Guest guest Posted April 3, 2008 Report Share Posted April 3, 2008 Sorry to hear that. Yes - it's very frustrating. This phenomenon is referred to as penile anaesthesia by the medics and seems to be a common feature of the PSSD syndrome. How it happens is still completely unknown, as is the treatment. We have been damaged, probably by taking SSRIs, and there is not a lot we can do about it yet... This website is part of the effort to find answers. K. > > I'm getting fed up of this crap! Does anyone else penis glans feel > like just regular skin on their finger somethimes. I can't even feel > the sensation of my shaft and frenulum! I dont understand how i can > sustain an erections or get erections even though I cant feel anything > sometimes. I would appreciate if some members talk about their > experience with this problem. Thank you. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 3, 2008 Report Share Posted April 3, 2008 Penile anesthesia, is almost certainly caused by neurological damage of some sort. Beyond that we cannot say. Incidentally, when I tried to tell my neurologist about my penile anesthesia, he didn't quite understand what I meant. He proceeded to stick a pin in my penis, and asked me if it hurt. I said yes, it certainly did! He then asked me how it could hurt if it was numb! I told him that touching my penis feels like touching my thumb, no better, and no worse. He was baffled! Planning your summer road trip? Check out AOL Travel Guides. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 4, 2008 Report Share Posted April 4, 2008 i have this problem, not quite as severely but it actually started prior to anti-depressant use and has inevitably gotten worse from ssri's. tyrosine made a big difference till it stopped working. gave me hope that some sensitivity will return but who knows. it definitely sucks! > > I'm getting fed up of this crap! Does anyone else penis glans feel > like just regular skin on their finger somethimes. I can't even feel > the sensation of my shaft and frenulum! I dont understand how i can > sustain an erections or get erections even though I cant feel anything > sometimes. I would appreciate if some members talk about their > experience with this problem. Thank you. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2008 Report Share Posted April 6, 2008 Have you had your testosterone levels checked? Mine are a bit low and I have this problem. My understanding is that low testosterone can cause this. ~ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2008 Report Share Posted April 8, 2008 I checked my testosterone twice, both times normal. Actually the second it was actually high. > > Have you had your testosterone levels checked? Mine are a bit low and > I have this problem. My understanding is that low testosterone can > cause this. > > ~ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2008 Report Share Posted April 8, 2008 Did you have your free testosterone checked? From what I know (and I am not a doc) free testosterone is a very important, if not the MOST important, part of the equation for this stuff. So I would suggest you get that checked. Joe > > > > Have you had your testosterone levels checked? Mine are a bit low and > > I have this problem. My understanding is that low testosterone can > > cause this. > > > > ~ > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 These problems start getting a bit better after cannibs use and also after use of nutmeg. They also got a lot better after taking MDMA (extasy). I think the problems are possibly cause by the 5ht1a system and the 5ht2a system, as opposed to the dopamine system as most people on the group believe. The 5ht1a system is responsible for awakene feelings and also orgasm arousal and the 5ht2a and 2c systems also play a role in orgasm and also probably for signalling erections. Obviously, the dopamine system is also involved to an extent. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 what exact dosage of nutmeg did you take ? do you take them regularly ? Ive read online it shouldnt be taken too much and cause hallucinations. > > These problems start getting a bit better after cannibs use and also > after use of nutmeg. They also got a lot better after taking MDMA > (extasy). I think the problems are possibly cause by the 5ht1a system > and the 5ht2a system, as opposed to the dopamine system as most people > on the group believe. > > The 5ht1a system is responsible for awakene feelings and also orgasm > arousal and the 5ht2a and 2c systems also play a role in orgasm and > also probably for signalling erections. > > Obviously, the dopamine system is also involved to an extent. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 watch this guy trying out nutmeg. he says it took much later to notice the effects. Also he mentions on 4th page that he noticed heighted physical sensitivity. I want to give it a try but not sure how much to take to prevent hallucinations. " it lasted about a day and a half. the first 5 hours were an intense high and then the rest of it after was just giggles and heightened sensitivity to physical stimuli. " http://www.youtube.com/watch?v=GsNK_9TfKGE & feature=related > > > > These problems start getting a bit better after cannibs use and also > > after use of nutmeg. They also got a lot better after taking MDMA > > (extasy). I think the problems are possibly cause by the 5ht1a system > > and the 5ht2a system, as opposed to the dopamine system as most > people > > on the group believe. > > > > The 5ht1a system is responsible for awakene feelings and also orgasm > > arousal and the 5ht2a and 2c systems also play a role in orgasm and > > also probably for signalling erections. > > > > Obviously, the dopamine system is also involved to an extent. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 Ya that's kinda the point or some people. and cause hallucinations. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 I'm not sure I asked this question before. Do some people here feel numbness at times to the point that their penis is less receptive to pain? Also my testicles dont feel pleasurable to touch as well. Has anyone been cured of this overtime??? > and cause hallucinations. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2008 Report Share Posted April 10, 2008 This is what I understand as well. You can have your total testosterone just fine, but other factors can cause your body not to be able to use it. These include estrogen dominance, for example. http://209.85.173.104/search?q=cache:kVOXBwzbcigJ:www.allthingsmale.com/word_doc\ s/TRT.doc+trt+recipe+for+success & hl=en & ct=clnk & cd=3 & gl=us & client=firefox-a - It details some of the different chemicals that can be messed up causing low testosterone symptoms. Most of them are testable, so I'd recommend getting some or all of them checked out if you still suspect a testosterone problem. Some of these things are easily treatable once you figure out what they are. If you'd like a forum on these kinds of things, go to www.musclechatroom.com and check out the " All Things Male " section. So far we can't figure out why my testosterone is low, but I have the same sensation problem you do - my genitals just feel like any other part of my body. It may or may not be soley because of the medications (or at all), but other posters here have found testosterone problems, and I HAVE seen this listed as a symptom for low testosterone. Low libido definitely is as well. From what I can tell, low Free or another problem could have the same effect. I may go on supplementation down the road. We'll see. ~ > > > > > > Have you had your testosterone levels checked? Mine are a bit low and > > > I have this problem. My understanding is that low testosterone can > > > cause this. > > > > > > ~ > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 11, 2008 Report Share Posted April 11, 2008 I only took a little bit of nutmeg. Overall cannibis seems to be better, to my surprise. Cannibis mainly acts on the 5ht1a receptors. It improves orgasm pretty quickly, and also makes you much more interested in sex. It blocks dopamine as well, which I suppose could cause dopamine to stockpile? But in my experience, pssd is possibly cause by problems with specific receptors, and not just " low dopamine. " I have seen many dopamine meds tried, and none of them really work for long. The nutmeg seemed to work better for a few days after drinking alcahol. However, cannibis tea still comes over as much better. Its possible that a combination of the two would have much better effects. One interesting side effect of nutmeg, which I had expected, was that it caused my dreams to return completely. This is probably due to activation of the 5ht2a receptors. To my surprise, cannibis also caused enhanced REM sleep (possiboy sue to dopamine or canaboid rectors?). Enhancement of the 5ht1a receptors should really block REM sleep. The other thing that seems to improve libido and softens the penis is the comedown from alcahol, which acts on serotonin, gaba and dopamine. I do not know whether it acts oin specific receptors or not. Serotonin is very specific and some of the recptors heighten libido, whilst others weaken it. However, i will not give up this line of enquiry at present. I have had some interesting results. More interesting overall than with muccuna puriens or bupropion alone. Certainly cannibis is pretty effective at alleviating the depression and loss of libido caused by pssd, particularly when taken as a tea and not taken too much. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 11, 2008 Report Share Posted April 11, 2008 You should treat this stuff with extreme caution. It really is " toxic " as the litterature suggests. I think it needs to be augmented with something else, as it only worked properly after alcahol. If you took this stuff all the time you would get liver damage. Anything that enhances serotonin receptors can cause hallucinations. Cannibis can cause hallucinations. I only took a teaspoon full. This did not cause hallucinaitons. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 11, 2008 Report Share Posted April 11, 2008 I found that extacy improved all of these problems and I could get normal feeling erections again. In fact, this kicked in just at the end of the mid week blues, and lasted a few days. I don't know what caused this, but I expect it was something to do with specific serotonin disorders. Alternatively, it could have been somethig entirely unconnected such as change in sleep etc. However, I also had a similar experience another time, on the night when I was taking extacy. I thnk MDMA mainly enhances 5ht2 and 5ht1a receptors. It also raises oxytocin levels, has an effect on dopamine, raises nitric oxide synthase, and also effects muscarinic receptors. So it hardly surprising that it can have a positive effect on libido. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 11, 2008 Report Share Posted April 11, 2008 I guess that this effect of extasy is just short term? If extasy can diminish PSSD symptoms can be much better evaluated if this experiment is repeated ten or twenty times. There is a risk that extacy is polluted with unhealthy ingredients, since its production is not supervised by the authorities. > > I found that extacy improved all of these problems and I could get > normal feeling erections again. In fact, this kicked in just at the end of the mid week blues, and lasted a few days. > > I don't know what caused this, but I expect it was something to do with > specific serotonin disorders. Alternatively, it could have been > somethig entirely unconnected such as change in sleep etc. > > However, I also had a similar experience another time, on the night > when I was taking extacy. I thnk MDMA mainly enhances 5ht2 and 5ht1a > receptors. It also raises oxytocin levels, has an effect on dopamine, > raises nitric oxide synthase, and also effects muscarinic receptors. So > it hardly surprising that it can have a positive effect on libido. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2008 Report Share Posted April 12, 2008 No, no and no. We should not be taking MDMA in regular experikments because it is toxic. The libido effects seemed to last for up to 7 days after the first time of use. Pure MDMA is very rarely mixed with other substances, but the price is put up instead. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2008 Report Share Posted April 13, 2008 MDMA does not diminish symptoms of pssd, it completely releives all symptoms of pssd. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2008 Report Share Posted May 2, 2008 I'm well aware of what penile anaethesia is. My glans (before sensitive)feels like any other normal skin on my body. I cant even feel my frenulum (most sensitive part of the penis) its as if all the nerve endings in penis are gone. I cant even feel pain there as I did before. The sensivity also fluctuates, for example, some days it better than others. I did full blood work from urologists, everything was normal. I even did a bulborous reflex test with an electrical current. (Usually done for people suffering from neuropathy), again normal. My full sensitivity came back for 2-3 days in September. Did nothing special for that to happen. My two questions are 1) Any men having sex here who have this problem? How does it feel and how do you cope with this? 2)Women are 10 X more likely than men to take antidepressants, how come we dont see an equal if not more number of women on this forum. > > > > > > > > Have you had your testosterone levels checked? Mine are a bit > low and > > > > I have this problem. My understanding is that low testosterone can > > > > cause this. > > > > > > > > ~ > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 3, 2008 Report Share Posted May 3, 2008 It is not because the nerve endings are " gone. " Ive found that using nutmeg/MDMA/cannibis somewhat lessens this problem. It is probably mainly to do with specific serotonin neurons, dopamine, and nitric oxide. It is not nerve dmaage as some people have previously insinuated. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 9, 2008 Report Share Posted July 9, 2008 Dear pssd24 I have heard from a few people who have taken extacy that it has improved their sex drive and sensitivity in ways not felt prior so i have always been curious about it but never considered using it often. After reading were you said that it stopped your pssd completely for a while after using it and that it was the real thing, that curiousity went WAY up. But then it went down after I read where you said that marijunia and alchohol had similar effects. A lot of my family uses marijunia so I use it every now and then to be sociable but I really dont consider it worth more than that or worth forking out all the money for but it does relax you. I also am a social drinker. Neither one, by itself or in comination, has never increased my libido or orgasm in any noticeably significant way. Also most of what I have heard or read is that marijunia and alchohol, by theirselves or in combonation, if used excesively, can cause sexual dysfunction just like antidepressants. So my hopes went down after i read where it said that you got similar effects from weed, alchohol, nutmeg, etc. So I would really like to know if you are just getting peoples hopes up by advertising street drugs or are you really getting real results, better than the rest of us, and can you describe the differences between each? Thank you. Also to sssssssri. Sorry for not writing back after a couple of weeks. I've either been very busy with something or very depressed. But to answer your question - I dont know if the USA or what other countries have discontinued nefazodone, I was actually just talking about my hospital's pharmacy system. Also, to those who said that they've experienced suicidal thoughts - I must admit that I have had them at times. My hats off to you if it has never crossed your mind. But trying to stay strong and having good distractions and