Oxytocin effect on DHT in the prostate

[Guest guest]

http://doi.wiley.com/10.1002/pros.20671

[Guest guest]

5a-reductase is the enzyme that converts hormones from one type to

another. For example, testosteron to estrogen. The receptors are what

monitor the hormone levels and balance things out by the feedback

inhibition mechanism.

If oxytocin raises this enzyme, what would be the consequence?

Faster conversion of hormones?

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[Guest guest]

I've been taking Oxytocin capsules (prescribed by Dr Shippen) after my

Saw Palmetto incident - he said they help make orgasm more

pleasurable. I just received a refill as I've ran out the last 2

weeks so I can compare/contrast and see if there's any difference in

pleasure. so to speak.

He also prescribed topical Selegiline (gel, not the patch) as it's

been reported known to help libido.

Paxil and all these other SSRIs must have some sort of effect on the

prostate. Before Paxil I was able to ejaculate with force/distance,

and then with Paxil it became retrograde. After stopping, it's still

retrograde (and now with SPE troubles there's less volume and it's a

lot thicker). Libido was never the same after Paxil but at least I

had some - SPE nearly wiped it out.

Also. after quitting Paxil, I went from being able to go all night (as

most SSRIs do) to nearly premature ejaculation. Some docs prescribe

SSRIs just to help PE for men. It's somewhat improved but I really

messed things up by taking Saw Palmetto, in 9 days no less. After

Paxil, I should've sworn off any sort of supplement/AD/etc.

I don't know what to do about the genital numbness - this presented

itself after stopping Saw Palmetto (not Paxil) and it's been over 5

months with little improvement. There has to be a link between the

prostate and genital numbness (androgen receptors perhaps?).

One person over on the Propeciahelp forum found great relief after

using Xyrem (prescription form of GHB). His libido skyrocketed, had

stronger erections, and better stamina. He also felt mentally

refreshed and recovered a normal sleeping pattern (had insomnia issues

as well as sexual problems from Propecia). His sexual problems

recovered in nearly a week and had a lasting/correcting effect.

Anyway, there must be some sort of common link between the problems of

SSRIs and DHT inhibitors, but what? 5AR? Androgen receptors?

Neurosteroids? And how can it be fixed?

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[Guest guest]

I agree with you that SSri;s seem to impact our prostate. I too could

ejaculate with firce and distance prior to taking ssri's, now its

less volume, alot thick er does have much force.

I have noticed PC Exercises may help, the muscles uyou could contract

whilst urinating. I have noticed how weak my muscles have become down

there. I can hardly contract my pc muscles for 2-3 seconds, and you

suppose to be able to contract for atleast 15-30 seconds. Have ssri's

made our muscles generally weak, espeacially the PC muscle

responsible for stronger erections and ejaculating force?

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