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Hello

Can anybody please tell me why I am suddenly experiencing the most terrible

mood swings?

It is crazy, I can't believe this is me. I used to be the most stable person,

always able to control myself, very constant. But what is happening now is

really scary!!

Though I have Lupus and Sclerosis (2 years), my condition is more or less

stable, I don't think that I am really suffering horribly. I think they are

overlapping, so I have no really clear symptoms of either.

I am on methotrexate, depomedrol and plaquenil.

There is no really 'big' problem in my life, just the usual, so no reason from

this direction. Is it the medication?

Any experts out there?

I really don't want to take any anit-depressants, any alternative?

Thanks and have a nice day

amira

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One of the first things that comes to mind is " how old are you " ?...

Anytime someone mentions severe, out of the blue mood swings, I think

menopause.

If you have lupus, even if your YOUNG, you could be going through

" premature ovarian failure " . Lupus doesn't just eat your muscles,

kidneys and other tender bits, auto immunity can cause thyroid failure,

type 1 diabetes and early infertility.

The second thing is have you had a CBC [ complete blood count] done

recently? You might have one of the more virulent forms of anemia.

Especially taking methotrexate. It can leave you with megoblastic

anemia, and since the B-vitamins control nerve function..you won't just

be tired.

There is also " Depression of chronic illness " which is very common in

auto immune disorders. Not all depressed people are " blue " or " down " ,

sometimes depression can manifest as agitation and anxiety.

< sheepish grin>

Hope this helps

Ms.

IVRDSG@...

Amira Ramy wrote:

> Hello

>

> Can anybody please tell me why I am suddenly experiencing the most

> terrible mood swings?

> It is crazy, I can't believe this is me. I used to be the most stable

> person, always able to control myself, very constant. But what is

> happening now is really scary!!

>

> Though I have Lupus and Sclerosis (2 years), my condition is more or

> less stable, I don't think that I am really suffering horribly. I

> think they are overlapping, so I have no really clear symptoms of either.

>

> I am on methotrexate, depomedrol and plaquenil.

>

> There is no really 'big' problem in my life, just the usual, so no

> reason from this direction. Is it the medication?

>

> Any experts out there?

>

> I really don't want to take any anit-depressants, any alternative?

>

> Thanks and have a nice day

> amira

>

>

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Guest guest

Amira,

The Depo-Medrol is a strong suspect, since corticosteroids often

cause mood swings. How long have you been on it?

How long have you been on MTX and Plaquenil, and when did the mood

swings start?

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

>

> Hello

>

> Can anybody please tell me why I am suddenly experiencing the

most terrible mood swings?

> It is crazy, I can't believe this is me. I used to be the most

stable person, always able to control myself, very constant. But what

is happening now is really scary!!

>

> Though I have Lupus and Sclerosis (2 years), my condition is more

or less stable, I don't think that I am really suffering horribly. I

think they are overlapping, so I have no really clear symptoms of

either.

>

> I am on methotrexate, depomedrol and plaquenil.

>

> There is no really 'big' problem in my life, just the usual, so

no reason from this direction. Is it the medication?

>

> Any experts out there?

>

> I really don't want to take any anit-depressants, any alternative?

>

> Thanks and have a nice day

> amira

>

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Guest guest

Hi Amira. I'm in no way an expert and still pretty new at dealing

with this myself, but personally, my moods drop suddenly just from

sheer frustration. Trying to get meds regulated, dealing with

secondary infections, extreme fatigue, etc. Everyone here is so

supportive, that's why I keep coming back. Even if I don't post

alot, it's encouraging to know that there are others out there, and

they are survivors!

Blessings,

>

> Hello

>

> Can anybody please tell me why I am suddenly experiencing the

most terrible mood swings?

> It is crazy, I can't believe this is me. I used to be the most

stable person, always able to control myself, very constant. But what

is happening now is really scary!!

>

> Though I have Lupus and Sclerosis (2 years), my condition is more

or less stable, I don't think that I am really suffering horribly. I

think they are overlapping, so I have no really clear symptoms of

either.

>

> I am on methotrexate, depomedrol and plaquenil.

>

> There is no really 'big' problem in my life, just the usual, so

no reason from this direction. Is it the medication?

>

> Any experts out there?

>

> I really don't want to take any anit-depressants, any alternative?

