Re: question for the group

[Guest guest]

hello

i also wonder about this. whilst i was on paxil i was advised by my

doctor to take the occassional 'drug holiday' i.e. miss a dose in

order to bypass the sexual side-effects somewhat and have a fairly

pleasurable sexual experience with my partner. i did this right up

until i quit the drug and experienced only an occasional problem with

erections and numbness and always had a good orgasm. now i have

problems with all of these things and it is the lack of pleasure

associated with orgasm that worries me the most. but my point is that

i could and would experience very good orgasms when i occasionally

missed a dose and right up until i quit the drug, so i feel sure that

the speed at which i quit it (a few weeks) must have something to do

with it. how come i was able to experience a great orgasm one day and

then literally feel nothing a few days later and ever since. i have

also wondered about whether or not restarting and reducing the dose

more slowly might help, but the prospect of doing so scares me to

death for a number of reasons. firstly, the last year that i was

taking it i suffered from extreme suicidal ideation which i did not

realise the drug was directly responsible for and do not want to go

back to that. and secondly, i have been off for 15 months now and it

has felt like 15 years and although i have seen little progress what

if going back on an ssri makes things worse or hinders any progress

that time may be making? there is a guy on this forum that takes a

small dose of prozac in combination with something else and states

that it has helped his pssd, but what will happen when he stops

taking these drugs?

>

> Has anyone ever had PSSD and later gone back on SSRIs? Did you

notice

> any changes? If you later discontinued the medication [again] did

your

> sexual symptoms persist as before?

>

> I ask because some people have theorized that PSSD results when

people

> discontinue their medication suddenly rather than by a gradual

> decrease in dosage. If this is indeed a factor, or if these drugs do

> in fact cause neurogenomic changes that down-/up-regulate receptor

> expression, it might be possible to catalyze positive changes in

> sexual function/sensitivity by re-medicating for a period of time

and

> then slowly tapering the dose to discontinue.

>

> Personally, my side-effect profile and treatment response has varied

> between separate treatment courses with the same medication (ie.

> effexor during 1999, and effexor during 2005-2007) - so perhaps it

is

> possible to reverse PSSD symptoms by trying another season of

> medication followed by controlled discontinuation?

>

> Just a thought...any comments, ideas?

>

[Guest guest]

I was on nefazodone for 3 months which didn't effect my sex drive at

all and then in one week it completely went. I came off the drug,

cold turkey - but I was on the lowest dose anyway - and within days

my sex drive went sky high. It was absolutely mind bending and quite

disturbing. I then went back on the drug because the withdrawals were

so bad but I cut the dose down to half a tablet a day. A week later I

went to a 1/4 of a tablet and then I cut it in half again and so on.

After a month I was on a very small dose and I was just about to stop

taking it when my sex drive went again never to return. Coming off

the drug made no difference. I had twitching that went on for two

years but that finally went so it looks like the brain can heal in

some ways. So I hang on to hope.

I should have never restarted the drug but I had no idea that I would

suffer permanent damage. We all takes pills and medicine all our

lives - cough mixture, asprin, etc - so why should I suspect that

something the doctor prescribes could do so much damage? I had taken

their medicines before.

In all the magazines and newspapers I had read that antidepressants

were considered safe. I even read that cortisol, the stress chemical,

damages the brain and that antidepressants stop this so it's best to

take one. But it's all marketing sales pitch rubbish.

Kavy

I

> >

> > Has anyone ever had PSSD and later gone back on SSRIs? Did you

> notice

> > any changes? If you later discontinued the medication [again] did

> your

> > sexual symptoms persist as before?

> >

> > I ask because some people have theorized that PSSD results when

> people

> > discontinue their medication suddenly rather than by a gradual

> > decrease in dosage. If this is indeed a factor, or if these drugs

do

> > in fact cause neurogenomic changes that down-/up-regulate receptor

> > expression, it might be possible to catalyze positive changes in

> > sexual function/sensitivity by re-medicating for a period of time

> and

> > then slowly tapering the dose to discontinue.

