CASE REPORT - Twenty-year remission of RA in 2 patients after allogenic bone marrow transplant

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Case Report

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Twenty-year Remission of Rheumatoid Arthritis in 2 Patients After Allogeneic

Bone Marrow Transplant

RAY M. LOWENTHAL, HILTON FRANCIS, and DEVINDER S. GILL

ABSTRACT.

We describe 21 and 19 year followup of 2 patients with severe rheumatoid

arthritis (RA) who in 1984 and 1986 underwent allogeneic bone marrow

transplantation (BMT) after full myeloablative conditioning, for

therapy-induced aplastic anemia. Regarding the arthritis, both patients are

well, taking no medications, and free of signs or symptoms of active RA. One

patient is in excellent health overall, while the other has coronary artery

disease and chronic obstructive pulmonary disease attributable to smoking.

We suggest that allogeneic BMT may be a curative treatment for severe RA. (J

Rheumatol 2006;33:812-3)

http://www.jrheum.com/abstracts/abstracts06/812.html

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Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

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