RESEARCH - Frequency of osteoporosis in 187 men with RA followed in a university hospital

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J Rheumatol. 2006 Aug;33(8):1472-5.

Frequency of osteoporosis in 187 men with rheumatoid arthritis followed in a

university hospital.

Nolla JM, Roig-Vilaseca D, Gomez-Vaquero C, Mateo L, ola X,

-Moreno J, Narvaez J, Valverde J.

From the Rheumatology Department, IDIBELL-Hospital Universitari de

Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.

OBJECTIVE: Although there is relevant information on frequency of

osteoporosis in women with rheumatoid arthritis (RA), data about male

patients are limited. We evaluated the frequency of osteoporosis in a group

of Spanish men with RA followed in a university hospital. METHODS: From the

database of our bone densitometry unit, we searched for men with RA

evaluated between January 1991 and December 2004 and identified 187

patients, 156 of whom were older than 50 years. Previously recorded

demographic, disease, and treatment-related variables were collected. Bone

mineral density (BMD) was measured by dual x-ray absorptiometry (DEXA).

Osteoporosis was defined according to the criteria of the World Health

Organization (WHO), recommended for postmenopausal Caucasian women, as a T

score </= -2.5 SD, and the International Society for Clinical Densitometry

(ISCD), which indicates the same diagnostic threshold, but only in men over

age 50 years. RESULTS: BMD was lower than in the general population in both

lumbar spine [Z score -0.41 +/- 1.00 (95% CI -0.55 to -0.26)] and femoral

neck [Z score -0.46 +/- 0.95 (95% CI -0.60 to -0.31)]. When the WHO

threshold for postmenopausal women was applied, frequency of osteoporosis

was 13% at lumbar spine, 12% at the femoral neck, and 21% in at least one of

the evaluated sites. When ISCD criteria were applied, the frequency of

osteoporosis was 13%, 14%, and 23%, respectively.

CONCLUSION: Frequency of osteoporosis in men is considerably lower than that

traditionally established in women with RA, independent of the diagnostic

criteria applied.

PMID: 16881105

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=1\

6881105

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