>

> Thanks and have a nice day

> amira

>

>

>

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Guest guest

Has anyone got depression on the AP? I have and I know that's what it is because

never had it in my 14 yrs w/ the RA. Yes, tha's right, I got down when I first

got diagnosed, but not what I feel now, no specific reasons that would trigger

anything. I am thinking about stopping the AP for awhile, so I can get myself

back to normal. Thanks,

eandsspivey <espivey@...> wrote: Hi Amira. I'm in no way an

expert and still pretty new at dealing

with this myself, but personally, my moods drop suddenly just from

sheer frustration. Trying to get meds regulated, dealing with

secondary infections, extreme fatigue, etc. Everyone here is so

supportive, that's why I keep coming back. Even if I don't post

alot, it's encouraging to know that there are others out there, and

they are survivors!

Blessings,

>

> Hello

>

> Can anybody please tell me why I am suddenly experiencing the

most terrible mood swings?

> It is crazy, I can't believe this is me. I used to be the most

stable person, always able to control myself, very constant. But what

is happening now is really scary!!

>

> Though I have Lupus and Sclerosis (2 years), my condition is more

or less stable, I don't think that I am really suffering horribly. I

think they are overlapping, so I have no really clear symptoms of

either.

>

> I am on methotrexate, depomedrol and plaquenil.

>

> There is no really 'big' problem in my life, just the usual, so

no reason from this direction. Is it the medication?

>

> Any experts out there?

>

> I really don't want to take any anit-depressants, any alternative?

>

> Thanks and have a nice day

> amira

>

>

>

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Guest guest

Hi Amira,

Have you had your thyroid tested lately? Hypothyroidism seems to go with RA and

can cause mood swings. It can be easily regulate with a synthetic hormone, but

if this is the case be sure to get the name brand synthroid and not a generic.

This is one case where it does make a difference.

Re: mood swings

Posted by: " eandsspivey " espivey@... eandsspivey

Date: Mon Aug 7, 2006 4:58 pm (PDT)

> Hello

>

> Can anybody please tell me why I am suddenly experiencing the

most terrible mood swings?

> It is crazy, I can't believe this is me. I used to be the most

stable person, always able to control myself, very constant. But what

is happening now is really scary!!

>

> Though I have Lupus and Sclerosis (2 years), my condition is more

or less stable, I don't think that I am really suffering horribly. I

think they are overlapping, so I have no really clear symptoms of

either.

>

> I am on methotrexate, depomedrol and plaquenil.

>

> There is no really 'big' problem in my life, just the usual, so

no reason from this direction. Is it the medication?

>

> Any experts out there?

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  • 2 weeks later...

Hey

I have been on mtx for two years, never complained of depression.

Then I was on depomedrol for 1 year, then did not need it for approx. one more

year and had to start 3 months ago. During this first year no complaints of

depression

Plaquenil was started 3 months ago, depression 2 months ago. That's why I was

suspecting the plaquenil.

However, it might be s.th. else like some of the other members suggested. But

when you have an autoimmune disease, where you have to take lots of meds., you

always attribute any new symptom to either autoimmune or the meds, though it

could be s.th. completely unrelated.

Thank you all for your replies

amira

<Matsumura_Clan@...> wrote:

Amira,

The Depo-Medrol is a strong suspect, since corticosteroids often

cause mood swings. How long have you been on it?

How long have you been on MTX and Plaquenil, and when did the mood

swings start?

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

>

> Hello

>

> Can anybody please tell me why I am suddenly experiencing the

most terrible mood swings?

> It is crazy, I can't believe this is me. I used to be the most

stable person, always able to control myself, very constant. But what

is happening now is really scary!!

>

> Though I have Lupus and Sclerosis (2 years), my condition is more

or less stable, I don't think that I am really suffering horribly. I

think they are overlapping, so I have no really clear symptoms of

either.

>

> I am on methotrexate, depomedrol and plaquenil.

>

> There is no really 'big' problem in my life, just the usual, so

no reason from this direction. Is it the medication?

>

> Any experts out there?

>

> I really don't want to take any anit-depressants, any alternative?

>

> Thanks and have a nice day

> amira

>

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Amira,

It's possible that it's the Plaquenil. All three of your meds have the

potential to affect your mood.

If you have lupus, you could have central nervous system involvement which

could be responsible for your mood changes.

When you say you have " Sclerosis, " do you mean systemic sclerosis or

multiple sclerosis?

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

Re: [ ] Re: mood swings

> Hey

>

>

> I have been on mtx for two years, never complained of depression.

> Then I was on depomedrol for 1 year, then did not need it for approx. one

> more year and had to start 3 months ago. During this first year no

> complaints of depression

>

> Plaquenil was started 3 months ago, depression 2 months ago. That's why I

> was suspecting the plaquenil.

