RESEARCH - Vocal fold deposits in autoimmune disease - an unusual cause of hoarseness

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Clin Otolaryngol Allied Sci. 2003 Oct;28(5):446-50.

Vocal fold deposits in autoimmune disease--an unusual cause of hoarseness.

Ylitalo R, Heimburger M, Lindestad PA.

Department of Logopedics and Phoniatrics, Karolinska Institute, Huddinge

University Hospital, Stockholm, Sweden. riitta.h.ylitalo@...

The objective of this study was to evaluate the symptoms and clinical

characteristics in patients with autoimmune vocal fold deposits. Fourteen

patients underwent videolaryngostroboscopic examination and voice recording.

Eleven of the 14 patients underwent rheumatological examination. In all

cases, endoscopic examination showed transverse white-yellow band lesions in

the middle of the membranous portion of the vocal folds. In most cases, the

lesions were bilateral but not exactly opposing each other. The most common

voice characteristics were instability and intermittent aphonia.

Inflammatory disease was present in 10 patients; five of these had

rheumatoid arthritis (RA). No immunological signs common for all patients

could be found. The histological examination was consistent with rheumatoid

nodules. Vocal fold deposits, occurring most often in patients with RA, is

an uncommon cause of hoarseness. Because the patients may have hoarseness as

their primary symptom, it is important for otolaryngologists to be familiar

with this disorder.

PMID: 12969349

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=1\

2969349

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