REVIEW - Does systemic-onset juvenile idiopathic arthritis belong under JIA?

[Guest guest]

Rheumatology (Oxford). 2005 Nov;44(11):1350-3. Epub 2005 Jun 14.

Does systemic-onset juvenile idiopathic arthritis belong under juvenile

idiopathic arthritis?

Ramanan AV, Grom AA.

Department of Paediatric Rheumatology, North Bristol NHS Trust & Royal

National Hospital for Rheumatic Diseases, Bath, UK. avramanan@...

'Science is the systematic classification of experience' Henry Lewes

(1817-78), English philosopher, critic, dramatist, scientist. Juvenile

idiopathic arthritis (JIA) is prevalent in about 1 in 1000 children. The

earliest formal description of this disease was by Sir Frederick

Still in 1897. This work was done when he was a registrar at the Hospital

for Sick Children, Great Ormond Street, London. In this initial description

of 19 patients he identified three patterns of arthritis, one of which came

to be known later as Still's disease [now known as systemic-onset juvenile

idiopathic arthritis (SoJIA)]. Over the next few decades it came to be

appreciated that one form of arthritis in children is very different and

dominated by the presence of systemic manifestations. Over the last two

decades several paediatric rheumatologists have come together to classify

juvenile arthritis for purposes of better disease identification and

research. All along, the systemic form of juvenile arthritis was always

recognized as belonging to a distinct group; in fact for several decades

(and even now in some countries) the systemic form of juvenile arthritis was

referred to as Still's disease. In this article we will attempt to highlight

the reasons why we feel that SoJIA is perhaps not best retained in the

company of JIA.

PMID: 15956091

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=15956091

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org