Kineret

[Guest guest]

> Kineret was just approved by the FDA for RA - its made by Amgen,

the same

> company that just got Enbrel. My husbands PA said that they were

part of a

> study for Kineret and they loved it. Does anyone have any info on

this, or

> heard any comments?

>

> HAPPY HOLIDAYS!!!

> ELLIE

>

>

>I realize this is a late reply to those considering Kineret. At my

visit to my rheumatologist this past week he encouraged me to give it

a try. It is a self injectaable once a day medication. It works

against Interleukin - 1 .

I am having other problems right now such as a huge Sjogrens

syndrome flare, and I am recovering from a hospitalization from a

sinus surgery and subsequent rehospitilization for a large blood clot

in my right arm. I told him I wanted to wait a few months, cut out

the Arava, and see if I can just stay on the Imuran with out getting

much worse. Pain is now 8 on a scale of 1-10. I don't feel

comfortable mixing up all these hi power drugs together, and

especially so when my body is in such a state of flux.

If I do go on Kineret and have any results good or bad, you all will

be the first to know.

group founder

[Guest guest]

-,

I am sorry to hear about what you are going through at this time, you

would think there would be an end to 'at least' some of the problems

associated with PA... It would be great to have a 'break' from PA.

I, and I am sure this entire family of PA site friends, wish you all

the best and a quick recovery... and a major decrease in pain. #2

-- In @y..., " psoriaticarthur99 "

<PsoriaticArthur@a...> wrote:

>

> > Kineret was just approved by the FDA for RA - its made by Amgen,

> the same

> > company that just got Enbrel. My husbands PA said that they were

> part of a

> > study for Kineret and they loved it. Does anyone have any info on

> this, or

> > heard any comments?

> >

> > HAPPY HOLIDAYS!!!

> > ELLIE

> >

> >

> >I realize this is a late reply to those considering Kineret. At

my

> visit to my rheumatologist this past week he encouraged me to give

it

> a try. It is a self injectaable once a day medication. It works

> against Interleukin - 1 .

>

> I am having other problems right now such as a huge Sjogrens

> syndrome flare, and I am recovering from a hospitalization from a

> sinus surgery and subsequent rehospitilization for a large blood

clot

> in my right arm. I told him I wanted to wait a few months, cut out

> the Arava, and see if I can just stay on the Imuran with out

getting

> much worse. Pain is now 8 on a scale of 1-10. I don't feel

> comfortable mixing up all these hi power drugs together, and

> especially so when my body is in such a state of flux.

> If I do go on Kineret and have any results good or bad, you all

will

> be the first to know.

>

>

> group founder

[Guest guest]

Hi,

I am fairly new to the group and am on Kineret. I've been on it for 3

weeks and am on Plaquinil, Arava and Celebrex for PA, RA, Lupus and

P. So far the side effects most noticible with the Kineret are severe

rash and itching at the injection site. It takes a day or two for the

rash to show up and then a couple weeks for it to go away. Kineret

has a self injection aid called SimpleJect that I recommend for

anyone going on this med. I find the injections to be very painful

and couldn't keep doing it if I had to push the plunger myself. My Dr

says that it takes up to 4 weeks of taking the medication to know if

it's working. I also have to go in for blood tests every 4 weeks to

make sure my immune system isn't adversly affected by this med.

Looking back the three weeks I don't see any change in my condition,

I'm hoping that I notice some improvement soon (even if it is just a

little). If there is anyone else on this med I'd love to know how

you are doing. I haven't been able to find anyone else so far and am

going on what Amgen and my Dr are saying. It would be nice to hear

another person's expierence.

Amy

> > Kineret was just approved by the FDA for RA - its made by Amgen,

> the same company that just got Enbrel. My husbands PA said that

they were part of a study for Kineret and they loved it. Does anyone

have any info on this, or heard any comments?

> >

> > HAPPY HOLIDAYS!!!

