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Tumuric is possbility for PSSD depresion

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I've been trying tumeric for depression/lethargy and tiredness.

The good thing about this drug is that it interacts with the 5ht1a,

5ht1b and 5ht2c repeptors. This should help to reduce slow wave sleep

and deep sleep, and increease wakefullness. The other thing it does is

increases serotonin and dopamine (obviously increasing wakefullness).

I think really the root cause of pssd is that serotonin receptors in

the dorsal raphe and or hypothalumus do not work properly, causing too

much slow wave sleep, loss of dreams, poor REM sleep, lack of

wakefullness. In the long run, this could effect the hypothalumus

sleep/wake switch causing reductions in dopamine, cortisol,

testosterone, oxytocin, poor neurotransmission at 5ht2a, 5ht2c, a1

sites, and lack of nitric oxide. I believe that this is why very severe

sleep deprivation temporarily cures all aspects of pssd.

I'm not sure whether tumeric would help with this or not, for instance,

will it pass the blood brain barrier?

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