Re: Clomid study for Hypogonadism

[Guest guest]

would taking this only resolve the problem of low t levels while your

on the drug and not after you stop taking it?

or is it the case that the increase will fade away after you

discontinue the drug?

>

> I am posting this for informational purposes. Hopefully it will help

> others with this condition. Many folks on the list have had blood

work

> done.

> The general definition of hypogonadism is 300ng/dl, but age is also

a

> consideration (it should be). If your 20 or 30 y.o., you should

have a

> T level of about 800ng/dl. Here is the treatment study I found.

> Maybe it would be a good idea to print this study so your doctor

won't

> be a total dumb @ss..

>

>

> Clomid study, notice the dose used just 25mg/day:

>

>

> Clomiphene Citrate Effects on Testosterone/Estrogen Ratio in Male

> Hypogonadism

> J Sex Med 2005;2:716–721.

>

> ABSTRACT

>

> Aim. Symptomatic late-onset hypogonadism is associated not only

with a

> decline in serum testosterone, but also with a rise in serum

> estradiol. These endocrine changes negatively affect libido, sexual

> function, mood, behavior, lean body mass, and bone density.

Currently,

> the most common treatment is exogenous testostosterone therapy. This

> treatment can be associated with skin irritation, gynecomastia,

nipple

> tenderness, testicular atrophy, and decline in sperm counts. In this

> study we investigated the efficacy of clomiphene citrate in the

> treatment of hypogonadism with the objectives of raising endogenous

> serum testosterone (T) and improving the testosterone/estrogen (T/E)

> ratio.

>

> Methods. Our cohort consisted of 36 Caucasian men with hypogonadism

> defined as serum testosterone level less than 300 ng/dL. Each

patient

> was treated with a daily dose of 25 mg clomiphene citrate and

followed

> prospectively. Analysis of baseline and follow-up serum levels of

> testosterone and estradiol levels were performed.

>

> Results. The mean age was 39 years, and the mean pretreatment

> testosterone and estrogen levels were 247.6 ± 39.8 ng/dL and 32.3 ±

> 10.9, respectively. By the first follow-up visit (4–6 weeks),

> the mean testosterone level rose to 610.0 ± 178.6 ng/dL (P <

0.00001).

> Moreover, the T/E ratio improved from 8.7 to 14.2 (P < 0.001). There

> were no side effects reported by the patients.

>

> Conclusions. Low dose clomiphene citrate is effective in elevating

> serum testosterone levels and improving the testosterone/estadiol

> ratio in men with hypogonadism. This therapy represents an

alternative

> to testosterone therapy by stimulating the endogenous androgen

> production pathway.

> __________________

>

[Guest guest]

1. It will increase T level while you take it.

2. After you stop taking it, the incresed T level will continue for

some time.

3. I don't know if you'll eventually go back to being hypo.

I took some clomid sometime in 2006. I had blood tests done. My T

level was elevated higher than normal for several weeks after

discontinuation. About a month later (don't remember exact time frame)

the T level was back to " normal " .

Because my doctor and the endo didn't like what I was doing, they told

me not to take anymore and didn't follow up with more tests.What they

advised wasn't based on science, and they didn't offer any help for a

solution. But the point of this story is that the elevated T levels

can last for months after discontinuation. You will have to get your

own blood testing done to find your own levels. Also, don't take to

much, it will make your vision blurry and trippy.

> >

> > I am posting this for informational purposes. Hopefully it will help

> > others with this condition. Many folks on the list have had blood

> work

> > done.

> > The general definition of hypogonadism is 300ng/dl, but age is also

> a

> > consideration (it should be). If your 20 or 30 y.o., you should

> have a

> > T level of about 800ng/dl. Here is the treatment study I found.

> > Maybe it would be a good idea to print this study so your doctor

> won't

> > be a total dumb @ss..

> >

> >

> > Clomid study, notice the dose used just 25mg/day:

> >

> >

> > Clomiphene Citrate Effects on Testosterone/Estrogen Ratio in Male

> > Hypogonadism

> > J Sex Med 2005;2:716–721.

> >

> > ABSTRACT

> >

> > Aim. Symptomatic late-onset hypogonadism is associated not only

> with a

> > decline in serum testosterone, but also with a rise in serum

> > estradiol. These endocrine changes negatively affect libido, sexual

> > function, mood, behavior, lean body mass, and bone density.

