Wellbutrin?

[Guest guest]

I am curious about your (the entire group) experiences with Wellbutrin

(Bupropion Hcl).

Are there any of you who have ONLY taken Wellbutrin (no other

antidepressant class medication) or were taking it most recently -

that is, just prior to PSSD?

Have any of you taken Wellbutrin in treatment for PSSD? If so, what

have been your experiences? Has it helped? If so, for how long? Does

it still? Did you later discontinue it? If so, why?

(Before someone attacks me for asking a " dumb " or " irrelevant "

question, I DO realize bupropion is not strictly speaking an SSRI and

as such has a somewhat different mechanism of action - mainly acting

on dopamine and norepinephrine [though it has been shown that its

metabolites do appear to act on serotonin circuitry as well]. I also

realize that this fact would seem to exclude it from the domain: " Post

SSRI Sexual Disfunction " . Nevertheless, I am very curious about

others' experiences with this drug. Before discontinuing all

medications over a year ago, I was most recently taking Wellbutrin XL

(300mg) to ameliorate the sexual side-effects of Effexor XR (75mg) and

citalopram (20mg) in turn. Initially, immediately, and with

overwhelming success, it restored: orgasm quality; erectile function,

rigidity, and spontaneity; and a healthy libido to levels I recall

experiencing as a teenager prior to any antidepressant therapy. Then -

suddenly and to my great disappointment - that effect disappeared

after a several months of daily use. As it is likely my body's

dopamine circuitry re-regulated itself (down-regulating receptors

and/or DA/NE production) to accommodate the increase in DA/NE

availability from re-uptake inhibition, I consider Wellbutrin (an NDRI

not SSRI) a possible culprit in my current condition or at least a

contributing factor.)

Any thoughts?