Re: SSRIs may change immune system response

[Guest guest]

Why doesn't someone try injecting oxytocin, or taking it orally? Belmar pharmacy will compound oxytocin capsules using a patented delivery system .Subject: SSRIs may change immune system responseTo: SSRIsex Date: Tuesday, July 15, 2008, 10:13 AM

http://www.biopsych iatry.com/ serotonin/ immune-system. html

This article may explain the problems with poor smooth muscle

relaxation ie innability to cry, digestive problems, post nasal drip,

sinisitus, dry eyes, blurred vision, joint and muscle pains.

When your immune system is down you don't block as many white blood

cells, which in turn destroys prostagladin E1.

The only way to get prostagladin E1 back to normal would be to create

an absolutely huge rush of oxytocin, which is what seemed to happen

with MDMA, sleep deprivation, amphetamine, exercise. At least

subjectively speaking, the "loved up feeling," was always shortly

followed by a crying spell or an erection.

[Guest guest]

Those drugs you mention certainly effect many bodily systems in

different ways. So it's impossible to know if it was because of

oxytocin based on that. I've done some research on oxytocin.

My PSSD lab rat took some and all that happened was he had to sh!t a lot.

>

> http://www.biopsychiatry.com/serotonin/immune-system.html

>

> This article may explain the problems with poor smooth muscle

> relaxation ie innability to cry, digestive problems, post nasal drip,

> sinisitus, dry eyes, blurred vision, joint and muscle pains.

>

> When your immune system is down you don't block as many white blood

> cells, which in turn destroys prostagladin E1.

>

> The only way to get prostagladin E1 back to normal would be to create

> an absolutely huge rush of oxytocin, which is what seemed to happen

> with MDMA, sleep deprivation, amphetamine, exercise. At least

> subjectively speaking, the " loved up feeling, " was always shortly

> followed by a crying spell or an erection.

>

[Guest guest]

Well, oxytocin doesn't cross the blood-brain barrier. Also, if it's taken orally, it is destroyed by the digestive tract. In order to see what it does to his brain, you'd have to inject it into his cerebrospinal fluid.Subject: Re: SSRIs may change immune system responseTo: SSRIsex Date: Tuesday, July 15, 2008, 11:50 PM

Those drugs you mention certainly effect many bodily systems in

different ways. So it's impossible to know if it was because of

oxytocin based on that. I've done some research on oxytocin.

My PSSD lab rat took some and all that happened was he had to sh!t a lot.

>

> http://www.biopsych iatry.com/ serotonin/ immune-system. html

>

> This article may explain the problems with poor smooth muscle

> relaxation ie innability to cry, digestive problems, post nasal drip,

> sinisitus, dry eyes, blurred vision, joint and muscle pains.

>

> When your immune system is down you don't block as many white blood

> cells, which in turn destroys prostagladin E1.

>

> The only way to get prostagladin E1 back to normal would be to create

> an absolutely huge rush of oxytocin, which is what seemed to happen

> with MDMA, sleep deprivation, amphetamine, exercise. At least

> subjectively speaking, the "loved up feeling," was always shortly

> followed by a crying spell or an erection.

>

[Guest guest]

I think someone may have tried it already. But it is reglulated by

several other systems 5HT, dopamine, histamine, so we could try that

also.

>

> >

>

> > http://www.biopsych iatry.com/ serotonin/ immune-system. html

>

> >

>

> > This article may explain the problems with poor smooth muscle

>

> > relaxation ie innability to cry, digestive problems, post nasal

drip,

>

> > sinisitus, dry eyes, blurred vision, joint and muscle pains.

>

> >

>

> > When your immune system is down you don't block as many white

blood

>

> > cells, which in turn destroys prostagladin E1.

>

> >

>

> > The only way to get prostagladin E1 back to normal would be to

create

>

> > an absolutely huge rush of oxytocin, which is what seemed to

happen

>

> > with MDMA, sleep deprivation, amphetamine, exercise. At least

>

> > subjectively speaking, the " loved up feeling, " was always shortly

>

> > followed by a crying spell or an erection.

>

> >

>

[Guest guest]

It feels like that is what brings on the response. I think it is

unlikely that 5HT or dopamine or nitric oxide are entirely

responsible (compare nutmeg). However, i wonder if the effects on

histamine and M1 revceptors are also relevant.

> >

> > http://www.biopsychiatry.com/serotonin/immune-system.html

> >

> > This article may explain the problems with poor smooth muscle

> > relaxation ie innability to cry, digestive problems, post nasal

drip,

> > sinisitus, dry eyes, blurred vision, joint and muscle pains.

> >

> > When your immune system is down you don't block as many white

blood

> > cells, which in turn destroys prostagladin E1.

