Re: RESEARCH - GI prophylactic therapy among patients with arthritis treated by rheumatology specialists

[Guest guest]

Hi ,

Thanks for this information. I have OA and FM. My rheum gives me

Lodine for both my diagnosis as advised by my gastro. Because I take

Lodine, my gastro gives me Cytotec and Reglan to protect my stomach.

I also take Carafate for another problem, and it protects my

stomach. I am thankful my rheum and gastro work together even though

they aren't with the same clinic.

Debbie L

>

> J Rheumatol. 2006 Apr;33(4):779-84. Epub 2006 Mar 1.

>

>

> Gastrointestinal prophylactic therapy among patients with

arthritis treated

> by rheumatology specialists.

>

>

> EB, Michaud K, Wolfe F.

>

> Brigham and Women's Hospital, Boston, Massachusetts, USA.

>

> OBJECTIVE: To determine rates of gastroprotective agent (GPA) use

among

> patients with arthritis treated by rheumatologists, and to

determine factors

> associated with GPA prescription. METHODS: In a longitudinal

outcome study,

> 11,451 patients with rheumatoid arthritis (RA) and osteoarthritis

(OA)

> reported all medication use, ulcer history, functional status, and

> sociodemographic characteristics. RESULTS: GPA were used in 21-24%

of all

> patients with RA and OA and in about 35-40% of all high risk

patients. In

> unadjusted analyses, GPA use was similar among NSAID users and non-

users. In

> multivariable logistic regression analyses GPA use was associated

with

> non-specific (NS) NSAID and COX-2 NSAID, prednisone, low dose

aspirin,

> comorbidity, Health Assessment Questionnaire functional score, age

< 65

> years, increased income, not smoking, and being male. Despite

numerous

> associations, the explanatory power for GPA use was poor (area

under ROC

> curve = 0.680).

>

> CONCLUSION: GPA are used in 35% to 40% of patients with 4 risk

factors for

> gastrointestinal ulceration. GPA use is not increased in NS NSAID

users

> compared to COX-2 NSAID users, and was inversely associated with

> socioeconomic status. GPA use does not follow the model predicted

by

> clinical trial results with respect to NS NSAID and age,

reflecting a change

> in the pattern of NSAID use in patients with rheumatic disease.

The major

> determinant of GPA use appears to be physician prescribing

behavior.

>

>

> PMID: 16511939

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=16511939

>

>

>

>

> Not an MD

>

> I'll tell you where to go!

>

> Mayo Clinic in Rochester

> http://www.mayoclinic.org/rochester

>

> s Hopkins Medicine

> http://www.hopkinsmedicine.org

>

[Guest guest]

You're welcome, Debbie. I'm glad your physicians are working together to

take good care of you.

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

[ ] Re: RESEARCH - GI prophylactic therapy among patients

with arthritis treated by rheumatology specialists

Hi ,

Thanks for this information. I have OA and FM. My rheum gives me

Lodine for both my diagnosis as advised by my gastro. Because I take

Lodine, my gastro gives me Cytotec and Reglan to protect my stomach.

I also take Carafate for another problem, and it protects my

stomach. I am thankful my rheum and gastro work together even though

they aren't with the same clinic.

Debbie L

[Guest guest]

This reminded me of the hospital stay 2 weeks ago. Usually, they confiscate

any meds we bring, and decide for themselves what we need. Well, it turns

out that I wasn't getting my meds, only a couple of new pills I've never

seen and wasn't conscious enough to pay attention to what I was being given.

I need Lodine XL, but the whole big hospital with it's great pharmacy only

had Motrin! That would attack my liver, so I was told after missing a couple

of doses, and was asked to bring mine from home. Because of the meds held

back, my back is inflamed again, pinching the Sciatic nerve, making my back

and leg a pain level of 8-9 all the time. he only thing I can do is take

more Prednisone until it gets back to where it's supposed to be. That's the

'professional' opinion of a Pain Management doctor. My attitude isn't any

better and actually getting worse.

Dennis

[ ] Re: RESEARCH - GI prophylactic therapy among patients

with arthritis treated by rheumatology specialists

Hi ,

Thanks for this information. I have OA and FM. My rheum gives me

Lodine for both my diagnosis as advised by my gastro. Because I take

Lodine, my gastro gives me Cytotec and Reglan to protect my stomach.

I also take Carafate for another problem, and it protects my

stomach. I am thankful my rheum and gastro work together even though

they aren't with the same clinic.

Debbie L

>

> J Rheumatol. 2006 Apr;33(4):779-84. Epub 2006 Mar 1.

>

>

> Gastrointestinal prophylactic therapy among patients with

arthritis treated

> by rheumatology specialists.

>

>

> EB, Michaud K, Wolfe F.

>

> Brigham and Women's Hospital, Boston, Massachusetts, USA.

>

> OBJECTIVE: To determine rates of gastroprotective agent (GPA) use

among

> patients with arthritis treated by rheumatologists, and to

determine factors

> associated with GPA prescription. METHODS: In a longitudinal

outcome study,

> 11,451 patients with rheumatoid arthritis (RA) and osteoarthritis

(OA)

> reported all medication use, ulcer history, functional status, and

> sociodemographic characteristics. RESULTS: GPA were used in 21-24%

of all

> patients with RA and OA and in about 35-40% of all high risk

patients. In

> unadjusted analyses, GPA use was similar among NSAID users and non-

users. In

> multivariable logistic regression analyses GPA use was associated

with

> non-specific (NS) NSAID and COX-2 NSAID, prednisone, low dose

aspirin,

> comorbidity, Health Assessment Questionnaire functional score, age

< 65

> years, increased income, not smoking, and being male. Despite

numerous

> associations, the explanatory power for GPA use was poor (area

under ROC

> curve = 0.680).

>

> CONCLUSION: GPA are used in 35% to 40% of patients with 4 risk

factors for

> gastrointestinal ulceration. GPA use is not increased in NS NSAID

users

> compared to COX-2 NSAID users, and was inversely associated with

> socioeconomic status. GPA use does not follow the model predicted

by

> clinical trial results with respect to NS NSAID and age,

reflecting a change

> in the pattern of NSAID use in patients with rheumatic disease.

The major

> determinant of GPA use appears to be physician prescribing

behavior.

>

>

> PMID: 16511939

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=16511939

>

>

>

>

> Not an MD

>

> I'll tell you where to go!

>

> Mayo Clinic in Rochester

> http://www.mayoclinic.org/rochester

>

> s Hopkins Medicine

> http://www.hopkinsmedicine.org

>