Guest guest Posted December 23, 2006 Report Share Posted December 23, 2006 Hi all. I wrote in last week to ask about sero-negative RA. My first rheumatologist has diagnosed me with " undifferentiated polyarthritis " and wants me to start on a DMARD (Plaquenil or Methotrexate). I am getting a second opinion from a city rheumatologist today. Meanwhile, several people I know are urging me to pursue a doctor who will agressively search for clinical or seriological signs of Lyme disease, which is very common in our part of Pennsylvania. We have a cat who brings ticks into the house from time to time, and I have been bitten before. I thought Lyme disease primarily affects large joints, but the woman I spoke to yesterday told me my symptoms (pain in hands, wrists, knees, ankles, balls of feet) are exactly the same as her early Lyme disease symptoms. I did have the ELISA test for Lyme which was negative. All of my blood work so far (including RF) has been completely normal, and xrays of hands and feet taken last week are also normal. However, I don't want to waste time pursuing a possible Lyme disease diagnosis and miss a " window of opportunity " for treating what could be early RA. Aarrgghh! I feel so confused. Has anyone in this group been diagnosed, correctly or incorrectly, with Lyme Disease? Meg in Pennsylvania Quote Link to comment Share on other sites More sharing options...
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