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Sorry to hear that. Yes - it's very frustrating. This phenomenon is

referred to as penile anaesthesia by the medics and seems to be a

common feature of the PSSD syndrome. How it happens is still

completely unknown, as is the treatment. We have been damaged,

probably by taking SSRIs, and there is not a lot we can do about it

yet... This website is part of the effort to find answers.

K.

>

> I'm getting fed up of this crap! Does anyone else penis glans feel

> like just regular skin on their finger somethimes. I can't even feel

> the sensation of my shaft and frenulum! I dont understand how i can

> sustain an erections or get erections even though I cant feel anything

> sometimes. I would appreciate if some members talk about their

> experience with this problem. Thank you.

>

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Penile anesthesia, is almost certainly caused by neurological damage of some sort. Beyond that we cannot say. Incidentally, when I tried to tell my neurologist about my penile anesthesia, he didn't quite understand what I meant. He proceeded to stick a pin in my penis, and asked me if it hurt. I said yes, it certainly did! He then asked me how it could hurt if it was numb! I told him that touching my penis feels like touching my thumb, no better, and no worse. He was baffled!

Planning your summer road trip? Check out AOL Travel Guides.

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i have this problem, not quite as severely but it actually started prior to

anti-depressant use

and has inevitably gotten worse from ssri's.

tyrosine made a big difference till it stopped working. gave me hope that some

sensitivity will

return but who knows. it definitely sucks!

>

> I'm getting fed up of this crap! Does anyone else penis glans feel

> like just regular skin on their finger somethimes. I can't even feel

> the sensation of my shaft and frenulum! I dont understand how i can

> sustain an erections or get erections even though I cant feel anything

> sometimes. I would appreciate if some members talk about their

> experience with this problem. Thank you.

>

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Have you had your testosterone levels checked? Mine are a bit low and

I have this problem. My understanding is that low testosterone can

cause this.

~

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I checked my testosterone twice, both times normal. Actually the

second it was actually high.

>

> Have you had your testosterone levels checked? Mine are a bit low and

> I have this problem. My understanding is that low testosterone can

> cause this.

>

> ~

>

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Did you have your free testosterone checked? From what I know (and I am not a

doc) free

testosterone is a very important, if not the MOST important, part of the

equation for this

stuff. So I would suggest you get that checked.

Joe

> >

> > Have you had your testosterone levels checked? Mine are a bit low and

> > I have this problem. My understanding is that low testosterone can

> > cause this.

> >

> > ~

> >

>

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These problems start getting a bit better after cannibs use and also

after use of nutmeg. They also got a lot better after taking MDMA

(extasy). I think the problems are possibly cause by the 5ht1a system

and the 5ht2a system, as opposed to the dopamine system as most people

on the group believe.

The 5ht1a system is responsible for awakene feelings and also orgasm

arousal and the 5ht2a and 2c systems also play a role in orgasm and

also probably for signalling erections.

Obviously, the dopamine system is also involved to an extent.

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what exact dosage of nutmeg did you take ? do you take them regularly ?

Ive read online it shouldnt be taken too much and cause hallucinations.

>

> These problems start getting a bit better after cannibs use and also

> after use of nutmeg. They also got a lot better after taking MDMA

> (extasy). I think the problems are possibly cause by the 5ht1a system

> and the 5ht2a system, as opposed to the dopamine system as most

people

> on the group believe.

>

> The 5ht1a system is responsible for awakene feelings and also orgasm

> arousal and the 5ht2a and 2c systems also play a role in orgasm and

> also probably for signalling erections.

>

> Obviously, the dopamine system is also involved to an extent.

>

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watch this guy trying out nutmeg. he says it took much later to

notice the effects. Also he mentions on 4th page that he noticed

heighted physical sensitivity. I want to give it a try but not sure

how much to take to prevent hallucinations.

" it lasted about a day and a half. the first 5 hours were an intense

high and then the rest of it after was just giggles and heightened

sensitivity to physical stimuli. "

http://www.youtube.com/watch?v=GsNK_9TfKGE & feature=related

> >

> > These problems start getting a bit better after cannibs use and

also

> > after use of nutmeg. They also got a lot better after taking MDMA

> > (extasy). I think the problems are possibly cause by the 5ht1a

system

> > and the 5ht2a system, as opposed to the dopamine system as most

> people

> > on the group believe.

> >

> > The 5ht1a system is responsible for awakene feelings and also

orgasm

> > arousal and the 5ht2a and 2c systems also play a role in orgasm

and

> > also probably for signalling erections.

