Fw: I'm new: anyone have good results with Carnosine?

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Hi "rdklynxl" from Sue,

WOW...that's a terrrific Pangborn commentary!!!!--- and

it must reflect WHY LW sells Carnosine booster patches

WITH Glutathione booster patches.....

SINCE according to Pangborn....

"ONLY GLUTATHIONE, cysteine, and thionein can

intercept the CARNOSINE -copper transport."

I cut and pasted the paragrah that Pangborn explains

this problem...from the link you gave us...next...

Pangborn said---

"However, histidine and carnosine are powerful carriers of copper. They transport copper from the intestinal milieu into the portal blood and from there to organs and tissues in the body. And don't think you can displace copper with zinc ONCE the copper is ON HISTIDINE - you cannot. The equilibrium constant for copper II chelated to histidine is 18.3; for zinc it is 6.7 to 12.9, depending on chelate structure (Ref. Chaberek and Martell, Organic Sequestering Agents, Wiley & Sons, p.549). Because these are exponential relationships, the real difference in the constants is 10 to the 5th up to 10 to the 11th.

ONLY GLUTATHIONE, cysteine and thionein can intercept this CARNOSINE-copper transport. "

From Sue....I'm thinking... that may be another reason why so many people with spectrum disorders have low zinc levels..

---since GSH =(Glutathione )levels are low... It just emphasizes ---to me why Glutathione is a CORNERSTONE of good health.

for EVERYONE... & as it is known to be LACKING for ASD ... but CRITICAL with the use of Carnosine...

according to my Pangborn interruprtation.

(Please Let me know if your interrupretation is otherwise...)

Just today.. I was answering another question of my experience with the

dosage of LW Yage Glutathione booster patches and

LW Yage Carnosine Booster Patches...

my family have muscled tested about a 3:1 ratio

of wearing time... GSH:Carnosine..for each respectively.

This is what I said.:

From Sue

"Although everyone may be different...we have found that

for maintenance...we benefit from using the LW Yage GSH boosters

2 to 3 x per week regularly per muscle testing...

But if we are getting PRE cold symptoms... we muscle test needing them every 12 hours.

for a day or until the precold symptoms subside...then go back to every Other day use....

( It seems Like during the SUMMER when immunity is generally better for most folks... we did fine with 2 x per week.

..wearing them..in the WINTER... 3x per week.)--per muscle testing...

..But It's DIFFERENT for Carnosine.for us.

With the LW Yage Carnosine booster patches... we find them stronger..OR maybe it simply stays in the body longer than GSH...but we find ---less time is needed to attain maintenance doses...

Even from the BEGINNING of using them... we could only use them between 2-6 hours before having detox symptoms... then we would gradually increase as the detox lessened... to the 12 hours per day amt.

Now after 8 months of using them... our maintenance dose..is either

2-3 days of ONLY 6 hours of time worn or 12 hours 1-2 x times per week.

So in conclusion... we generally use the GSH patches twice-3x as often as the Carnosine patches for maintenance doses at this time .per muscle testing.

---therefore we BUY alternate orders of combo packs with just GSH packs alone ..to get that 3:1 ratio of use...or so."

Hope that helps,

Sue

Re: I'm new: anyone have good results with carnosine?

Posted by: "rdklynx1" rdklynx1@... rdklynx1

Tue Mar 11, 2008 5:29 pm (PDT)