> > ELLIE

> >

> >

[Guest guest]

Hi,

I am fairly new to the group and am on Kineret. I've been on it for 3

weeks and am on Plaquinil, Arava and Celebrex for PA, RA, Lupus and

P. So far the side effects most noticible with the Kineret are severe

rash and itching at the injection site. It takes a day or two for the

rash to show up and then a couple weeks for it to go away. Kineret

has a self injection aid called SimpleJect that I recommend for

anyone going on this med. I find the injections to be very painful

and couldn't keep doing it if I had to push the plunger myself. My Dr

says that it takes up to 4 weeks of taking the medication to know if

it's working. I also have to go in for blood tests every 4 weeks to

make sure my immune system isn't adversly affected by this med.

Looking back the three weeks I don't see any change in my condition,

I'm hoping that I notice some improvement soon (even if it is just a

little). If there is anyone else on this med I'd love to know how

you are doing. I haven't been able to find anyone else so far and am

going on what Amgen and my Dr are saying. It would be nice to hear

another person's expeirence.

Amy

> > Kineret was just approved by the FDA for RA - its made by Amgen,

> the same company that just got Enbrel. My husbands PA said that

they were part of a study for Kineret and they loved it. Does anyone

have any info on this, or heard any comments?

> >

> > HAPPY HOLIDAYS!!!

> > ELLIE

> >

> >

[Guest guest]

In a message dated Tue, 30 Apr 2002  3:52:28 PM Eastern Daylight Time, " Amy

-Sansotta " <andra@...> writes:

>Hi all,

>

>How are the other folks on Kineret doing? I saw my Rheumy last week and the

>results weren't promising. He wants to give Kineret another month and then

>we're going to have to look to something else. He switched a couple other

>meds hoping to find the right combination. He's not going to even look at

>enbrel until they get their situation sorted out and he doesn't think I'm a

>good candidate for Remicade.

I'm on Kineret right now. It worked amazingly well for the first three weeks

and now...*sigh* not so great. The swelling went way down and a lot of the

pain, but it's started to rebound this last week. I've been having some really

achy nights and waking up with sore knees, which I didn't have the first few

weeks. We did have two separate low pressure systems park right over top of us

at the moment. grr! On the plus side, I'm finally getting through the break

out stage with it. Most of the rashs are going down.

Smile,

Becky

[Guest guest]

I'm afraid the Kineret isn't really working for me either. My

alternative is Remicade I'm afraid. I don't know how I will do with

that...pass out I'm sure.

> Hi Janine and all

> I took Kineret for 3 months and had no improvement at all. My

right

> hand and fingers are severly swollen and it didn't help them at all.

> Even the drug company told my rheumy to stop it because they

usually see

> improvement by 6 weeks. I saw her yesterday and she told me she had

6

> people on it at the same time as me and only one had slight

improvement,

> so she is not too impressed with the drug. She has spoken to other

docs

> who are seeing the same kind of results. I have tried every

available

> drug in the last 3 and 1/2 years and nothing works for me. She said

> there is a new biologic agent due to be released...not sure

> when....maybe not until the first of 2003. It doesn't have a name

yet,

> only numbers. It is an injectible. So I will wait to try it. Hope

you

> have better luck than me. We are all different. What works for some

> doesn't help others. The doc said she has a couple of other patients

> like me that don't respond to anything, so go figure! Waiting for a

> miracle!

>

>

>

> [Moderator's note: Is the new drug you mentioned named " D2E7 " ? If

so, xmac23 who works for the pharmaceutical company producing the

drug posted about it at:

/message/22026

> -- Ron]

[Guest guest]

> I'm afraid the Kineret isn't really working for me either. My

> alternative is Remicade I'm afraid. I don't know how I will do with

> that...pass out I'm sure.

Have taken first two treatments on Remicade--both treatments absolutely

could not have been a better experience! I learned long time ago not to

look at needles inserted in my hand/arm so, arm was covered--nurse would

check and put covering back. You are on monitor, plus the nurses are at a

station where they can see every infusion patient all the time and you can

speak to them at any time. They offer sodas, etc., snacks or even lunch (TV

dinner). Also, a small TV is provided to every patient that decides he or

she wants one.

Now, about the best part--my improvement began immediately: husband noticed

increased energy immediately upon my return home. After dinner, I went

upstairs (first time since February) and got on the computer--signed back

up for this site, caught up on e-mails, etc. My husband was amazed. I was

on 15 mg Prednisone, Vioxx (2Xday) and Darvocet (two pills, 3Xday) when I

began infusions. Now taking 7.5 mg. prednisone, Vioxx (same) and only

occasionally take Darvocet. Things are not perfect - or believe me, I would

not be taking Prednisone at all, but overall we are very encouraged.

