Re: Environmental risk factors differ between rheumatoid arthrit...

[Guest guest]

can someone explain this to me... in plain english. lol thanks

[Guest guest]

, here goes ...

Whether a person develops rheumatoid arthritis is thought to be dependent on

several factors and not necessarily the same reasons for all people.

It is believed that there is a genetic susceptibility and also environmental

factors. We don't know all of the genes involved. We don't know with great

certainly about the environmental variables either.

In this study, they looked at 515 people who had could be classified as

having RA (according the ACR criteria for classification of RA) and 769

people without RA (the control subjects). They wanted to see if there was a

difference between the anti-CCP-positive and anti-CCP-negative patients in

terms of environmental exposure.

Smoking was associated with anti-CCP-positive RA. Drinking was inversely

associated with anti-CCP-positive RA (people with RA were less likely to be

anti-CCP-positive if they drank). Drinking coffee, ever having used oral

contraceptives, and having a first-degree relative with schizophrenia were

also risk factors for having anti-CCP-positive RA. Obesity was associated

with anti-CCP-negative RA. For women who first menstruated at age 15 or

greater, the risk of having either anti-CCP-negative or positive RA was

about twice that of individuals who reached menarche at age 12 or earlier.

Original article:

http://arthritis-research.com/content/8/4/R133

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

Re: [ ] Environmental risk factors differ between

rheumatoid arthrit...

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> can someone explain this to me... in plain english. lol thanks