> >

> > The only way to get prostagladin E1 back to normal would be to

create

> > an absolutely huge rush of oxytocin, which is what seemed to

happen

> > with MDMA, sleep deprivation, amphetamine, exercise. At least

> > subjectively speaking, the " loved up feeling, " was always shortly

> > followed by a crying spell or an erection.

> >

>

[Guest guest]

I had some oxytocin nasal spray that I bought from a lab.

All it does is induce a trip to the bathroom.

Injecting it or taking oral doses wouldn't make any difference.

>

> Subject: SSRIs may change immune system response

> To: SSRIsex

> Date: Tuesday, July 15, 2008, 10:13 AM

>

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>

> http://www.biopsych iatry.com/ serotonin/ immune-system.

html

>

>

>

> This article may explain the problems with poor smooth muscle

>

> relaxation ie innability to cry, digestive problems, post nasal drip,

>

> sinisitus, dry eyes, blurred vision, joint and muscle pains.

>

>

>

> When your immune system is down you don't block as many white blood

>

> cells, which in turn destroys prostagladin E1.

>

>

>

> The only way to get prostagladin E1 back to normal would be to create

>

> an absolutely huge rush of oxytocin, which is what seemed to happen

>

> with MDMA, sleep deprivation, amphetamine, exercise. At least

>

> subjectively speaking, the " loved up feeling, " was always shortly

>

> followed by a crying spell or an erection.

>

[Guest guest]

There is something else I forgot to mention. I think Vornan has tried

other drugs which act on several monoamiones (Aorix or soemehing?)

These drugs can improve libido, as I would have expected. But what

about sleep deprivation and MDMA? I suspect there is a pretty strong

difference. The same chemicals are increased, but there are several

other interaction that you may not get with MAOs eg. histamine,

muscarinic receptors, oxytocin.

Subjectively speaking it felt like PE 1 and oxytocin primarily. But

why has this not worked for others before?

> >

> > http://www.biopsychiatry.com/serotonin/immune-system.html

> >

> > This article may explain the problems with poor smooth muscle

> > relaxation ie innability to cry, digestive problems, post nasal

drip,

> > sinisitus, dry eyes, blurred vision, joint and muscle pains.

> >

> > When your immune system is down you don't block as many white

blood

> > cells, which in turn destroys prostagladin E1.

> >

> > The only way to get prostagladin E1 back to normal would be to

create

> > an absolutely huge rush of oxytocin, which is what seemed to

happen

> > with MDMA, sleep deprivation, amphetamine, exercise. At least

> > subjectively speaking, the " loved up feeling, " was always shortly

> > followed by a crying spell or an erection.

> >

>

[Guest guest]

" why has this not worked for others before? "

I'm not sure what exactly your question refers to.

But I know that oxytocin does nothing for libido.

Oxytocin level spikes after sex, not during arousal.

Exogenously administered oxytocin only leads to a bathroom visit.

This is good if your constipated, but does nothing for PSSD.

Sleep deprivation acts as a mild agonist for dopamine, so it does

cause a slight temporary and noticeable increase in sexual function.

Not much is really known about MDMA. I'm sure it acts on mechanisms

that are still unknown. And it is toxic. It can only be taken a few

times before it makes one miserable. I did find one case report where

a guy accidentally gave his father with Parkinson's disease a dose and

it gave a dramatic but temporary symptom relief for PD. Some people

say that it's good for sex, but there is also conflicting info saying

that it causes impotence.

I think that high histamine level is also part of the constellation of

hormone imbalance involved with PSSD.

I don't remember much about the muscarinic system offhand, so I won't

comment on that.

Drugs like Requip, cabergoline, melanotan-2, have given temporary

relief. Requip, only 1mg should be used. Subsequent doses have

diminishing returns. Cabergoline, subsequent doses have diminishing

returns. In either case, more is not better. Cabergoline doesn't have

the bothersome side effects that Requip does. But evidence shows that

cabergoline can damage the heart.

And the effect is very un-natural. For the duration of the effect of

either drug, it's impossible not to think about sex. (especially the

cabergoline)And if you don't have a sexual partner while using it, it

is torture. And then it's back to the same old torturous numbness.

Some people find melantotan-2 very hard to tolerate, and the erections

happen at random, disturbing sleep several times during the night,

which can be a real annoyance. The shakes, headaches, nausea, can be

bad enough to out-weigh the benefit. I think others have found ways to

minimize those side effects though. It is also un-natural feeling, but

there is more sexual feeling. Sometimes that is better than nothing

though. Some people take a low dose in the morning after breakfast and

find that it's helpful. Also, doses vary by individual.

I think there's somewhat of an unofficial consensus that Arorix does

little or nothing for PSSD. My PSSD lab rat would bite my hand off if

I try to give him any more psych drugs.

I haven't done any research on PE 1, but there is a possibility it

could be involved in future experiments. Some anecdotal reports show

that pgcl increases libido, but the side effect is a guaranteed visit

to the bathroom. This substance won't be available to me for a few

months, so it will take some time before I can report back with any

more information about it.

