Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 If anyone else felt my posted was in poor taste. I'm truly sorry. I never meant to offend anyone, except my toe! I love reading everyone's stories and helping out when I can. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 At 10:11 AM 9/14/99 EDT, you wrote: >From: DaniGran@... > >If anyone else felt my posted was in poor taste. I'm truly sorry. I never >meant to offend anyone, except my toe! Not offended at all, I think the reaction you got was somewhat overdone, but to not clutter the list I did not react. It should be OK to post something like that on the list, because sometimes at home you get to hear: " I don't want to hear about your toes today. " Or something like that. Take care and good luck. Btw, I bought a wooden massage thing where you can roll your foot over, that's nice, though a personal massage is better. Eliane Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 1999 Report Share Posted December 27, 1999 In a message dated 12/27/99 5:38:06 AM Pacific Daylight Time, onelist writes: << A while back there was a call for people to give in their personal stories of treatment success, so that these could be read by others. Have these been put onto the web ?? As one of the " others " at the start of the treatment process I am keen to read the stories and especially keen to show them to other local parents who are still being given the " lifelong incurable developmental disorder " line ... >> I'm not sure about your question on a big scale but our story is on my website...talks about the ways we found to help our autistic son acquire language and develop play skills and some social understanding. Check it out at: http://www.homestead.com/wholefamily/wholefamily1.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 30, 2002 Report Share Posted January 30, 2002 Excues the caps, KAREN, TELL HIM TO GET ANOTHER DOCTOR! That Dr. sounds like the most ignorant, uninformed sob I ever heard of. All the info he has given you is not up-to-date and now wonder it scared the hell out of you all! Like I said earlier, I just found out my 21 yr. old son has hepc so you are not the only Mom going through this. He is looking at his life like, how will I ever find someone to accept this? However, because I've been a part of this group for over a year now, I have mega hope for him. He will get through this. There are many different stages we go through when we find out we have this dreadful disease. We finally end up at acceptance and then our life goes on again. Time is definitely on his side. Just hang in there and keep hanging with us! I don't mean to ignore everyone else and you are all in my prayers. Hey , CONGRATULATIONS ON YOUR COMPLETION OF TREATMENT! Love, Vicky Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 30, 2002 Report Share Posted January 30, 2002 Thank you Vicky and I will tell him he has got to make good decisions on medical care and quickly before him and his wife throw their lives away on nonsense. Vicky I just have to believe that your son will find someone that can see him for who he really is. And my personal belief is no one is their illness or diagnosis. It will help him immeasureably too to have a mom who has lived this. All I could do when Greg called me is wring my hands in despair and try hard not to freak out. I know this much. His wife is pretty scared. I don't blame her but if they can give her the real facts not just some scare talk maybe that will help this whole ordeal tremendously. Yes we all have had the heck scared out of us. I will be trying to talk to my son soon. Hopefully we can get the misinformation situation resolved and that alone should help. > Excues the caps, KAREN, TELL HIM TO GET ANOTHER DOCTOR! That Dr. sounds like > the most ignorant, uninformed sob I ever heard of. All the info he has given > you is not up-to-date and now wonder it scared the hell out of you all! Like > I said earlier, I just found out my 21 yr. old son has hepc so you are not > the only Mom going through this. He is looking at his life like, how will I > ever find someone to accept this? However, because I've been a part of this > group for over a year now, I have mega hope for him. He will get through > this. There are many different stages we go through when we find out we have > this dreadful disease. We finally end up at acceptance and then our life > goes on again. Time is definitely on his side. Just hang in there and keep > hanging with us! I don't mean to ignore everyone else and you are all in my > prayers. Hey , CONGRATULATIONS ON YOUR COMPLETION OF TREATMENT! > > Love, Vicky Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 1, 2002 Report Share Posted February 1, 2002 Thanks Vicky Re: [ ] Digest Number 271 Excues the caps, KAREN, TELL HIM TO GET ANOTHER DOCTOR! That Dr. sounds like the most ignorant, uninformed sob I ever