RESEARCH - Diagnosis of primary Sjogren's syndrome in daily practice: a retrospective analysis

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Rheumatol Int. 2007 Jan 25; [Epub ahead of print]

Use of the European preliminary criteria, the Breiman-classification tree

and the American-European criteria for diagnosis of primary Sjogren's

Syndrome in daily practice: a retrospective analysis.

Clinical Department of Internal Medicine, Innsbruck Medical University,

Anichstrasse 35, 6020, Innsbruck, Austria.

This study was conducted to assess the use of the European preliminary

criteria, the Breiman-classification tree and the American-European criteria

for diagnosis of primary Sjogren's Syndrome (pSS) in daily practice. A

retrospective analysis of 17 consecutive patients with pSS (European

criteria) was performed evaluating the application of the Schirmer test,

semiquantitative sialoscintigraphy, immunologic tests, including rheumatoid

factor, antinuclear antibodies, Sjogren's syndrome autoantibodies (SS-A,

SS- and lip biopsy. Out of the 17 patients with pSS according to the

European criteria, 15 patients fulfilled the classification tree (=88.2%),

and 4 patients fulfilled the American-European criteria (=23.5%, P = 0.001).

In the four patients fulfilling the American-European criteria, a positive

result of the sialoscintigraphy was not crucial for the diagnosis according

to these criteria. In conclusion, the American-European criteria are more

stringent than the European preliminary criteria. We assume the role of

sialoscintigraphy to be reduced when applying the American-European

criteria.

PMID: 17252265

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstra\

ctPlus & list_uids=17252265

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