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Re: Celebrex & Vioxx

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I take Celebrex for my RA when I need it. It was the one RX that helped me.

I don't believe it contributes to intestinal bleeding, but there are the

heart issues that were in the news over the last year that led to the

removal of Vioxx and Bextra.

My cardiologist recommended (and my rheumatologist agreed) that I should

take a low dose aspirin while on Celebrex to offset the cardiac problems.

For the record, I take Plaquenil. I took the Celebrex for months until the

Plaquenil kicked in - it is a very slow acting drug and can take months for

it to help. At that time, I eliminated the Celebrex. Unfortunately, due to

a neuropathy issue, I was taken off the Plaquenil for about 2 months at the

beginning of this year. When the arthritic problems came back, I went back

on Celebrex. I'm not back on Plaquenil and now, I'm trying to take 200 mg

of Celebrex every other day instead of the 400 mg until I go off the

Celebrex again.

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Hello, Rainy! It's terrible that you are falling apart.

So sorry to hear about Lorette. How old was she? What other conditions did

she have in addition to her RA? What other meds did she take?

Celebrex (celecoxib) has never been removed, but Vioxx (rofecoxib) was

withdrawn voluntarily from the market by Merck in September 2004. They are

both COX-2 selective NSAIDs.

The biggest safety issue with the COX-2s has been the risk of cardiovascular

events.

They were developed to be safer for the GI tract than nonselective NSAIDs,

but, unfortunately, they too may cause GI injury. Other meds taken

concurrently, even aspirin, can contribute to the risk of gastropathy with

the COX-2s.

I'll post some information on this over the weekend.

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

[ ] Celebrex & Vioxx

Hello to all my friends. Hello to all those who don't know me. I joined this

list back in, I think it was 2000. I am still alive and ticking, however,

when I get my pulse taken, they can't find it in my wrist anymore! That one

makes for good jokes when it comes to going to the doctor! I just redirect

them to my neck.

How am I? Let's just leave it at this today, my body is falling apart. :)

I am working on repairs. But I am keeping a strong attitude and keep on

pushing forward. That is all we can do, right? This spring marks 24 years

when I first noticed my right knee swollen while I was in PE in the 7th

grade. I was 13 years old. I can't believe how long it has been!

I am looking for some info and personal experience on these two drugs.

Recently a friend of mine died, my ex-boyfriends grandmother. I am very

close with his mother, boyfriend and I were together 14 years, so she has

asked me for help on research. After Lorette died, my friend discovered that

one of the health problems her mother was suffering from was intestinal

bleeding. Two of the drugs she had taken previously were Celebrex and Vioxx.

I don't know for how long Lorette had taken them. But she took them for RA

and some really bad back pain. I remember at the time when this all came out

and they took them off the shelf and mentioned this to my boyfriend and his

mother at the time bcs it concerned me. I am actually not surprised for my

friend to be asking for help on research now.

Does anyone have any previous experience with this?

Or does anyone have any really great site that would help me?

How is everyone? ? a? Me-Mom?

I love you all!

RainySue

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Hi ! How are you?? And thank you for your help. I knew I could count on you!

I have been one of those very quiet and lurking members for quite some time now.

But I am here, I just blend in with the wallpaper!

Hmm, last November Lorette had a heart attack, but didn't know it. Her

daughter took her to the ER about 3 days after the attack bcs she didn't look

right. Her daughter found a huge bruise on her back and Lorette said that she

had fallen, tripped over the cat. We knew that wasn't entirely true once we

found out abt the heart attack. Apparently it must have been very mild. She left

us in January, she was 86. In fact, she left us on the 19th. My anniversary with

her grandson - we were together 14 years.

I don't know of any other meds at this time or even how long she had taken

those others. I am waiting now for more info. Except, I think she was taking

prednisone, but she only took like 2 or 3 mg when she took that. I don't think

she took it all the time.

I did find Celebrex has a rare side effect that includes intestinal bleeding:

http://www.healthsquare.com/newrx/CEL1078.HTM

Thank you, !

~RainySue

---------------------------------

Messenger with Voice. Make PC-to-Phone Calls to the US (and 30+

countries) for 2¢/min or less.

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RainySue, I will keep you in my prayers, Tawny

>

> Hello to all my friends. Hello to all those who don't know me. I

joined this list back in, I think it was 2000. I am still alive and

ticking, however, when I get my pulse taken, they can't find it in my

wrist anymore! That one makes for good jokes when it comes to going

to the doctor! I just redirect them to my neck.

>

> How am I? Let's just leave it at this today, my body is falling

apart. :) I am working on repairs. But I am keeping a strong attitude

and keep on pushing forward. That is all we can do, right? This

spring marks 24 years when I first noticed my right knee swollen

while I was in PE in the 7th grade. I was 13 years old. I can't

believe how long it has been!

>

> I am looking for some info and personal experience on these two

drugs. Recently a friend of mine died, my ex-boyfriends grandmother.

I am very close with his mother, boyfriend and I were together 14

years, so she has asked me for help on research. After Lorette died,

my friend discovered that one of the health problems her mother was

suffering from was intestinal bleeding. Two of the drugs she had

taken previously were Celebrex and Vioxx. I don't know for how long

Lorette had taken them. But she took them for RA and some really bad

back pain. I remember at the time when this all came out and they

took them off the shelf and mentioned this to my boyfriend and his

mother at the time bcs it concerned me. I am actually not surprised

for my friend to be asking for help on research now.

>

> Does anyone have any previous experience with this?

>

> Or does anyone have any really great site that would help me?

>

> How is everyone? ? a? Me-Mom?

>

> I love you all!

> RainySue

>

>

> ---------------------------------

> How low will we go? Check out Messenger's low PC-to-Phone

call rates.

>

>

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Good luck on your cataract surgery Thursday, Lynn!

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

Re: [ ] Celebrex & Vioxx

> Hello Rainy,

> Sorry it has taken me awhile to answer your note. Sorry things have been

> hard for you. I was allergic to Celebrex and Vioxx that was a mess. It

> raised my blood pressure so high. I found out right here on the list what

> was causing the problem When I ask the doctors they didn't believe me,

> reluctantly took me off the Vioxx. Thank God, I would have been in real

> trouble if I had stayed on the drug.

> I'm having my eye operated on Thursday. I have cataracts and they are

> telling me it is from all the years of taking the predisone. I didn't

> know

> it would cause this when I started taking it. I am right now trying to

> come

> off of it and there is a major difference in the pain level.

> What are you currently taking for the Ra. If I remember right you were on

> Remicade. I thought it was really helping you. It is great hearing from

> you but I feel bad that you are having so many problems. The loss of a

> friend is hard.

> Let me know how you are and if you have had any luck with the drug

> information.

> So glad to hear from you,

> MeMom

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