heard of. All the info he has given you is not up-to-date and now wonder it scared the hell out of you all! Like I said earlier, I just found out my 21 yr. old son has hepc so you are not the only Mom going through this. He is looking at his life like, how will I ever find someone to accept this? However, because I've been a part of this group for over a year now, I have mega hope for him. He will get through this. There are many different stages we go through when we find out we have this dreadful disease. We finally end up at acceptance and then our life goes on again. Time is definitely on his side. Just hang in there and keep hanging with us! I don't mean to ignore everyone else and you are all in my prayers. Hey , CONGRATULATIONS ON YOUR COMPLETION OF TREATMENT! Love, Vicky Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 22, 2003 Report Share Posted January 22, 2003 In a message dated 1/22/2003 8:24:10 AM Eastern Standard Time, writes: > Weird, huh? > Weird and Wonderful! lol Vickie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2004 Report Share Posted August 28, 2004 wrote: > Hey Don > > Thanks for all the info!!!! It is very helpful. > > > > Our digestive enzymes are needed to but not for digesting our > > food. This is why we eat raw food so that the enzymes in the food will > > do the digesting. > > > Boy did I get off track here. Sheesh. > > I have been studying Taoism for years and found the Tao of Health by > Reid (hope it is okay to cite my source as I cannot take credit for > another's work - if I err I apologize as I am new to lists) and he > discusses much of these concepts in his book. I was introduced to > Trophology: The science of Food Combining. Chinese medicine sees > <<<Food is medicine>>>> and they have a system for eating it. At the > Tao Temple they are even more restrictive. Not into garlic and onions > to make us gentler - I found this does not work for me. I tried it and > yes I felt softer - more rose quartz - yet it is the wolf in me I need > to encourage. To see all I can see to make the best choices for ME. > And While it is an older book it at the time it was synchronistic for > me - I was open to learning. > > He cites many studies that show people all over the world in poverty > who consume about half the calories of the average teen show less signs > of nutritional defIciencies because of their diet. Blew me away! > Pasteurization is so evil - and milk curdles in the stomach inhibiting > absorption of the nutrients, etc. He also discusses the vital > importance of digestive enzymes!!! There is a quote in the book by an > doctor earlier that states that the only food that should be eaten is > food that will decay/rot if not. We are all vampires. Life feeds upon > life - the lesson of growing up in the country. > > I was totally surprised as after moving to the city with those > wonderfully pretty supermarkets - I thought the food was better until I > started eating it - little taste. And again I thought it was my luck > of draw for a while. The ranchers/farmers I grew up around were > businessmen but most did not screw others to make a profit. Your > reputation was at stake. While I read all of this my heart has trouble > believing people are so uncaring to risks another's health. I want and > do believe in the goodness of others. It took years and having health > concerns of my own to see that - reality is relative. And change often > is threating as it opens the eye to see how much responsibility we must > take for our actions. Nobody forced me to eat. Or believe what I > believe. I chose my life as I choose it now. I don't think > discussing this is off topic as it is the 'why " - dirt matters. > > I bet you will be hopping around on Z Coils before you know it I > will be shortly........have a great day / night. What part of Europe? > > > > > " Spirit sleeps in the mineral, breathes in the vegetable, dreams in > > the animal and wakes in man. " > > I love this quote and hope to borrow it! > > Cath > > SHIN - A device for finding furniture in the dark. ================================== Hi Cath, I would prefer that everyone cite their sources so others can verify for themselves. You are most welcome, by the way. You have an interesting philosophy on life. Did you come by it naturally or did you, like me, get your education as the " School of Hard Knocks " ? LOL And I thought I was the only one who enjoyed this philosophy of life. ;-) You bet " Dirt Matters " it makes all the difference in the world. I checked out the web site for those Z-Coils and they are some pretty funky looking footwear. However, the guy just might have hit on a winner. There actually is a company over here that makes a brand of shoes that are supposedly ergonomically (or some such word) designed to be the perfect shoe. They look really funky too but not as funky as the Z-Coils. They are