CASE REPORT - Brachial plexitis and myelitis and herpes-zoster lumbar plexus disorder in a patient treated with Remicade

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Neurologia. 2005 Sep;20(7):374-6.

[brachial plexitis and myelitis and herpes-zoster lumbar plexus disorder in

patient treated with infliximab]

[Article in Spanish]

Arias M, Arias-Rivas S, Dapena D, Mera A.

Servicio de Neurologia, Complejo Hospitalario Universitario de Santiago de

Compostela, La Coruna. mariasg@...

Infliximab, a chimeric monoclonal antibody, is a TNF-a inhibitor approved

for use in refractory rheumatoid arthritis and Crohn s disease. We present

the case of a patient affected by severe rheumatoid arthritis who was

successfully treated with infliximab. She suffered diverse neurological

complications: brachial plexitis, asymptomatic thoracic myelitis with

extensive lesions in MRI study, and herpes zoster lumbar plexitis. We review

the neurological adverse effects of infliximab (aseptic meningitis,

opportunistic germs infections, disseminated herpes zoster) and focus in

their potential adverse effect to induce central and peripheral nervous

system demyelination.

PMID: 16163582

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=16163582 & itool=iconabstr & query_hl=20 & itool=pubmed_DocSum

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