Re: Question about Sjogren's

[Guest guest]

Hi Kim. There does appear to be a correlation:

Joint Bone Spine. 2002 Jun;69(4):383-7.

Related Articles, Links

Is the relationship between spondyloarthropathy and Sjogren's

syndrome in women coincidental? A study of 13 cases.

o di Fazano C, Grilo RM, Vergne P, Coyral D, Inaoui R, Bonnet C,

Bertin P, Treves R.

Department of Rheumatology and Therapeutic, University Hospital

Dupuytren, Limoges, France.

OBJECTIVE: To determine the prevalence of Sjogren's syndrome (SS) in

women with spondyloarthropathy (SpA). METHODS: Forty-one women with

SpA manifesting as inflammatory back pain and/or peripheral arthritis

were diagnosed as having ankylosing spondylitis, undifferentiated

spondyloarthropathy, psoriatic arthritis, or enteropathic arthropathy

based on accepted criteria. A validated questionnaire was used to

look for sicca symptoms in the SpA group and in 102 controls with

degenerative rheumatic diseases. Women with SpA and sicca symptoms

and/or positive antinuclear antibodies (ANA) were investigated for SS

by minor salivary gland biopsy. In the SpA group, the following tests

were done: HLA B27; HLA DR, DQ; ENA; and serology for CMV, EBV, HIV,

hepatitis B, and hepatitis C. RESULTS: Thirteen women (31.7%) met

European criteria for SS, compared to three (2.9%) of the controls.

Of the 41 women with SpA, 16 (39%) were ANA-positive. ANA were

detected in eight of the 16 (50%) patients with SS. HLA B27 was

present in 11 of the 13 (84.6%) SS patients. HLA DR 04.04 and DQ

03.03 seemed more common in SS patients, but the difference was not

statistically significant. CONCLUSION: SS was far more common in the

women with SpA (31.7%) than in the controls (2.9%), suggesting that

the SpA-SS association may not be coincidental.

PMID: 12184435 [PubMed - indexed for MEDLINE]

On Mar 9, 2006, at 4:56 PM, ksamedifference wrote:

> Is there any correlation of Sjogren's with spinal arthritis? KIm

>

a

[Guest guest]

Thanks a! You always get the good stuff! Take

care. Kim

--- a Papola <a54@...> wrote:

> Hi Kim. There does appear to be a correlation:

>

>

> Joint Bone Spine. 2002 Jun;69(4):383-7.

> Related Articles, Links

>

> Is the relationship between spondyloarthropathy and

> Sjogren's

> syndrome in women coincidental? A study of 13 cases.

>

> o di Fazano C, Grilo RM, Vergne P, Coyral D,

> Inaoui R, Bonnet C,

> Bertin P, Treves R.

>

> Department of Rheumatology and Therapeutic,

> University Hospital

> Dupuytren, Limoges, France.

>

> OBJECTIVE: To determine the prevalence of Sjogren's

> syndrome (SS) in

> women with spondyloarthropathy (SpA). METHODS:

> Forty-one women with

> SpA manifesting as inflammatory back pain and/or

> peripheral arthritis

> were diagnosed as having ankylosing spondylitis,

> undifferentiated

> spondyloarthropathy, psoriatic arthritis, or

> enteropathic arthropathy

> based on accepted criteria. A validated

> questionnaire was used to

> look for sicca symptoms in the SpA group and in 102

> controls with

> degenerative rheumatic diseases. Women with SpA and

> sicca symptoms

> and/or positive antinuclear antibodies (ANA) were

> investigated for SS

> by minor salivary gland biopsy. In the SpA group,

> the following tests

> were done: HLA B27; HLA DR, DQ; ENA; and serology

> for CMV, EBV, HIV,

> hepatitis B, and hepatitis C. RESULTS: Thirteen

> women (31.7%) met

> European criteria for SS, compared to three (2.9%)

> of the controls.

> Of the 41 women with SpA, 16 (39%) were

> ANA-positive. ANA were

> detected in eight of the 16 (50%) patients with SS.

> HLA B27 was

> present in 11 of the 13 (84.6%) SS patients. HLA DR

> 04.04 and DQ

> 03.03 seemed more common in SS patients, but the

> difference was not

> statistically significant. CONCLUSION: SS was far

> more common in the

> women with SpA (31.7%) than in the controls (2.9%),

> suggesting that

> the SpA-SS association may not be coincidental.

>

> PMID: 12184435 [PubMed - indexed for MEDLINE]

>

>

>

> On Mar 9, 2006, at 4:56 PM, ksamedifference wrote:

>

> > Is there any correlation of Sjogren's with spinal

> arthritis? KIm

> >

>

>

>

> a

>

>

>

>

>

>

> [Non-text portions of this message have been

> removed]

>

>

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