> Thanks Sue for the additional info...I have found some research that warns of some negative effects from long term usage. If you have time, check out this link and let me know what you think. (scroll down to "Pangborn: opposing view http://www.geocities.com/fishstep/carnosine.html> 1> Hi rdklynx1 --from Sue,> Yes... we have for our ADHD / focus/etc....> and I will also send another report form a family with a 5 year old > child with ASD. next.> While Carnosine is most known for it's antiglycation.."turning old cells into new cells"> associated with anti-aging benefits... it has numerous neurological benefits as > Dr. Chez found for children with ASD in his double blind studies summarized below.> Note the benefits for SEIZURES as well.> > I find that the LW Yage Carnosine patch helps me with my memory, focus, getting things done> and motivation...not to mention it's wonderful rejuvenation of cells due to getting > rid of metabolic wastes !...> I also have a study showing Carnosine killed all 7 types of cancer found in a Petri dish. > so if anyone wants that study let me know....at st@... ...> > See BELOW for summaries on Carnosine studies..> by another product.(but keep in mind oral supplementation is not as effective as the LW patches in most cases)> More info is at the very bottom of this post regarding the NON trandermal LW Yage Carnosine patches.> > L - C A R N O S I N E> > What is Carnosine?> > The naturally-occurring amino acid is found within the human body, a by-product of > proteins digested within the body. The deep frontal part of the brain (entorhinal > cortex) is believed to be a site where carnosine tends to accumulate. It may > interact with zinc in that area, as well as having effects on GABA, a brain > neurotransmitter, which by a complex chemical reaction forms homo-carnosine.> > What Studies Have Been Done with Carnosine?> Rat and animal studies have been done with carnosine looking at "neuroprotection." > These investigations aimed to examine protective action since carnosine may be > protective of muscle and nervefunction. There have been no studies that have shown > any evidence of toxicity or teratogenicity in animals where carnosine has been > studied. Few scientifically-validated human studies have been conducted, however, > and most of the information one finds about carnosine's claims are of the quality > found on the internet. Claims have been made for generic carnosine/carnosine > formulations aiding in combating a range of maladies from Alzheimer's to body > building.> > Why Carnosine, then?> Recent MRI studies by Petroff and colleagues (2001) examining levels of brain > chemistry showed a relationship between homo-carnosine and GABA in temporal > lobe and generalized myoclonic epilepsies. These authors described homo-carnosine > levels that may correlate with SEIZURE CONTROL even when GABA response is defective > in human studies. Dr. Chez was intrigued by the results of this study, and thus began > a study in June, 2001 that aimed to test if supplementing carnosine orally could > enhance seizure protection in children who were already on anticonvulsants and who > had recurrent SEIZURES despite being on standard drug therapy. He hypothesized that > the addition of carnosine could DECREASE seizure frequency and so began an > open-label study of carnosine which he acquired via an industrial chemical company.> > The Open-Label Study> A total of 75 children, who had "failed" multiple antiepilepticmedications in an effort > to stop their seizures (including steroids and the Ketogenic diet) with histories of > partial or generalized EPILEPSY entered the open-label study. The majority had > fronto-temporal lobe seizures, or generalized epilepsy. Approximately 25% had EEGs to > directly compare before and after starting the carnosine. Many patients had > reductions in seizure frequency, but without EEG correlation. Two sisters with> hypsarrythmia/Lennox-Gastaut variant both showed dramatic improvements> in EEG amplitude, spike frequency, and background activity. In three other patients with > primary or secondary generalized spike and wave patterns or Lennox-Gastaut type > patterns, EEG amplitude and spike frequency improved with carnosine in dosages > of 800-2,000 mg. per day. Dosage was titrated upward depending upon bodyweight. > No side effects were reported.Unexpectedly, parental diaries showed a pattern of > comments related to gains in cognitive domains including language, alertness, > energy levels, and even gross motor ability. Dr. Chez was motivated by such reports > in addition to comments from other professionals that worked simultaneously with > the children (e.g., speech therapists) who, unaware that children were on the new > supplement, spontaneously stated that individual children were showing incremental > gains not previously seen. Expressive language was described as more fluent, eye > contact more frequent, and interest in the environment was more prominent. > Dr. Chez thought that this supplement could be of benefit to children with autism or > PDD and so began to give it to children with such diagnoses in an open-label trial. > Indeed, parents reported benefits in their children after as few as 2 weeks, in the > areas of socialization, expressive language, alertness level, energy level, adaptation > to change, and curiously, gross motor planning.> > The Double-Blind Study> Because of the remarkable cognitive improvements in language, speech production > and school performance as well as social alertness, Dr. Chez felt it important to > study the effect of the supplement in children with Autistic Spectrum Disorders. > Children were included in this study if they had histories of abnormal EEG, and > had previously responded to cognitive-enhancing dementia medications (as part of a > controlled study at the office) or to anti-convulsants. A double-blind placebo > controlled study with carnosine was begun. Children were randomly placed on either > active carnosine or placebo. Expressive and receptive language measures, two > autism rating scales, and parent rating analog scales were administered at the start > and completion of the study. Results of this study indicated clinically meaningful > changes in many aspects of autistic features, and also showed that the carnosine > supplement improved children's expressive and receptive language significantly. This > is the only dietary supplement to date studied in a double-blind fashion in autism.> > Who Benefits and What are the Side Effects?> The majority of children with either epilepsy or autism treated in open label studies > by Dr. Chez benefited from carnosine supplementation. Dr.Chez estimates that > approximately 10% of children who have been on the carnosine supplement have > had reports of no improvement. A very small percentage (less than 5% of children > with epilepsy or autistic spectrum disorders) have shown increased physical> hyperactivity or verbal hyperactivity, but we are unable to ascertain if these reports > are directly related to the carnosine supplement. No sleep disturbances were > reported as a result of carnosine therapy even in dosages up to 3,000 mg. a day. > No abdominal side effects, skin rashes, or any changes in anticonvulsant blood > levels, liver functions or hematological studies. No patients had any urinary changes > or bowel habit changes from the carnosine.Many children on the autistic spectrum> were reported to increase their range of food choices with an improved range of> appetite.Responses have been seen in generalized epilepsies, focal seizure > disorders, autism, PDD, and head injury to date. Because of its effect on entorhinal > cortex, improvements in Alzheimer's disease or other frontal lobe encephalopathy may > be possible. Any syndrome that involves apraxia or expressive language delay may> benefit from this. Concurrent studies are currently being run or planned in areas of> attention disorder, Tourette's syndrome, and various learning disability syndromes of > the nonverbal type.> > > PS.....from Sue.....> One type of LW Yage patches give a continuous boost of Carnosine for a full 12 -+++hour> time period since they activate the body to produce more of it's OWN carnosine.> > ( I say ONE type..since YAGE patches come in sets of either > 1. One pkg. of Carnosine booster..PLUS one pkg. of GSH boosters> OR> 2. TWO pks. of the GSH =( Glutathione boosters ) alone.)> > They are NON transdermal...and work using resonant energy (similar to radio waves)> to achieve this effect...when activated by the bodies INFRARED heat even up to 6 inches away from the body....so they will work ON CLOTHING as well as the skin.> > There are many studies done on the effectiveness of the various patches> shown on the website... www.lifewave.com/jhennings. and a short 8 minute video > called The Lifewave Report that explains the technology.> 4. > I'm new: anyone have good results with carnosine? > Posted by: "rdklynx1" rdklynx1@... rdklynx1 > Mon Mar 10, 2008 5:25 pm (PDT) > I am considering adding carnosine to my 4 1/2 yr. son's biomeds. Has > anyone had good results with this? I've researched that this is a small > natural protein that has had great results acting as a > neurotransmitter. A double blind study done at Autism and Epilepsy > Specialty Services in Lake Bluff, Il. resulted in an increase in verbal > abilities with 30 out of 31 children with autism.> > Check out the website for more details:> > http://autismcoach.com/Carnosine%20Study.htm> > > Back to top > Reply to sender | Reply to group | Reply via web post > Messages in this topic (1)>

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