> Currently,

> > the most common treatment is exogenous testostosterone therapy. This

> > treatment can be associated with skin irritation, gynecomastia,

> nipple

> > tenderness, testicular atrophy, and decline in sperm counts. In this

> > study we investigated the efficacy of clomiphene citrate in the

> > treatment of hypogonadism with the objectives of raising endogenous

> > serum testosterone (T) and improving the testosterone/estrogen (T/E)

> > ratio.

> >

> > Methods. Our cohort consisted of 36 Caucasian men with hypogonadism

> > defined as serum testosterone level less than 300 ng/dL. Each

> patient

> > was treated with a daily dose of 25 mg clomiphene citrate and

> followed

> > prospectively. Analysis of baseline and follow-up serum levels of

> > testosterone and estradiol levels were performed.

> >

> > Results. The mean age was 39 years, and the mean pretreatment

> > testosterone and estrogen levels were 247.6 ± 39.8 ng/dL and 32.3 ±

> > 10.9, respectively. By the first follow-up visit (4–6 weeks),

> > the mean testosterone level rose to 610.0 ± 178.6 ng/dL (P <

> 0.00001).

> > Moreover, the T/E ratio improved from 8.7 to 14.2 (P < 0.001). There

> > were no side effects reported by the patients.

> >

> > Conclusions. Low dose clomiphene citrate is effective in elevating

> > serum testosterone levels and improving the testosterone/estadiol

> > ratio in men with hypogonadism. This therapy represents an

> alternative

> > to testosterone therapy by stimulating the endogenous androgen

> > production pathway.

> > __________________

> >

>

[Guest guest]

im gonna try the zinc first see where that gets me, then ill look

into other things.

im waiting for this zinc taste test that ive ordered.

> > >

> > > I am posting this for informational purposes. Hopefully it will

help

> > > others with this condition. Many folks on the list have had

blood

> > work

> > > done.

> > > The general definition of hypogonadism is 300ng/dl, but age is

also

> > a

> > > consideration (it should be). If your 20 or 30 y.o., you should

> > have a

> > > T level of about 800ng/dl. Here is the treatment study I found.

> > > Maybe it would be a good idea to print this study so your

doctor

> > won't

> > > be a total dumb @ss..

> > >

> > >

> > > Clomid study, notice the dose used just 25mg/day:

> > >

> > >

> > > Clomiphene Citrate Effects on Testosterone/Estrogen Ratio in

Male

> > > Hypogonadism

> > > J Sex Med 2005;2:716–721.

> > >

> > > ABSTRACT

> > >

> > > Aim. Symptomatic late-onset hypogonadism is associated not only

> > with a

> > > decline in serum testosterone, but also with a rise in serum

> > > estradiol. These endocrine changes negatively affect libido,

sexual

> > > function, mood, behavior, lean body mass, and bone density.

> > Currently,

> > > the most common treatment is exogenous testostosterone therapy.

This

> > > treatment can be associated with skin irritation, gynecomastia,

> > nipple

> > > tenderness, testicular atrophy, and decline in sperm counts. In

this

> > > study we investigated the efficacy of clomiphene citrate in the

> > > treatment of hypogonadism with the objectives of raising

endogenous

> > > serum testosterone (T) and improving the testosterone/estrogen

(T/E)

> > > ratio.

> > >

> > > Methods. Our cohort consisted of 36 Caucasian men with

hypogonadism

> > > defined as serum testosterone level less than 300 ng/dL. Each

> > patient

> > > was treated with a daily dose of 25 mg clomiphene citrate and

> > followed

> > > prospectively. Analysis of baseline and follow-up serum levels

of

> > > testosterone and estradiol levels were performed.

> > >

> > > Results. The mean age was 39 years, and the mean pretreatment

> > > testosterone and estrogen levels were 247.6 ± 39.8 ng/dL and

32.3 ±

> > > 10.9, respectively. By the first follow-up visit (4–6

weeks),

> > > the mean testosterone level rose to 610.0 ± 178.6 ng/dL (P <

> > 0.00001).

> > > Moreover, the T/E ratio improved from 8.7 to 14.2 (P < 0.001).

There

> > > were no side effects reported by the patients.

> > >

> > > Conclusions. Low dose clomiphene citrate is effective in

elevating

> > > serum testosterone levels and improving the

testosterone/estadiol

> > > ratio in men with hypogonadism. This therapy represents an

> > alternative

> > > to testosterone therapy by stimulating the endogenous androgen

> > > production pathway.

> > > __________________

> > >

> >

>