> >

> > Personally, my side-effect profile and treatment response has

varied

> > between separate treatment courses with the same medication (ie.

> > effexor during 1999, and effexor during 2005-2007) - so perhaps

it

> is

> > possible to reverse PSSD symptoms by trying another season of

> > medication followed by controlled discontinuation?

> >

> > Just a thought...any comments, ideas?

> >

>

[Guest guest]

I have twice used SSRIs again. Both times, I weaned off slowly. Both

times, my sex drive and erection quality have taken a permanent

ADDITIONAL plunge. So at least based on my experience, I would very

strongly advise against taking SSRIs (again).

Hope this helps.

teephos

>

> Has anyone ever had PSSD and later gone back on SSRIs? Did you notice

> any changes? If you later discontinued the medication [again] did your

> sexual symptoms persist as before?

>

> I ask because some people have theorized that PSSD results when people

> discontinue their medication suddenly rather than by a gradual

> decrease in dosage. If this is indeed a factor, or if these drugs do

> in fact cause neurogenomic changes that down-/up-regulate receptor

> expression, it might be possible to catalyze positive changes in

> sexual function/sensitivity by re-medicating for a period of time and

> then slowly tapering the dose to discontinue.

>

> Personally, my side-effect profile and treatment response has varied

> between separate treatment courses with the same medication (ie.

> effexor during 1999, and effexor during 2005-2007) - so perhaps it is

> possible to reverse PSSD symptoms by trying another season of

> medication followed by controlled discontinuation?

>

> Just a thought...any comments, ideas?

>

[Guest guest]

And you had suffered from PSSD before you used SSRI again ?To: SSRIsex Sent: Friday, December 12, 2008 8:47:11 PMSubject: Re: question for the group

I have twice used SSRIs again. Both times, I weaned off slowly. Both

times, my sex drive and erection quality have taken a permanent

ADDITIONAL plunge. So at least based on my experience, I would very

strongly advise against taking SSRIs (again).

Hope this helps.

teephos

>

> Has anyone ever had PSSD and later gone back on SSRIs? Did you notice

> any changes? If you later discontinued the medication [again] did your

> sexual symptoms persist as before?

>

> I ask because some people have theorized that PSSD results when people

> discontinue their medication suddenly rather than by a gradual

> decrease in dosage. If this is indeed a factor, or if these drugs do

> in fact cause neurogenomic changes that down-/up-regulate receptor

> expression, it might be possible to catalyze positive changes in

> sexual function/sensitivit y by re-medicating for a period of time and

> then slowly tapering the dose to discontinue.

>

> Personally, my side-effect profile and treatment response has varied

> between separate treatment courses with the same medication (ie.

> effexor during 1999, and effexor during 2005-2007) - so perhaps it is

> possible to reverse PSSD symptoms by trying another season of

> medication followed by controlled discontinuation?

>

> Just a thought...any comments, ideas?

>

[Guest guest]

Yes. It made PSSD worse.

> >

> > Has anyone ever had PSSD and later gone back on SSRIs? Did you notice

> > any changes? If you later discontinued the medication [again] did your

> > sexual symptoms persist as before?

> >

> > I ask because some people have theorized that PSSD results when people

> > discontinue their medication suddenly rather than by a gradual

> > decrease in dosage. If this is indeed a factor, or if these drugs do

> > in fact cause neurogenomic changes that down-/up-regulate receptor

> > expression, it might be possible to catalyze positive changes in

> > sexual function/sensitivit y by re-medicating for a period of time and

> > then slowly tapering the dose to discontinue.

> >

> > Personally, my side-effect profile and treatment response has varied

> > between separate treatment courses with the same medication (ie.

> > effexor during 1999, and effexor during 2005-2007) - so perhaps it is

> > possible to reverse PSSD symptoms by trying another season of

> > medication followed by controlled discontinuation?

> >

> > Just a thought...any comments, ideas?

> >

>