> >

> > Obviously, the dopamine system is also involved to an extent.

> >

>

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I'm not sure I asked this question before. Do some people here feel

numbness at times to the point that their penis is less receptive to

pain? Also my testicles dont feel pleasurable to touch as well. Has

anyone been cured of this overtime???

> and cause hallucinations.

>

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This is what I understand as well.

You can have your total testosterone just fine, but other factors can

cause your body not to be able to use it. These include estrogen

dominance, for example.

http://209.85.173.104/search?q=cache:kVOXBwzbcigJ:www.allthingsmale.com/word_doc\

s/TRT.doc+trt+recipe+for+success & hl=en & ct=clnk & cd=3 & gl=us & client=firefox-a

- It details some of the different chemicals that can be messed up

causing low testosterone symptoms. Most of them are testable, so I'd

recommend getting some or all of them checked out if you still suspect

a testosterone problem. Some of these things are easily treatable once

you figure out what they are. If you'd like a forum on these kinds of

things, go to www.musclechatroom.com and check out the " All Things

Male " section.

So far we can't figure out why my testosterone is low, but I have the

same sensation problem you do - my genitals just feel like any other

part of my body. It may or may not be soley because of the medications

(or at all), but other posters here have found testosterone problems,

and I HAVE seen this listed as a symptom for low testosterone. Low

libido definitely is as well. From what I can tell, low Free or

another problem could have the same effect.

I may go on supplementation down the road. We'll see.

~

> > >

> > > Have you had your testosterone levels checked? Mine are a bit

low and

> > > I have this problem. My understanding is that low testosterone can

> > > cause this.

> > >

> > > ~

> > >

> >

>

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I only took a little bit of nutmeg. Overall cannibis seems to be

better, to my surprise.

Cannibis mainly acts on the 5ht1a receptors. It improves orgasm pretty

quickly, and also makes you much more interested in sex. It blocks

dopamine as well, which I suppose could cause dopamine to stockpile?

But in my experience, pssd is possibly cause by problems with specific

receptors, and not just " low dopamine. " I have seen many dopamine meds

tried, and none of them really work for long.

The nutmeg seemed to work better for a few days after drinking alcahol.

However, cannibis tea still comes over as much better. Its possible

that a combination of the two would have much better effects.

One interesting side effect of nutmeg, which I had expected, was that

it caused my dreams to return completely. This is probably due to

activation of the 5ht2a receptors.

To my surprise, cannibis also caused enhanced REM sleep (possiboy sue

to dopamine or canaboid rectors?). Enhancement of the 5ht1a receptors

should really block REM sleep.

The other thing that seems to improve libido and softens the penis is

the comedown from alcahol, which acts on serotonin, gaba and dopamine.

I do not know whether it acts oin specific receptors or not. Serotonin

is very specific and some of the recptors heighten libido, whilst

others weaken it.

However, i will not give up this line of enquiry at present. I have had

some interesting results. More interesting overall than with muccuna

puriens or bupropion alone. Certainly cannibis is pretty effective at

alleviating the depression and loss of libido caused by pssd,

particularly when taken as a tea and not taken too much.

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You should treat this stuff with extreme caution. It really is " toxic "

as the litterature suggests. I think it needs to be augmented with

something else, as it only worked properly after alcahol. If you took

this stuff all the time you would get liver damage.

Anything that enhances serotonin receptors can cause hallucinations.

Cannibis can cause hallucinations. I only took a teaspoon full. This

did not cause hallucinaitons.

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I found that extacy improved all of these problems and I could get

normal feeling erections again. In fact, this kicked in just at the end

of the mid week blues, and lasted a few days.

I don't know what caused this, but I expect it was something to do with

specific serotonin disorders. Alternatively, it could have been

somethig entirely unconnected such as change in sleep etc.

However, I also had a similar experience another time, on the night

when I was taking extacy. I thnk MDMA mainly enhances 5ht2 and 5ht1a

receptors. It also raises oxytocin levels, has an effect on dopamine,

raises nitric oxide synthase, and also effects muscarinic receptors. So

it hardly surprising that it can have a positive effect on libido.

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I guess that this effect of extasy is just short term? If extasy can

diminish PSSD symptoms can be much better evaluated if this experiment

is repeated ten or twenty times.

There is a risk that extacy is polluted with unhealthy ingredients,

since its production is not supervised by the authorities.