having hope that something can give is how I cope. > > I only took a little bit of nutmeg. Overall cannibis seems to be > better, to my surprise. > > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm pretty > quickly, and also makes you much more interested in sex. It blocks > dopamine as well, which I suppose could cause dopamine to stockpile? > But in my experience, pssd is possibly cause by problems with specific > receptors, and not just " low dopamine. " I have seen many dopamine meds > tried, and none of them really work for long. > > The nutmeg seemed to work better for a few days after drinking alcahol. > However, cannibis tea still comes over as much better. Its possible > that a combination of the two would have much better effects. > > One interesting side effect of nutmeg, which I had expected, was that > it caused my dreams to return completely. This is probably due to > activation of the 5ht2a receptors. > > To my surprise, cannibis also caused enhanced REM sleep (possiboy sue > to dopamine or canaboid rectors?). Enhancement of the 5ht1a receptors > should really block REM sleep. > > The other thing that seems to improve libido and softens the penis is > the comedown from alcahol, which acts on serotonin, gaba and dopamine. > I do not know whether it acts oin specific receptors or not. Serotonin > is very specific and some of the recptors heighten libido, whilst > others weaken it. > > However, i will not give up this line of enquiry at present. I have had > some interesting results. More interesting overall than with muccuna > puriens or bupropion alone. Certainly cannibis is pretty effective at > alleviating the depression and loss of libido caused by pssd, > particularly when taken as a tea and not taken too much. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 9, 2008 Report Share Posted July 9, 2008 I've always been curious about MDMA. And i've been really curious about trying it but I've been afraid because of it's action on serotonin receptors, I am weary if it would make my condition worse. But, I am looking to have a dramatic, epiphanic experience. I've got nothing to lose at this point. Also it is a very therapeutic drug, and it could make things better in the long run. I've been looking into things like mushrooms as well. I need something as a guiding force - too bring things into a different perspective. > > > > I only took a little bit of nutmeg. Overall cannibis seems to be > > better, to my surprise. > > > > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm > pretty > > quickly, and also makes you much more interested in sex. It blocks > > dopamine as well, which I suppose could cause dopamine to > stockpile? > > But in my experience, pssd is possibly cause by problems with > specific > > receptors, and not just " low dopamine. " I have seen many dopamine > meds > > tried, and none of them really work for long. > > > > The nutmeg seemed to work better for a few days after drinking > alcahol. > > However, cannibis tea still comes over as much better. Its > possible > > that a combination of the two would have much better effects. > > > > One interesting side effect of nutmeg, which I had expected, was > that > > it caused my dreams to return completely. This is probably due to > > activation of the 5ht2a receptors. > > > > To my surprise, cannibis also caused enhanced REM sleep (possiboy > sue > > to dopamine or canaboid rectors?). Enhancement of the 5ht1a > receptors > > should really block REM sleep. > > > > The other thing that seems to improve libido and softens the penis > is > > the comedown from alcahol, which acts on serotonin, gaba and > dopamine. > > I do not know whether it acts oin specific receptors or not. > Serotonin > > is very specific and some of the recptors heighten libido, whilst > > others weaken it. > > > > However, i will not give up this line of enquiry at present. I > have had > > some interesting results. More interesting overall than with > muccuna > > puriens or bupropion alone. Certainly cannibis is pretty effective > at > > alleviating the depression and loss of libido caused by pssd, > > particularly when taken as a tea and not taken too much. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 10, 2008 Report Share Posted July 10, 2008 You misunderstood. The main point I made was that cannibis helped me to sleep and made me feel more awake. MDMA increases vasporessin and oxytocin, which in turn makes more DHT and Prostaglandin. I have suggested several times that this completely stops pssd. > > > > I only took a little bit of nutmeg. Overall cannibis seems to be > > better, to my surprise. > > > > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm > pretty > > quickly, and also makes you much more interested in sex. It blocks > > dopamine as well, which I suppose could cause dopamine to > stockpile? > > But in my experience, pssd is possibly cause by problems with > specific > > receptors, and not just " low dopamine. " I have seen many dopamine > meds > > tried, and none of them really work for long. > > > > The nutmeg seemed to work better for a few days after drinking > alcahol. > > However, cannibis tea still comes over as much better. Its > possible > > that a combination of the two would have much better effects. > > > > One interesting side effect of nutmeg, which I had expected, was > that > > it caused my dreams to return completely. This is probably due to > > activation of the 5ht2a receptors. > > > > To my surprise, cannibis also caused enhanced REM sleep (possiboy > sue > > to dopamine or canaboid rectors?). Enhancement of the 5ht1a > receptors > > should really block REM sleep. > > > > The other thing that seems to improve libido and softens the penis > is > > the comedown from alcahol, which acts on serotonin, gaba and > dopamine. > > I do not know whether it acts oin specific receptors or not. > Serotonin > > is very specific and some of the recptors heighten libido, whilst > > others weaken it. > > > > However, i will not give up this line of enquiry at present. I > have had > > some interesting results. More interesting overall than with > muccuna > > puriens or bupropion alone. Certainly cannibis is pretty effective > at > > alleviating the depression and loss of libido caused by pssd, > > particularly when taken as a tea and not taken too much. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 10, 2008 Report Share Posted July 10, 2008 MDMA is quite neurotoxic, but this can be countered to a degree with high doses of various antioxidants (see erowid mdma faqs'). However, I still do not recommend it - I felt unwell for some time after trying it a few years ago... > > > > > > I only took a little bit of nutmeg. Overall cannibis seems to be > > > better, to my surprise. > > > > > > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm > > pretty > > > quickly, and also makes you much more interested in sex. It > blocks > > > dopamine as well, which I suppose could cause dopamine to > > stockpile? > > > But in my experience, pssd is possibly cause by problems with > > specific > > > receptors, and not just " low dopamine. " I have seen many dopamine > > meds > > > tried, and none of them really work for long. > > > > > > The nutmeg seemed to work better for a few days after drinking > > alcahol. > > > However, cannibis tea still comes over as much better. Its > > possible > > > that a combination of the two would have much better effects. > > > > > > One interesting side effect of nutmeg, which I had expected, was > > that > > > it caused my dreams to return completely. This is probably due to > > > activation of the 5ht2a receptors. > > > > > > To my surprise, cannibis also caused enhanced REM sleep (possiboy > > sue > > > to dopamine or canaboid rectors?). Enhancement of the 5ht1a > > receptors > > > should really block REM sleep. > > > > > > The other thing that seems to improve libido and softens the > penis > > is > > > the comedown from alcahol, which acts on serotonin, gaba and > > dopamine. > > > I do not know whether it acts oin specific receptors or not. > > Serotonin > > > is very specific and some of the recptors heighten libido, whilst > > > others weaken it. > > > > > > However, i will not give up this line of enquiry at present. I > > have had > > > some interesting results. More interesting overall than with > > muccuna > > > puriens or bupropion alone. Certainly cannibis is pretty > effective > > at > > > alleviating the depression and loss of libido caused by pssd, > > > particularly when taken as a tea and not taken too much. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 10, 2008 Report Share Posted July 10, 2008 > > > > > > I only took a little bit of nutmeg. Overall cannibis seems to be > > > better, to my surprise. > > > > > > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm > > pretty > > > quickly, and also makes you much more interested in sex. It > blocks > > > dopamine as well, which I suppose could cause dopamine to > > stockpile? > > > But in my experience, pssd is possibly cause by problems with > > specific > > > receptors, and not just " low dopamine. " I have seen many dopamine > > meds > > > tried, and none of them really work for long. > > > > > > The nutmeg seemed to work better for a few days after drinking > > alcahol. > > > However, cannibis tea still comes over as much better. Its > > possible > > > that a combination of the two would have much better effects. > > > > > > One interesting side effect of nutmeg, which I had expected, was > > that > > > it caused my dreams to return completely. This is probably due to > > > activation of the 5ht2a receptors. > > > > > > To my surprise, cannibis also caused enhanced REM sleep (possiboy > > sue > > > to dopamine or canaboid rectors?). Enhancement of the 5ht1a > > receptors > > > should really block REM sleep. > > > > > > The other thing that seems to improve libido and softens the > penis > > is > > > the comedown from alcahol, which acts on serotonin, gaba and > > dopamine. > > > I do not know whether it acts oin specific receptors or not. > > Serotonin > > > is very specific and some of the recptors heighten libido, whilst > > > others weaken it. > > > > > > However, i will not give up this line of enquiry at present. I > > have had > > > some interesting results. More interesting overall than with > > muccuna > > > puriens or bupropion alone. Certainly cannibis is pretty > effective > > at > > > alleviating the depression and loss of libido caused by pssd, > > > particularly when taken as a tea and not taken too much. > > > > > > Quote Link to comment Share on other sites More sharing options...
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