Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 This is an excerpt from a WHO paper on mercury, from the 1980s. Radhe The oxidation of elemental mercury vapour in the body (section 6.1.1) can be reduced considerably (to about 50% of normal values) by moderate amounts of alcohol. In an in vivo study, the uptake of labelled mercury into human red cells was reduced by almost a factor of ten by etha- nol, while there was an increase in liver mercury concen- trations (Hursh et al., 1980). Observations on rats, mice, and monkeys confirm these results (Khayat & Dencker, 1983a,b, 1984). They also show a marked decrease in mer- cury concentrations in several organs, including the brain. However, somewhat higher concentrations of mercury were observed in the brain and liver of pregnant mice with a congenital catalase deficiency that were exposed for 1 h to metallic mercury vapour during day 18 of gestation (Ogata & Meguro, 1986). The blood mercury concentration in the catalase-deficient mice was only about half of that in the control mice. The uptake in the fetus was 2% of the dose compared to 1.2% for the controls. Lower mercury levels have been observed in the brain tissue of humans classified as chronic alcohol abusers than in controls (Fig. 3). Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 17, 2008 Report Share Posted January 17, 2008 Well working in the mental health field, I've seen many people abuse substances as self- medication. Thanks for shedding a new angle on this for me! Exchanging one toxin for another- fascinating. > > This is an excerpt from a WHO paper on mercury, from the 1980s. > Radhe > > > The oxidation of elemental mercury vapour in the body > (section 6.1.1) can be reduced considerably (to about 50% > of normal values) by moderate amounts of alcohol. In an > in vivo study, the uptake of labelled mercury into human > red cells was reduced by almost a factor of ten by etha- > nol, while there was an increase in liver mercury concen- > trations (Hursh et al., 1980). Observations on rats, mice, > and monkeys confirm these results (Khayat & Dencker, > 1983a,b, 1984). They also show a marked decrease in mer- > cury concentrations in several organs, including the > brain. However, somewhat higher concentrations of mercury > were observed in the brain and liver of pregnant mice with > a congenital catalase deficiency that were exposed for 1 h > to metallic mercury vapour during day 18 of gestation > (Ogata & Meguro, 1986). The blood mercury concentration > in the catalase-deficient mice was only about half of that > in the control mice. The uptake in the fetus was 2% of the > dose compared to 1.2% for the controls. > > Lower mercury levels have been observed in the brain > tissue of humans classified as chronic alcohol abusers > than in controls (Fig. 3). > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 17, 2008 Report Share Posted January 17, 2008 Interesting, thanks for posting that. hmmm, on the other hand I cannot see that this effect of alcohol would bring such instantaneous but short-lasting changes in those individuals.. think it would be more of a gradual change and would be more long-lived than what is observed here. The same with alcohol - its supressing bacteria... don't see how it could kill it off to such an amazing extent within minutes of entering the body.. well then, who knows. I would still place my bet on instant effect being down to it reducing levels of cytokines. Or both. Natasa > > This is an excerpt from a WHO paper on mercury, from the 1980s. > Radhe > > > The oxidation of elemental mercury vapour in the body > (section 6.1.1) can be reduced considerably (to about 50% > of normal values) by moderate amounts of alcohol. In an > in vivo study, the uptake of labelled mercury into human > red cells was reduced by almost a factor of ten by etha- > nol, while there was an increase in liver mercury concen- > trations (Hursh et al., 1980). Observations on rats, mice, > and monkeys confirm these results (Khayat & Dencker, > 1983a,b, 1984). They also show a marked decrease in mer- > cury concentrations in several organs, including the > brain. However, somewhat higher concentrations of mercury > were observed in the brain and liver of pregnant mice with > a congenital catalase deficiency that were exposed for 1 h > to metallic mercury vapour during day 18 of gestation > (Ogata & Meguro, 1986). The blood mercury concentration > in the catalase-deficient mice was only about half of that > in the control mice. The uptake in the fetus was 2% of the > dose compared to 1.2% for the controls. > > Lower mercury levels have been observed in the brain > tissue of humans classified as chronic alcohol abusers > than in controls (Fig. 3). > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 17, 2008 Report Share Posted January 17, 2008 , you then may be aware that smoking is much more prevalent in scizophrenics than in general population. It is indeed some form of self-medication, as nicotine has effects on those very receptors in the brain that several of the drugs given to them by doctors do. Natasa > > > > This is an excerpt from a WHO paper on mercury, from the 1980s. > > Radhe > > > > > > The oxidation of elemental mercury vapour in the body > > (section 6.1.1) can be reduced considerably (to about 50% > > of normal values) by moderate amounts of alcohol. In an > > in vivo study, the uptake of labelled mercury into human > > red cells was reduced by almost a factor of ten by etha- > > nol, while there was an increase in liver mercury concen- > > trations (Hursh et al., 1980). Observations on rats, mice, > > and monkeys confirm these results (Khayat & Dencker, > > 1983a,b, 1984). They also show a marked decrease in mer- > > cury concentrations in several organs, including the > > brain. However, somewhat higher concentrations of mercury > > were observed in the brain and liver of pregnant mice with > > a congenital catalase deficiency that were exposed for 1 h > > to metallic mercury vapour during day 18 of gestation > > (Ogata & Meguro, 1986). The blood mercury concentration > > in the catalase-deficient mice was only about half of that > > in the control mice. The uptake in the fetus was 2% of the > > dose compared to 1.2% for the controls. > > > > Lower mercury levels have been observed in the brain > > tissue of humans classified as chronic alcohol abusers > > than in controls (Fig. 3). > > > Quote Link to comment Share on other sites More sharing options...
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