>

> I found that extacy improved all of these problems and I could get

> normal feeling erections again. In fact, this kicked in just at the

end of the mid week blues, and lasted a few days.

>

> I don't know what caused this, but I expect it was something to do with

> specific serotonin disorders. Alternatively, it could have been

> somethig entirely unconnected such as change in sleep etc.

>

> However, I also had a similar experience another time, on the night

> when I was taking extacy. I thnk MDMA mainly enhances 5ht2 and 5ht1a

> receptors. It also raises oxytocin levels, has an effect on dopamine,

> raises nitric oxide synthase, and also effects muscarinic receptors. So

> it hardly surprising that it can have a positive effect on libido.

>

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No, no and no.

We should not be taking MDMA in regular experikments because it is

toxic.

The libido effects seemed to last for up to 7 days after the first

time of use.

Pure MDMA is very rarely mixed with other substances, but the price is

put up instead.

>

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  • 3 weeks later...
Guest guest

I'm well aware of what penile anaethesia is. My glans (before

sensitive)feels like any other normal skin on my body. I cant even

feel my frenulum (most sensitive part of the penis) its as if all

the nerve endings in penis are gone. I cant even feel pain there as

I did before. The sensivity also fluctuates, for example, some days

it better than others. I did full blood work from urologists,

everything was normal. I even did a bulborous reflex test with an

electrical current. (Usually done for people suffering from

neuropathy), again normal. My full sensitivity came back for 2-3

days in September. Did nothing special for that to happen.

My two questions are 1) Any men having sex here who have this

problem? How does it feel and how do you cope with this? 2)Women are

10 X more likely than men to take antidepressants, how come we dont

see an equal if not more number of women on this forum.

> > > >

> > > > Have you had your testosterone levels checked? Mine are a bit

> low and

> > > > I have this problem. My understanding is that low

testosterone can

> > > > cause this.

> > > >

> > > > ~

> > > >

> > >

> >

>

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It is not because the nerve endings are " gone. " Ive found that using

nutmeg/MDMA/cannibis somewhat lessens this problem. It is probably

mainly to do with specific serotonin neurons, dopamine, and nitric

oxide. It is not nerve dmaage as some people have previously insinuated.

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  • 2 months later...
Guest guest

Dear pssd24

I have heard from a few people who have taken extacy that it has

improved their sex drive and sensitivity in ways not felt prior so i

have always been curious about it but never considered using it

often. After reading were you said that it stopped your pssd

completely for a while after using it and that it was the real

thing, that curiousity went WAY up. But then it went down after I

read where you said that marijunia and alchohol had similar effects.

A lot of my family uses marijunia so I use it every now and then to

be sociable but I really dont consider it worth more than that or

worth forking out all the money for but it does relax you. I also am

a social drinker. Neither one, by itself or in comination, has never

increased my libido or orgasm in any noticeably significant way.

Also most of what I have heard or read is that marijunia and

alchohol, by theirselves or in combonation, if used excesively, can

cause sexual dysfunction just like antidepressants. So my hopes went

down after i read where it said that you got similar effects from

weed, alchohol, nutmeg, etc. So I would really like to know if you

are just getting peoples hopes up by advertising street drugs or are

you really getting real results, better than the rest of us, and can

you describe the differences between each? Thank you.

Also to sssssssri. Sorry for not writing back after a couple of

weeks. I've either been very busy with something or very depressed.

But to answer your question - I dont know if the USA or what other

countries have discontinued nefazodone, I was actually just talking

about my hospital's pharmacy system.

Also, to those who said that they've experienced suicidal thoughts -

I must admit that I have had them at times. My hats off to you if

it has never crossed your mind. But trying to stay strong and having

good distractions and having hope that something can give is how I

cope.

>

> I only took a little bit of nutmeg. Overall cannibis seems to be

> better, to my surprise.

>

> Cannibis mainly acts on the 5ht1a receptors. It improves orgasm

pretty

> quickly, and also makes you much more interested in sex. It blocks

> dopamine as well, which I suppose could cause dopamine to

stockpile?

> But in my experience, pssd is possibly cause by problems with

specific

> receptors, and not just " low dopamine. " I have seen many dopamine

meds

> tried, and none of them really work for long.

>

> The nutmeg seemed to work better for a few days after drinking

alcahol.

> However, cannibis tea still comes over as much better. Its

possible

> that a combination of the two would have much better effects.