also quite a bit more expensive than the Z-Coils. Wonder how they compare? Anyway, they are supposedly designed to keep the foot perfectly flat and prevent turning of the ankles. I guess they are predominently running and hiking shoes. I am currently in Slovenia. Feel free to borrow the quote. I did. -- Peace, love and light, Don Quai " Spirit sleeps in the mineral, breathes in the vegetable, dreams in the animal and wakes in man. " Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 15, 2006 Report Share Posted April 15, 2006 Hi Angel, I wanted to post my comments on the inheritence aspect of heterochromia. I'm certainly not an expert but I am a scientist with a concentration in molecular biology and genetics who also has two different colored eyes. I wanted to send this information because I wasn't sure what you meant when you wrote about cross breeding. Heterochromia is an autosomal dominant trait. Dominant inheritance occurs when an abnormal gene from ONE parent is capable of causing disease even though the matching gene from the other parent is normal. The abnormal gene dominates the outcome of the gene pair. One of the parents will usually (but not always) have the disease or trait (since it is dominant). Only one parent must have an abnormal gene in order for the child to inherit the disease or trait. Recessive inheritance occurs when BOTH genes of a pair must be abnormal to produce disease. If only one gene in the pair is abnormal, the disease does not occur or is only mildly present. However, a person with a single defective gene is called a carrier, meaning the disease can be passed on to children. If one parent has an abnormal gene and the other parent a normal gene, there is a 50% chance each child will inherit the abnormal gene, and therefore the dominant trait. In other words, if it is assumed that 4 children are produced from a couple in which one parent has an abnormal gene for a dominant disease, the STATISTICAL expectation is for: 2 children normal 2 children with the disease This does not mean that children WILL necessarily be affected. It does mean that EACH child has a 50:50 chance of inheriting the disorder. Children who do not inherit the abnormal gene will not develop or pass on the disease. Tina --- heterochromia wrote: > There is 1 message in this issue. > > Topics in this digest: > > 1. Re: new member > From: " -varies- " <metalix77@...> > > > ________________________________________________________________________ > ________________________________________________________________________ > > Message: 1 > Date: Fri, 14 Apr 2006 19:40:15 -0000 > From: " -varies- " <metalix77@...> > Subject: Re: new member > > > > > > Hi, I just joined. My right eye has been very dark > brown from birth > > and my left was initially blue, then quickly > turned to a > > greenish/yellow/light brown. My great-grandmother > had different > > coloured eyes, but no-one else in my family. I > know that > heterochromia > > is an autosomal dominant trait, so why isn't > present in all > > generations? I read about gene penetrance, is this > the answer - does > > anyone know. > > Thanks. > > > > > Welcome to our ever expanding group. Through our > many hundreds of > posts, you should be able to find any information > there is related to > HC that so many of us have uncovered, some of which > can be very > interesting. If you have time, visit the database > and add your > details, so that we may keep a record of all of us > that visit! > > As for your question, I don't think (I'm not sure - > nearly everybody > in my family has it, though nobody has it like mine) > that it is > dominant. I've heard of some cases where it skips > many generations, so > I think it's recessive and not dominant, like when > parents are > surprised that their son/daughter has HC and > discover that their great > great great grandparents both had it and had a very > romantic life > because of it (just one case, but there would be > more). > > There's also a case where one of our own members has > HC, but not her > daughter, and a case where it is the reverse! > > There are different causes for HC, most of which are > genetic. I think > it originally came from cross breeding (happens a > lot in animals, even > today) in our ancestors, which led to a new mix of > genes, which led to > certain special features. This is a theory, which I > am still > investigating (in my sparse free time - college), > though it is > supported by most of the fact that most of us have > european ancestry. > > Hope this helps in some way ^^ > > Angel > > > > > > > > ________________________________________________________________________ > ________________________________________________________________________ > > > > ------------------------------------------------------------------------ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 17, 2006 Report