Guest guest Posted May 11, 2006 Report Share Posted May 11, 2006 Hi all, I have a question about how long it takes before I start seeing results with methotrexate. I have been taking the oral mtx for 7 weeks (tomorrow will be week 8). Now that I have ramped up the folic acid, I don't get really bad side effects, just the brain fog and hangover that comes the next day. But I was up most of the night with a lot of pain in my wrists, and now I am having pain in my knees ankles and feet. It is so bad that I can't even bathe my 20 month old, I am afraid of dropping her. I am also on Relafen. I thought I would start feeling a little better by now, but my pain seems to be the same or worse and is moving around now, before it was just in my wrists primarily. Maybe my dosage will need to be increased at my next rheumy visit on the 22nd?? I am fairly new to all of this and it is pretty scary. Quote Link to comment Share on other sites More sharing options...
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