>

> One interesting side effect of nutmeg, which I had expected, was

that

> it caused my dreams to return completely. This is probably due to

> activation of the 5ht2a receptors.

>

> To my surprise, cannibis also caused enhanced REM sleep (possiboy

sue

> to dopamine or canaboid rectors?). Enhancement of the 5ht1a

receptors

> should really block REM sleep.

>

> The other thing that seems to improve libido and softens the penis

is

> the comedown from alcahol, which acts on serotonin, gaba and

dopamine.

> I do not know whether it acts oin specific receptors or not.

Serotonin

> is very specific and some of the recptors heighten libido, whilst

> others weaken it.

>

> However, i will not give up this line of enquiry at present. I

have had

> some interesting results. More interesting overall than with

muccuna

> puriens or bupropion alone. Certainly cannibis is pretty effective

at

> alleviating the depression and loss of libido caused by pssd,

> particularly when taken as a tea and not taken too much.

>

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I've always been curious about MDMA. And i've been really curious

about trying it but I've been afraid because of it's action on

serotonin receptors, I am weary if it would make my condition worse.

But, I am looking to have a dramatic, epiphanic experience. I've got

nothing to lose at this point. Also it is a very therapeutic drug, and

it could make things better in the long run. I've been looking into

things like mushrooms as well. I need something as a guiding force -

too bring things into a different perspective.

> >

> > I only took a little bit of nutmeg. Overall cannibis seems to be

> > better, to my surprise.

> >

> > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm

> pretty

> > quickly, and also makes you much more interested in sex. It blocks

> > dopamine as well, which I suppose could cause dopamine to

> stockpile?

> > But in my experience, pssd is possibly cause by problems with

> specific

> > receptors, and not just " low dopamine. " I have seen many dopamine

> meds

> > tried, and none of them really work for long.

> >

> > The nutmeg seemed to work better for a few days after drinking

> alcahol.

> > However, cannibis tea still comes over as much better. Its

> possible

> > that a combination of the two would have much better effects.

> >

> > One interesting side effect of nutmeg, which I had expected, was

> that

> > it caused my dreams to return completely. This is probably due to

> > activation of the 5ht2a receptors.

> >

> > To my surprise, cannibis also caused enhanced REM sleep (possiboy

> sue

> > to dopamine or canaboid rectors?). Enhancement of the 5ht1a

> receptors

> > should really block REM sleep.

> >

> > The other thing that seems to improve libido and softens the penis

> is

> > the comedown from alcahol, which acts on serotonin, gaba and

> dopamine.

> > I do not know whether it acts oin specific receptors or not.

> Serotonin

> > is very specific and some of the recptors heighten libido, whilst

> > others weaken it.

> >

> > However, i will not give up this line of enquiry at present. I

> have had

> > some interesting results. More interesting overall than with

> muccuna

> > puriens or bupropion alone. Certainly cannibis is pretty effective

> at

> > alleviating the depression and loss of libido caused by pssd,

> > particularly when taken as a tea and not taken too much.

> >

>

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You misunderstood. The main point I made was that cannibis helped me

to sleep and made me feel more awake.

MDMA increases vasporessin and oxytocin, which in turn makes more DHT

and Prostaglandin. I have suggested several times that this

completely stops pssd.

> >

> > I only took a little bit of nutmeg. Overall cannibis seems to be

> > better, to my surprise.

> >

> > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm

> pretty

> > quickly, and also makes you much more interested in sex. It

blocks

> > dopamine as well, which I suppose could cause dopamine to

> stockpile?

> > But in my experience, pssd is possibly cause by problems with

> specific

> > receptors, and not just " low dopamine. " I have seen many dopamine

> meds

> > tried, and none of them really work for long.

> >

> > The nutmeg seemed to work better for a few days after drinking

> alcahol.

> > However, cannibis tea still comes over as much better. Its

> possible

> > that a combination of the two would have much better effects.

> >

> > One interesting side effect of nutmeg, which I had expected, was

> that

> > it caused my dreams to return completely. This is probably due to

> > activation of the 5ht2a receptors.

> >

> > To my surprise, cannibis also caused enhanced REM sleep (possiboy

> sue

> > to dopamine or canaboid rectors?). Enhancement of the 5ht1a

> receptors

> > should really block REM sleep.

> >

> > The other thing that seems to improve libido and softens the

penis

> is

> > the comedown from alcahol, which acts on serotonin, gaba and

> dopamine.

> > I do not know whether it acts oin specific receptors or not.