>

> However, it might be s.th. else like some of the other members suggested.

> But when you have an autoimmune disease, where you have to take lots of

> meds., you always attribute any new symptom to either autoimmune or the

> meds, though it could be s.th. completely unrelated.

>

> Thank you all for your replies

>

> amira

>

> <Matsumura_Clan@...> wrote:

> Amira,

>

> The Depo-Medrol is a strong suspect, since corticosteroids often

> cause mood swings. How long have you been on it?

>

> How long have you been on MTX and Plaquenil, and when did the mood

> swings start?

>

>

> Not an MD

>

> I'll tell you where to go!

>

> Mayo Clinic in Rochester

> http://www.mayoclinic.org/rochester

>

> s Hopkins Medicine

> http://www.hopkinsmedicine.org

>

>

>>

>> Hello

>>

>> Can anybody please tell me why I am suddenly experiencing the

> most terrible mood swings?

>> It is crazy, I can't believe this is me. I used to be the most

> stable person, always able to control myself, very constant. But what

> is happening now is really scary!!

>>

>> Though I have Lupus and Sclerosis (2 years), my condition is more

> or less stable, I don't think that I am really suffering horribly. I

> think they are overlapping, so I have no really clear symptoms of

> either.

>>

>> I am on methotrexate, depomedrol and plaquenil.

>>

>> There is no really 'big' problem in my life, just the usual, so

> no reason from this direction. Is it the medication?

>>

>> Any experts out there?

>>

>> I really don't want to take any anit-depressants, any alternative?

>>

>> Thanks and have a nice day

>> amira

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Hey

I have systemic lupus and systemic sclerosis (sine). At the ver start of my

illnesss, I felt more like having sclerosis, because my skin was burning like

hell and I always had the feeling that it is being torn apart, in addition to

horrible fatigue and problems digesting food and low grade fever! Then I had a

very calm time of remission, followed by probably lupus symtoms, joint pain,

bone pain, muscle pain alternating, always feeling that I am coming down with a

flu, But I also must admit that until now (2 years) I have not had really

damaging symptomes. I read once that sometimes two auto-immune diseases could be

hampering each other in that none of them is really able to show fully, or at

least this is what I want to believe.

Thanks for your concern and take care

amira

<Matsumura_Clan@...> wrote:

Amira,

It's possible that it's the Plaquenil. All three of your meds have the

potential to affect your mood.

If you have lupus, you could have central nervous system involvement which

could be responsible for your mood changes.

When you say you have " Sclerosis, " do you mean systemic sclerosis or

multiple sclerosis?

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

Re: [ ] Re: mood swings

> Hey

>

>

> I have been on mtx for two years, never complained of depression.

> Then I was on depomedrol for 1 year, then did not need it for approx. one

> more year and had to start 3 months ago. During this first year no

> complaints of depression

>

> Plaquenil was started 3 months ago, depression 2 months ago. That's why I

> was suspecting the plaquenil.

>

> However, it might be s.th. else like some of the other members suggested.

> But when you have an autoimmune disease, where you have to take lots of

> meds., you always attribute any new symptom to either autoimmune or the

> meds, though it could be s.th. completely unrelated.

>

> Thank you all for your replies

>

> amira

>

> <Matsumura_Clan@...> wrote:

> Amira,

>

> The Depo-Medrol is a strong suspect, since corticosteroids often

> cause mood swings. How long have you been on it?

>

> How long have you been on MTX and Plaquenil, and when did the mood

> swings start?

>

>

> Not an MD

>

> I'll tell you where to go!

>

> Mayo Clinic in Rochester

> http://www.mayoclinic.org/rochester

>

> s Hopkins Medicine

> http://www.hopkinsmedicine.org

>

>

>>

>> Hello

>>

>> Can anybody please tell me why I am suddenly experiencing the

> most terrible mood swings?

>> It is crazy, I can't believe this is me. I used to be the most

> stable person, always able to control myself, very constant. But what

> is happening now is really scary!!

>>

>> Though I have Lupus and Sclerosis (2 years), my condition is more

> or less stable, I don't think that I am really suffering horribly. I

> think they are overlapping, so I have no really clear symptoms of

> either.

>>

>> I am on methotrexate, depomedrol and plaquenil.

>>

>> There is no really 'big' problem in my life, just the usual, so

> no reason from this direction. Is it the medication?

>>

>> Any experts out there?

>>

>> I really don't want to take any anit-depressants, any alternative?

>>

>> Thanks and have a nice day

>> amira

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