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REVIEW - Assessment of fracture risk

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Osteoporos Int. 2005 Jun;16(6):581-9. Epub 2004 Dec 23.

Assessment of fracture risk.

Kanis JA, Borgstrom F, De Laet C, Johansson H, ell O, Jonsson B, Oden A,

Zethraeus N, Pfleger B, Khaltaev N.

Centre for Metabolic Bone Diseases (WHO Collaborating Centre), University of

Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.

w.j.pontefract@...

The diagnosis of osteoporosis is based on the measurement of bone mineral

density (BMD). There are a number of clinical risk factors that provide

information on fracture risk over and above that given by BMD. The

assessment of fracture risk thus needs to be distinguished from diagnosis to

take account of the independent value of the clinical risk factors. These

include age, a prior fragility fracture, a parental history of hip fracture,

smoking, use of systemic corticosteroids, excess alcohol intake and

rheumatoid arthritis. The independent contribution of these risk factors can

be integrated by the calculation of fracture probability with or without the

use of BMD. Treatment can then be offered to those identified to have a

fracture probability greater than an intervention threshold.

PMID: 15616758

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=15616758

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

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