I go back to rheumatologist tomorrow (first visit since began infusions)

and I plan to ask him about taking arava instead of prednisone. I took

arava for two years with excellent results (even assisted me in losing 57

pounds I had gained while on Methotrexate and prednisone for 6-1/2 years)

until both knees became inflamed and methotrexate prescribed in addition to

arava. I had such serious side effects from combination it was determined

I could never take Methotrexate again because side effects were consistent

with those predicted in " rare " cases from Methotrexate. Anyway, apparently

some people take arava instead of Methotrexate with Remicade and are able to

get off of prednisone the same way I did when on Arava before.

I wish you the best no matter how you decide to proceed with treatment.

Just had to write and share my experience because I had same sense of dread

before beginning infusions. I actually started treatments because embrel

not available until 2003. Now, given my positive experience so far, I plan

to stick with the Remicade until it either doesn't work anymore, or I have

undesirable side effects. Rheumy explained can always switch to embrel due

to its recommendation for PA--of course, that is, if it is

vailable! -- in VA

[ ] Re: Kineret

>

>

> > Hi Janine and all

> > I took Kineret for 3 months and had no improvement at all. My

> right

> > hand and fingers are severly swollen and it didn't help them at all.

> > Even the drug company told my rheumy to stop it because they

> usually see

> > improvement by 6 weeks. I saw her yesterday and she told me she had

> 6

> > people on it at the same time as me and only one had slight

> improvement,

> > so she is not too impressed with the drug. She has spoken to other

> docs

> > who are seeing the same kind of results. I have tried every

> available

> > drug in the last 3 and 1/2 years and nothing works for me. She said

> > there is a new biologic agent due to be released...not sure

> > when....maybe not until the first of 2003. It doesn't have a name

> yet,

> > only numbers. It is an injectible. So I will wait to try it. Hope

> you

> > have better luck than me. We are all different. What works for some

> > doesn't help others. The doc said she has a couple of other patients

> > like me that don't respond to anything, so go figure! Waiting for a

> > miracle!

> >

> >

> >

> > [Moderator's note: Is the new drug you mentioned named " D2E7 " ? If

> so, xmac23 who works for the pharmaceutical company producing the

> drug posted about it at:

> /message/22026

> > -- Ron]

>

>

>

>

>

[Guest guest]

Hi ,

Here are a few links that you may want to look at, or forward, for more

detailed information for your brother. Let him know that we're thinking

of him, sending good wishes, and hoping that this treatment will be the

one that works!

Aloha,

Georgina

**************************************

For free hands-on Support Services and Resources, call:

1-866-KINERET (1-866-546-3738 toll free)

For online resources, see:

http://www.kineretrx.com/patient/

http://arthritisinsight.com/medical/meds/kineret.html

http://www.arthritisinsight.com/community/stories/tina4.html

http://wwwext.amgen.com/

******************************************

WILLIAM PRICE wrote:

Anybody out there with

any info about kineret? My brother has pretty bad RA and hopes to

start on kineret. He has already given mtx and enbrel a try.

thanks, (n, 14, systemic)

[Guest guest]

Hello everyone, I am fairly new to RA. I was diagnoised in Feb 06 but

my Rhuemy believes that I have had it since Oct 04. We have tried the

first round of drugs with no luck. MTX is not providing enough relief.

I will be starting Kineret next week, my insurance company just

approved it. I was wondering if anyone has had great luck with

Kineret. I know that it is daily shots but my Dr. feels that this will

be the best choice for me. I have a problem with recurring unrinary

infections and she feels that if I need to go on an antibiotics that

Kineret would get out of my system faster than the weekly drugs.

If you have used or are currently on Kineret, I would love to hear your

thoughts. Thanks, Beth

[Guest guest]

Holly also still has a bad time dealing with the enbrel shots, and is hoping

against hope that she wont have to go to kineret. She is doing better with

them now, she doesn't fight me the whole way and cry for hours

anymore..........but she still gets upset about it some of the time.

n and Holly

12 years old (soon to be a teenager....eek!!!! December 22)

systemic jra since 9/94