SRIsex , " pssd24 " wrote:

>

> There is something else I forgot to mention. I think Vornan has tried

> other drugs which act on several monoamiones (Aorix or soemehing?)

>

> These drugs can improve libido, as I would have expected. But what

> about sleep deprivation and MDMA? I suspect there is a pretty strong

> difference. The same chemicals are increased, but there are several

> other interaction that you may not get with MAOs eg. histamine,

> muscarinic receptors, oxytocin.

>

> Subjectively speaking it felt like PE 1 and oxytocin primarily. But

> why has this not worked for others before?

>

>

> > >

> > > http://www.biopsychiatry.com/serotonin/immune-system.html

> > >

> > > This article may explain the problems with poor smooth muscle

> > > relaxation ie innability to cry, digestive problems, post nasal

> drip,

> > > sinisitus, dry eyes, blurred vision, joint and muscle pains.

> > >

> > > When your immune system is down you don't block as many white

> blood

> > > cells, which in turn destroys prostagladin E1.

> > >

> > > The only way to get prostagladin E1 back to normal would be to

> create

> > > an absolutely huge rush of oxytocin, which is what seemed to

> happen

> > > with MDMA, sleep deprivation, amphetamine, exercise. At least

> > > subjectively speaking, the " loved up feeling, " was always shortly

> > > followed by a crying spell or an erection.

> > >

> >

>

[Guest guest]

Its possible that the erectile effect is mediated by calcium

channels. This is another possible effect of MDMA. Other options are

I suppose monoamines, histamine, muscarine, and gaba.

> > From: pssd24 <pssd24@>

> > Subject: SSRIs may change immune system response

> > To: SSRIsex

> > Date: Tuesday, July 15, 2008, 10:13 AM

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > http://www.biopsych iatry.com/ serotonin/ immune-

system.

> html

> >

> >

> >

> > This article may explain the problems with poor smooth muscle

> >

> > relaxation ie innability to cry, digestive problems, post nasal

drip,

> >

> > sinisitus, dry eyes, blurred vision, joint and muscle pains.

> >

> >

> >

> > When your immune system is down you don't block as many white

blood

> >

> > cells, which in turn destroys prostagladin E1.

> >

> >

> >

> > The only way to get prostagladin E1 back to normal would be to

create

> >

> > an absolutely huge rush of oxytocin, which is what seemed to

happen

> >

> > with MDMA, sleep deprivation, amphetamine, exercise. At least

> >

> > subjectively speaking, the " loved up feeling, " was always shortly

> >

> > followed by a crying spell or an erection.

> >

>

[Guest guest]

Anti-depressant drugs could be causing diseases like lupus.

I'm sure that big pharma is trying to figure a way to advertise this

as a good thing. Here's an article about it, citing the lead

researcher from the biopsychiatry link below. (Gerard Ahern, Ph.D.)

http://www.onthewhole.info/bodymind_connection/index.html

> >

> > http://www.biopsychiatry.com/serotonin/immune-system.html

> >

> > This article may explain the problems with poor smooth muscle

> > relaxation ie innability to cry, digestive problems, post nasal drip,

> > sinisitus, dry eyes, blurred vision, joint and muscle pains.

> >

> > When your immune system is down you don't block as many white blood

> > cells, which in turn destroys prostagladin E1.

> >

> > The only way to get prostagladin E1 back to normal would be to create

> > an absolutely huge rush of oxytocin, which is what seemed to happen

> > with MDMA, sleep deprivation, amphetamine, exercise. At least

> > subjectively speaking, the " loved up feeling, " was always shortly

> > followed by a crying spell or an erection.

> >

>

[Guest guest]

Benedril=low histamine

Prozac=high histmaine

Both drugs cause sexual problems.

So they both must have a common link other than histamine that is

causing the problem. I know that they both raise serotonin.

But I've never seen anything that proves high serotonin is the real

cause. Does high serotonin last for years after discontinuation?

> > > > >

> > > > > http://www.biopsychiatry.com/serotonin/immune-system.html

> > > > >

> > > > > This article may explain the problems with poor smooth muscle

> > > > > relaxation ie innability to cry, digestive problems, post

> nasal

> > > drip,

> > > > > sinisitus, dry eyes, blurred vision, joint and muscle pains.

> > > > >

> > > > > When your immune system is down you don't block as many white

> > > blood

> > > > > cells, which in turn destroys prostagladin E1.

> > > > >

> > > > > The only way to get prostagladin E1 back to normal would be

> to

> > > create

> > > > > an absolutely huge rush of oxytocin, which is what seemed to

> > > happen

> > > > > with MDMA, sleep deprivation, amphetamine, exercise. At least

> > > > > subjectively speaking, the " loved up feeling, " was always

> shortly

> > > > > followed by a crying spell or an erection.

> > > > >

> > > >

> > >

> >

>