> Serotonin

> > is very specific and some of the recptors heighten libido, whilst

> > others weaken it.

> >

> > However, i will not give up this line of enquiry at present. I

> have had

> > some interesting results. More interesting overall than with

> muccuna

> > puriens or bupropion alone. Certainly cannibis is pretty

effective

> at

> > alleviating the depression and loss of libido caused by pssd,

> > particularly when taken as a tea and not taken too much.

> >

>

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Guest guest

MDMA is quite neurotoxic, but this can be countered to a degree with

high doses of various antioxidants (see erowid mdma faqs'). However, I

still do not recommend it - I felt unwell for some time after trying

it a few years ago...

> > >

> > > I only took a little bit of nutmeg. Overall cannibis seems to be

> > > better, to my surprise.

> > >

> > > Cannibis mainly acts on the 5ht1a receptors. It improves orgasm

> > pretty

> > > quickly, and also makes you much more interested in sex. It

> blocks

> > > dopamine as well, which I suppose could cause dopamine to

> > stockpile?

> > > But in my experience, pssd is possibly cause by problems with

> > specific

> > > receptors, and not just " low dopamine. " I have seen many dopamine

> > meds

> > > tried, and none of them really work for long.

> > >

> > > The nutmeg seemed to work better for a few days after drinking

> > alcahol.

> > > However, cannibis tea still comes over as much better. Its

> > possible

> > > that a combination of the two would have much better effects.

> > >

> > > One interesting side effect of nutmeg, which I had expected, was

> > that

> > > it caused my dreams to return completely. This is probably due to

> > > activation of the 5ht2a receptors.

> > >

> > > To my surprise, cannibis also caused enhanced REM sleep (possiboy

> > sue

> > > to dopamine or canaboid rectors?). Enhancement of the 5ht1a

> > receptors

> > > should really block REM sleep.

> > >

> > > The other thing that seems to improve libido and softens the

> penis

> > is

> > > the comedown from alcahol, which acts on serotonin, gaba and

> > dopamine.

> > > I do not know whether it acts oin specific receptors or not.

> > Serotonin

> > > is very specific and some of the recptors heighten libido, whilst

> > > others weaken it.

> > >

> > > However, i will not give up this line of enquiry at present. I

> > have had

> > > some interesting results. More interesting overall than with

> > muccuna

> > > puriens or bupropion alone. Certainly cannibis is pretty

> effective

> > at

> > > alleviating the depression and loss of libido caused by pssd,

> > > particularly when taken as a tea and not taken too much.

> > >

> >

>

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> > >

> > > I only took a little bit of nutmeg. Overall cannibis seems to

be

> > > better, to my surprise.

> > >

> > > Cannibis mainly acts on the 5ht1a receptors. It improves

orgasm

> > pretty

> > > quickly, and also makes you much more interested in sex. It

> blocks

> > > dopamine as well, which I suppose could cause dopamine to

> > stockpile?

> > > But in my experience, pssd is possibly cause by problems with

> > specific

> > > receptors, and not just " low dopamine. " I have seen many

dopamine

> > meds

> > > tried, and none of them really work for long.

> > >

> > > The nutmeg seemed to work better for a few days after drinking

> > alcahol.

> > > However, cannibis tea still comes over as much better. Its

> > possible

> > > that a combination of the two would have much better effects.

> > >

> > > One interesting side effect of nutmeg, which I had expected,

was

> > that

> > > it caused my dreams to return completely. This is probably due

to

> > > activation of the 5ht2a receptors.

> > >

> > > To my surprise, cannibis also caused enhanced REM sleep

(possiboy

> > sue

> > > to dopamine or canaboid rectors?). Enhancement of the 5ht1a

> > receptors

> > > should really block REM sleep.

> > >

> > > The other thing that seems to improve libido and softens the

> penis

> > is

> > > the comedown from alcahol, which acts on serotonin, gaba and

> > dopamine.

> > > I do not know whether it acts oin specific receptors or not.

> > Serotonin

> > > is very specific and some of the recptors heighten libido,

whilst

> > > others weaken it.

> > >

> > > However, i will not give up this line of enquiry at present. I

> > have had

> > > some interesting results. More interesting overall than with

> > muccuna

> > > puriens or bupropion alone. Certainly cannibis is pretty

> effective

> > at

> > > alleviating the depression and loss of libido caused by pssd,

> > > particularly when taken as a tea and not taken too much.

> > >

> >

>

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