RESEARCH - Dysphagia in patients with primary and secondary Sjogren's syndrome

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Oral Surg Oral Med Oral Pathol Oral Radiol Endod.

1995 Mar;79(3):305-10.

Quantitative assessment of dysphagia in patients with primary and secondary

Sjogren's syndrome.

Rhodus NL, Colby S, Moller K, Bereuter J.

Division of Oral Medicine and Diagnosis, University of Minnesota,

Minneapolis, USA.

Dysphagia is a common complaint from patients with salivary gland

dysfunction. The purpose of this study was to assess and compare dysphagia

in two patient groups with salivary gland dysfunction (primary Sjorgen's

syndrome and secondary Sjogren's syndrome with systemic lupus erythematosus,

and a matched control group. Subjects diagnosed with primary Sjogren's

syndrome (n = 13) and secondary Sjogren's syndrome with systemic lupus

erythematosus (n = 15) were selected for the study. An age- and sex-matched

group of control subjects (n = 14) was selected for comparison. Dysphagia

assessments, including videofluoroscopy were performed. Dysphagia was

quantified clinically and videofluoroscopically by measurement of 10 seconds

of basal or dry swallows as compared with 10-second 10-ml water bolus

swallows in all subjects. Subjective evaluations were recorded on a

calibrated 10-cm visual analog scale. The results indicated a significant

difference in the dry swallows as compared with the water bolus swallows for

both salivary gland dysfunction groups and for both dry swallows and water

bolus swallows as compared to controls. Videofluoroscopy yielded

significantly prolonged pharyngeal transit times in both salivary gland

dysfunction groups as compared with control. Subjective results indicated a

greater degree of dysphagia symptoms in both the salivary gland dysfunction

groups (p < 0.001). Conclusions from this study indicate clinically

significant dysphagia in patients with salivary gland dysfunction associated

with Sjogren's syndrome compared with a control population.

PMID: 7621008

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=7\

621008 & dopt=Abstract

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