RESEARCH - Sensitivity to UV light during treatment with chloroquine

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Scand J Rheumatol. 1992;21(5):245-7.

Sensitivity to UV light during treatment with chloroquine in rheumatoid

arthritis.

Seideman P, Ros AM.

Department of Internal Medicine, Karolinska Institutet, Danderyd Hospital,

Sweden.

Chloroquine and hydroxychloroquine have long been suspected of causing light

sensitivity in patients with rheumatoid arthritis (RA). To gain insight into

the effect of chloroquines and ultraviolet (UV) light in RA we have

phototested 25 RA patients with and without chloroquine. The thresholds for

UVA and UVB did not change upon treatment with chloroquine or

hydroxychloroquine. Provocation with high dose UVA and UVB was similar with

and without treatment with chloroquine or hydroxychloroquine. Our results

have shown that photosensitivity during medication with chloroquine and

hydroxychloroquine is uncommon and that there is no need to stop this

treatment due to sun exposure.

PMID: 1439633

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=1439633

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