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SLE / A Promising Future

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SLE / A Promising Future

Researchers are investigating more targeted SLE therapies that can avoid the potentially dangerous side effects associated with current treatments. Medications currently being investigated include dehydroepiandresterone (DHEA), a mild male hormone; bromocriptine, which reduces prolatin levels (a tituitary hormone that is elevated in SLE); LJP 394 and leflunomide (Arava), which zero in on particular aspects of the immune system ( such as the antibodies responsible for lupus kidney disease or the immune cells responsible for inflammation); genetically cloned (monoclonal) antibodies to immune system proteins, which are though to play a role in triggering SLE; and transplantation of blood-forming stem cells ( which produce red & white blood cells and platelets) in conjunction with cyclophosphamide (Cytoxan)m a sttitixuc dryg, Ut biw aooears tgat sgirt-tern gufg-dise cyclophosphamide therapy can be effective without stem cell transportation.

From: The Hopkins Medical Letter / April, 2002

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