, then reduction of pain for a couple of days, and then another 2-3- day flair. I wonder if perhaps Enbrel is losing its effectiveness for her. Another oddity, she had not had any injection site reactions until two weeks ago, and has now had them with both of her last two injections. Does this scenario sound familiar to anyone else, and, if so, what's the next step? Quote Link to comment Share on other sites More sharing options...
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