Share Posted April 17, 2006 > > > > > > Hi, I just joined. My right eye has been very dark > > brown from birth > > > and my left was initially blue, then quickly > > turned to a > > > greenish/yellow/light brown. My great-grandmother > > had different > > > coloured eyes, but no-one else in my family. I > > know that > > heterochromia > > > is an autosomal dominant trait, so why isn't > > present in all > > > generations? I read about gene penetrance, is this > > the answer - does > > > anyone know. > > > Thanks. > > > > > > > > > Welcome to our ever expanding group. Through our > > many hundreds of > > posts, you should be able to find any information > > there is related to > > HC that so many of us have uncovered, some of which > > can be very > > interesting. If you have time, visit the database > > and add your > > details, so that we may keep a record of all of us > > that visit! > > > > As for your question, I don't think (I'm not sure - > > nearly everybody > > in my family has it, though nobody has it like mine) > > that it is > > dominant. I've heard of some cases where it skips > > many generations, so > > I think it's recessive and not dominant, like when > > parents are > > surprised that their son/daughter has HC and > > discover that their great > > great great grandparents both had it and had a very > > romantic life > > because of it (just one case, but there would be > > more). > > > > There's also a case where one of our own members has > > HC, but not her > > daughter, and a case where it is the reverse! > > > > There are different causes for HC, most of which are > > genetic. I think > > it originally came from cross breeding (happens a > > lot in animals, even > > today) in our ancestors, which led to a new mix of > > genes, which led to > > certain special features. This is a theory, which I > > am still > > investigating (in my sparse free time - college), > > though it is > > supported by most of the fact that most of us have > > european ancestry. > > > > Hope this helps in some way ^^ > > > > Angel > > > > > > > > > > > > > > > > > _____________________________________________________________________ ___ > > > _____________________________________________________________________ ___ > > > > > > > > > ------------------------------------------------------------------- ----- > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2006 Report Share Posted April 18, 2006 Hi - > Thanks for your imput. I'm also a scientist (reproductive and > developmental biology) - going back to my original question: We know > that heterochromia is an autosomal dominant trait, therefore if a > child is born with congenital heterochromia (in my case inherited > from a great-grandmother), then at least one parent must carry the > dominant gene, and subsequently one of the grandparents. In my case > both my parents and grandparents have 'normal' eyes as well as > numerous cousins and 5 siblings. Therefore the dominant gene is > obviously not being expressed in all carriers (ie. my father and my > grandmother). I've read about many people where this is also the > case. Do you know anything about gene penetrance? It seems that even > though the heterochromia gene is dominant - it must have a low > penetrance level? Any ideas.... > Thanks, . > Not a scientist myself, but work with genetics on a regular basis in poultry so I have a general understanding(ha!) of it. From what I've skimmed from the 'net so take that for it's worth.. the penetrance of heterochromia seems to be variable and dependent on which genetic cause it has. For example, in Waardenburg's syndrome(heterochromia is a common symptom) which is actually the name of several separate mutations- some are even on different chromosomes. They're categorized into " types " such as Waardenburg's Type I, II, etc. Anyways, according to what I read, the rates of heterochromia are very different between Waardenburg's Type I & II- much more common in II. Something like 10-20% & 40-50% respectively if I recall correctly(probably a bit off but that's the general idea of the penetrance difference). I also recall some studies which showed certain " lines " Waardenburg's(of either Type I or II) having higher or lower cases of heterochromia than the " norm " of that type(that is, those were independent mutations at the same loci as the others, so their copy was slightly different from the others.. I think?). So penetrance is variable.. no single simple answer for your question, I guess. Also, this might be a good area since you're in the field- have you thought about pigment cell migration? Most references if they mention it at all, regard heterochromia as hypnopigmentation of the affected eye.