RESEARCH - Peripheral neuropathy in two patients with RA receiving Remicade

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Clin Rheumatol. 2007 Feb;26(2):258-60. Epub 2006 Jul 6.

Peripheral neuropathy in two patients with rheumatoid arthritis receiving

infliximab treatment.

Department of Internal Medicine, Euroclinic Hospital, 9 Athanasiadou str,

115 21, Athens, Greece, mtektonidou@....

Antitumor necrosis alpha agents have been successfully used for the

treatment of rheumatoid and seronegative arthritis, Crohn's disease,

psoriasis, and severe cases of vasculitis. Several side effects have been

observed in patients receiving these agents including hypersensitivity

reactions, infections, drug-induced lupus, or demyelinating syndromes. The

presence of peripheral neuropathy has been reported only in isolated cases.

We describe two cases of peripheral neuropathy which occurred in patients

with rheumatoid arthritis receiving infliximab treatment, one with

multifocal motor neuropathy with conduction block and another with axonal

sensory polyneuropathy, reversed upon discontinuation of infliximab and

intravenous gammaglobulin treatment.

PMID: 16683176

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstra\

ctPlus & list_uids=16683176

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