(for others- that means your blue or lighter eye is the " abnormal " eye). So it involves pigment cell migration in the neural crest of the embryo.. piebald critters are a good examples for studying this. In a lot of animals, if the pigment cells fail to reach the eye area, the result is a blue or considerably lighter eye-common cause of heterochromia in dogs and horses. Lastly, as for expression.. back to Waardenburg's, in addition to heterochromia, one of the symptoms is having *both* eyes hypnopigmented(brilliant blue is often mentioned). The thing is, if that happens in a family where blue eyes is already common & an individual has penetrance expression in both eyes making both blue or equally light colored, well, it won't stand out very much at all then, no? I have found no mention of how hypnopigmentation affects blue eyes.. my guess is none or very little? If that's the case, then that's one way it could pass through the generations " undetected " . It'd be obvious only in families with brown or otherwise colored eyes.. Just my thoughts resulting from excitement of reading this thread. (they need to make heterochromatic smileys!) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 23, 2006 Report Share Posted April 23, 2006 Re: Digest Number 271 Hi , I raise homing pigeons and heterochromia is fairly common in them but I haven't studied heterochromic inheritance in them yet. I have one hazel eye and one dark brown with no known heterochromic relatives,so I always thought my 'odd eyes' were the result of a mutation or a recessive gene. Jeff Not a scientist myself, but work with genetics on a regular basis inpoultry so I have a general understanding(ha!) of it.From what I've skimmed from the 'net so take that for it's worth.. thepenetrance of heterochromia seems to be variable and dependent onwhich genetic cause it has. For example, in Waardenburg'ssyndrome(heterochromia is a common symptom) which is actually the nameof several separate mutations- some are even on different chromosomes.They're categorized into "types" such as Waardenburg's Type I, II,etc. Anyways, according to what I read, the rates of heterochromia arevery different between Waardenburg's Type I & II- much more common inII. Something like 10-20% & 40-50% respectively if I recallcorrectly(probably a bit off but that's the general idea of thepenetrance difference). I also recall some studies which showedcertain "lines" Waardenburg's(of either Type I or II) having higher orlower cases of heterochromia than the "norm" of that type(that is,those were independent mutations at the same loci as the others, sotheir copy was slightly different from the others.. I think?). Sopenetrance is variable.. no single simple answer for your question, Iguess.Also, this might be a good area since you're in the field- have youthought about pigment cell migration? Most references if they mentionit at all, regard heterochromia as hypnopigmentation of the affectedeye.(for others- that means your blue or lighter eye is the "abnormal"eye). So it involves pigment cell migration in the neural crest of theembryo.. piebald critters are a good examples for studying this. In alot of animals, if the pigment cells fail to reach the eye area, theresult is a blue or considerably lighter eye-common cause ofheterochromia in dogs and horses. Lastly, as for expression.. back to Waardenburg's, in addition toheterochromia, one of the symptoms is having *both* eyeshypnopigmented(brilliant blue is often mentioned). The thing is, ifthat happens in a family where blue eyes is already common & anindividual has penetrance expression in both eyes making both blue orequally light colored, well, it won't stand out very much at all then,no? I have found no mention of how hypnopigmentation affects blueeyes.. my guess is none or very little? If that's the case, thenthat's one way it could pass through the generations "undetected".It'd be obvious only in families with brown or otherwise colored eyes.. Just my thoughts resulting from excitement of reading this thread. (they need to make heterochromatic smileys!) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 24, 2006 Report Share Posted April 24, 2006 Hi Jeff...U finally found us!...Tell Tammy to check this out....Steve Messenger with Voice. Make PC-to-Phone Calls to the US (and 30+ countries) for 2ยข/min or less. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 25, 2006 Report Share Posted April 25, 2006 Hi Steve, How are things in NY? I'm working 3 jobs here and don't get online as often. I haven't been able to get on Christian's site in ages,so I was really glad to find this group.I may see Tam this weekend & will let her know.I don't think she's online,but she could go to the library. KIT,Jeff Re: Re: Digest Number 271 Hi Jeff...U finally found us!...Tell Tammy to check this out....Steve Messenger with Voice. Make PC-to-Phone Calls to the US (and 30+ countries) for 2ยข/min or less. Quote Link to comment Share on other sites More sharing options...
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